Vermot Lab

Vermot Lab

@vermotlab.bsky.social

We study mechanotransduction during heart valve morphogenesis, blood vessel formation and left-right asymmetry in zebrafish at #ImperialCollegeLondon vermotlab.com x.com/VermotLab

929 Followers 452 Following 10 Posts Joined Dec 2024
2 months ago
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Check out our latest preprint on the cellular mechanical basis of Voronoi tessellations in epithelia! This biophysics study is inspired by disordered tessellations observed in zebrafish hearts 🤓🐟💙 #SulaimaanLim #ChiuFanLeeLab

arxiv.org/html/2512.13...

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5 months ago
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🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.

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5 months ago
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🔬For 22 years, we have been organizing #Mifobio "Functional Microscopy for Biology" the @cnrs.fr thematic school.

🎓 Courses, Seminars, Round Tables, Workshops. The overall theme concerns #biological_imaging in its most interdisciplinary aspects.

👉 Program: imabio-cnrs.fr

#GDRImaBio #Mifobio2025

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5 months ago

Out @natcomms.nature.com:
our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀

Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!).

Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social
rdcu.be/eIJm5

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5 months ago
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Back from the London Zebrafish Research Network — a truly inspiring afternoon. Many thanks to @cvagenapantoula.bsky.social, @kkalyviotis.bsky.social and Eleni for putting together such an interactive programme, full of excellent talks - Tim 👏 - and great discussions. Zebbie research at its best!

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5 months ago
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Plasticity of ventricle position after heart looping in heterotaxy with right isomerism The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.

New publication | Science Advances www.science.org/doi/10.1126/...

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5 months ago

Development does not happen in isolation! Material properties, geometry, stiffness, fluid flows...can all steer how development unfolds. If you’re exploring these kinds of questions, we’d love to see your work @dev-journal.bsky.social
More info below ⬇️

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5 months ago
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Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

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5 months ago

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM

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5 months ago
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How do cells navigate up gradients of adhesive proteins?
🤔

Termed "Haptotaxis", this effect is ubiquitous in cell migration, but it's mechanism was poorly understood

We show that passive friction directs cells & explains complex trajectories on gradients

👉 www.nature.com/articles/s41...

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5 months ago

Deadline to register for Get Into Grad School Webinar approaching! Share with interested #undergraduates and #postbacs Registration Deadline: Thursday, September 18. bit.ly/3HFJ9BG

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6 months ago
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Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

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5 months ago
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🚨 Two weeks left to apply for the EMBL-EBI–Sanger Postdoctoral (ESPOD) Programme.

Apply by: 30 September 2025.

Ready to take the next step in your science career?
www.ebi.ac.uk/research/pos...

@sangerinstitute.bsky.social
#postdoc #sciencecareers

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6 months ago
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.@ahxanjaved.bsky.social, @sarawickstrom.bsky.social & team discover that Piezo1 balances membrane & cortex tension to stabilize intercellular junctions & maintain the epithelial barrier.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#OpenAccess

23 8 2 0
6 months ago
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New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...

88 28 3 2
6 months ago
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We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

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6 months ago
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The complex microscopic dynamics of cells in high-density epithelial tissues Epithelial tissues line the surfaces of vital organs and are often densely packed in a disordered, mechanically arrested state, referred to as jammed or glassy state. While collective migration at low...

Very happy to share our new study from CAM team @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social (MPZPM) on the unanticipated “hidden fluidity” in jammed epithelia. Congrats to Yuan Shen and great collaboration with Walter Kob.
www.biorxiv.org/content/10.1...

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6 months ago

OK--fluorescent protein friends. We want an antibody to TagRFP that works in immunofluorescence. Any suggestions? Re-post please

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6 months ago
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Purine Molecular Interactions Determine Anisotropic Shape of Zebrafish Biogenic Crystals Many organisms self-organize crystals for vision, pigmentation, or storage. In zebrafish, iridophores produce anisotropic crystals in iridosomes. Using imaging and genetic tools, crystal growth is sh...

The first paper of our lab is finally out, and I feel very proud and grateful to our wonderful team! @Jannik Rothkegel, @Sylvia Kaufmann, @Michaela Wilsch-Braueninger, @Catarina Lopes <3
onlinelibrary.wiley.com/doi/10.1002/...

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6 months ago
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🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...

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6 months ago

Happy to see our work, led by @ivanbassi.bsky.social, out today in @jem.org! #Zebrafish help us find new treatments for a #rare_disease affecting #lymphatic vessels! Congrats to all authors and thanks to #MDBRide4Rare, #ODC_UPenn, @erc.europa.eu for support @weizmanninstitute.bsky.social

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8 months ago
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Call for 20 Assistant Professor positions Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...

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6 months ago
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Molecular and Developmental Biology of Drosophila The principal theme of the EMBO Workshop is the Molecular and Developmental Biology of Drosophila. Supported by EMBO over four decades, this will be the 24th biennial “Crete meeting”. With the a…

Join junior group leaders using #Drosophila to understand development, #CellBiology, #evolution and more at the EMBO Workshop on Molecular and Developmental Biology of Drosophila, 21–27 June 2026 in Kolymbari, Greece.

Deadline: 3 November

meetings.embo.org/event/26-dro...
#EMBOevents #GeneSky 🧪

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6 months ago

🇬🇧 We are #hiring a Financial Assistant to join our admin team at Physics of Life! Do you thrive in an international environment and speak both English and German? We would love to hear from you!

Apply and learn more here: tud.link/rywtux
🗓️Application deadline: 21st August

#financejobs #dresden

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6 months ago
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🚨 We’re hiring. The Roman group study how cells communicate to keep organs healthy – and how this goes wrong in disease & ageing. Level A (Postdoc) | Clayton campus Apply by 8 Sept: careers.pageuppeople.com/513/cw/en/jo...

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11 months ago
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Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenesis - the Node Behind the Paper Story of “Combined forces of hydrostatic pressure and actin polymerisation drive endothelial tip cell migration and sprouting angiogenesis”.

Thank you @the-node.bsky.social‬ for inviting me to write a 'Behind the Story' piece on our recent study!

Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenesis thenode.biologists.com/exploring-th...

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7 months ago
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Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model Nature Communications - Here the authors show that Plasmodium falciparum egress products disrupt endothelial barrier and activate JAK-STAT and interferon type response in a 3D blood-brain barrier...

We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum.

First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social

rdcu.be/ezBl7

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7 months ago
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Very happy to see our preprint on how the mechanosensitive ion channel Piezo1 controls intercellular junction maturation by balancing cortex and membrane tension now published in @jcellsci.bsky.social Congratulations to Ahsan & team! journals.biologists.com/jcs/article/...

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7 months ago

Out now! Our very first paper@crick.ac.uk, an impressive feat by @tobyandrews.bsky.social where we show how a developing heart grows and scales up its morphological complexity to keep beating...an excellent summary below ⬇️
www.cell.com/developmenta...

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7 months ago
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Pulsatile flow dynamics determine pulmonary arterial architecture BACKGROUND Single ventricle congenital heart disease (SV-CHD) is a uniformly lethal condition. Survival depends upon the Glenn surgery, which shunts venous blood directly to the pulmonary arteries wit...

Happy to share our work on the role of biomechanical PULSATILITY on lung vessels.

Following surgery to alleviate overload in kids with single ventricle hearts, lung arteries form AVMs. #DevBio #EndothelialCell #CHD

Beautiful work from Steve Spurgin. #DevBio 🫁 🫀 ❤️‍🩹

www.biorxiv.org/content/10.1...

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