Anthony Ramnauth

RNA localization to nuclear speckles follows splicing logic Abstract. Nuclear speckles are membraneless organelles implicated in multiple RNA processing steps. In this work, we systematically characterize the sequen

Awesome new work from Jingyi Fei's lab in collaboration with Oded Regev's group.

RNA localization to nuclear speckles follows splicing logic url: academic.oup.com/nar/article/...

Too excited about this image to wait for #FluorescenceFriday 🔬🤩👩‍🔬. Serotonin neurons 🟣 in the raphe nucleus along the midline of the human brainstem 🧠, flanked bilaterally by norepinephrine neurons 🔴 in locus coeruleus. Image credit to @ishbeldelrosario.bsky.social @svitlanabach.bsky.social

U.S. at Fault in Strike on School in Iran, Preliminary Inquiry Says Outdated targeting data may have resulted in a mistaken missile strike, according to the ongoing military investigation, which undercuts President Trump’s assertion that Iran could be to blame.

Breaking News: The U.S. was responsible for a missile strike on an Iranian elementary school, an ongoing military investigation found. The inquiry said the strike — which Iranian officials said killed at least 175 people, most of them children — was the result of a targeting mistake.

Deconstruction of a memory engram reveals distinct ensembles recruited at learning - Nature Neuroscience Pouget et al. identified distinct CA1 neuron ensembles active during specific moments of fear learning and uncovered the core engram essential for memory formation.

Deconstruction of a #memory #engram reveals distinct #ensembles recruited at #learning
doi.org/10.1038/s415...

Competitive interactions shape mammalian brain network dynamics and computation - Nature Neuroscience Brain network architecture may balance cooperation and competition across circuits. Here the authors use computational whole-brain modeling across three species to show that models with competition ar...

Competitive interactions shape #mammalian #brain network dynamics and #computation
doi.org/10.1038/s415...

Functional recovery of the adult murine hippocampus after cryopreservation by vitrification | PNAS Cryopreserving the adult brain is challenging due to damage from ice formation, and traditional freezing methods fail to maintain neural architectu...

Functional recovery of the adult murine #hippocampus after #cryopreservation by #vitrification
www.pnas.org/doi/10.1073/...

Comprehensive transcriptomic and proteomic profiling of mTOR-related epilepsy https://www.biorxiv.org/content/10.64898/2026.03.10.710809v1

Why isn’t Elizabeth Warren the Senate Minority Leader?

BREAKING: As ‌many as 150 US troops have ​been wounded ​so far in ⁠the war with ​Iran.

Far higher than Pentagon which claims that only 8 have been wounded.

This is a REUTERS story, not Iranian propaganda. They have it from two sources.

Meet the ultimate gatekeeper of the nucleus. This molecular machine determines what compounds are welcome inside and which shall not pass. The mechanism behind its selectivity remains a mystery. www.quantamagazine.org/disorder-dri...

Gene regulatory networks: from correlative models to causal explanations - Nature Reviews Genetics In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without compromising explanatory power.

"GRNs, which should provide mechanistic explanations, are increasingly reduced to statistical correlations — ‘hairballs’ that fail to capture molecular causation"

By Maizels and @jamesbriscoe.bsky.social

www.nature.com/articles/s41...

Video appears to show U.S. cruise missile striking Iranian school compound The seven-second video was released by Iranian state media and directly contradicts statements made by President Trump, who said Iran was responsible for the strike.

The Iranian girls’ school was hit by a US tomahawk cruise missile. NPR has confirmed the footage.

They corrected it. That was quick!

Astrocytic H3 receptors regulate anxiety through GABA signaling Li et al. identify a hypothalamic histaminergic circuit projecting to hippocampal vCA1 that encodes anxiogenic contexts. This pathway engages astrocytic H3 receptors, triggering Ca2+ signals and subse...

#Astrocytic H3 receptors regulate #anxiety through #GABA signaling: Neuron www.cell.com/neuron/fullt...

Light-directed evolution of dynamic, multi-state, and computational protein functionalities Optovolution leverages optogenetics and the yeast cell cycle to impose rapid, tunable selection, enabling the continuous evolution of light-responsive regulators, logic gates, and other complex protei...

I like the name they came up with: "Optovolution"

Light-directed evolution of dynamic, multi-state, and computational protein functionalities: Cell www.cell.com/cell/fulltex...

Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy Alzheimer’s disease (AD) is the leading cause of dementia and is characterized by progressive amyloid accumulation followed by tau-mediated neurodegeneration. Despite advances in anti-amyloid immunoth...

Targeting #amyloid-β pathology by chimeric antigen receptor #astrocyte (CAR-A) therapy | Science www.science.org/doi/10.1126/...

Transcriptional regulation of ventral hippocampus-nucleus accumbens circuit excitability drives cocaine seeking ΔFosB induces calreticulin to decrease excitability of ventral hippocampus-accumbens projections and drive cocaine seeking.

#Transcriptional regulation of ventral #hippocampus- #nucleusaccumbens circuit excitability drives #cocaine seeking | Science Advances www.science.org/doi/10.1126/...

𝗪𝗵𝗮𝘁'𝘀 𝘁𝗵𝗲 𝗿𝗲𝗹𝗮𝘁𝗶𝗼𝗻𝘀𝗵𝗶𝗽 𝗯𝗲𝘁𝘄𝗲𝗲𝗻 𝗺𝗮𝗻𝗶𝗳𝗼𝗹𝗱𝘀 𝗮𝗻𝗱 𝗿𝗲𝗰𝘂𝗿𝗿𝗲𝗻𝘁 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻?
This looks like a must read (suppl material bursting with goodies).
#neuroskeyence
doi.org/10.1016/j.ne...

Six federal scientists run out by Trump talk about the work left undone | CNN Federal data shows the NIH lost about 4,400 people — more than 20% of its workforce. Scientists say the departures harm the U.S.’ ability to respond to disease outbreaks, develop treatments for chroni...

The number of people employed at the NIH is at its lowest level in at least two decades.

Hear from six scientists run out by Trump and the work they left behind on cancer research, tick-borne diseases, and more.

Me + @k-hought.bsky.social @kffhealthnews.org for @cnn.com www.cnn.com/2026/03/05/h...

Nature Report, Killed by Trump, Is Released Independently

Scientists and other experts were preparing an assessment of the health of nature in the US when Trump returned to the White House. He canceled the report. The researchers went ahead and compiled it on their own. This week, they released a 868-p draft for public comment and scientific review.

So, it looks like The Journal of Neuroscience has misspelt my surname... it's Anthony D. Ramnauth...
www.jneurosci.org/content/earl...

AI Translations Are Adding ‘Hallucinations’ to Wikipedia Articles AI translated articles swapped sources or added unsourced sentences with no explanation, while others added paragraphs sourced from completely unrelated material.

Wikipedia editors investigated how OKA was operating and found that it was mostly relying on cheap labor from contractors in the Global South, and that these contractors were instructed to copy/paste articles to popular LLMs to produce translations.

Trump Administration Live Updates: President Ousts Noem as Homeland Security Secretary

Trump Administration Live Updates: President Ousts Noem as Homeland Security Secretary www.nytimes.com/live/2026/03...

CPT Josephine Guilbeau
Marine Corps veteran arrested inside the Senate Armed service committee hearing and then attacked by Senator Sheehy protesting war for Israel.
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WASHINGTON (AP) — White House says Spain has agreed to cooperate with US operations in Mideast after Trump threatened financial penalties.

MADRID (AP) — Spain's government denies cooperation with US operations in the Middle East, contradicting White House.

With this war on Iran costing $1B per day, we are now at 4$B, an amount that would fund 3,200 five year NIH biomedical research grants.

Florence ICE detainee dead after untreated tooth infection, official says An ICE detainee, who had been at a Florence detention center for four months, died Monday following an untreated tooth infection.

An ICE detainee in Arizona has died of a TOOTH INFECTION after it went untreated for weeks, a local official says. He was a Haitian asylum seeker imprisoned in Florence, Arizona. @emilybregel.bsky.social reports.
tucson.com/news/local/b...

a large screen shows a man 's face and says ingsoc ALT: a large screen shows a man 's face and says ingsoc

So... A friend was supposed to give a PURELY SCIENTIFIC talk at NIH within the next couple of weeks and it was cancelled because of a "new process" where all speakers/talks have to be CLEARED BY A POLITICAL APPOINTEE.

A photo distributed by Iranian state media showed thousands in the streets of a town in southern Iran on Tuesday during the funeral for victims of an airstrike on a girls’ elementary school that killed at least 175 people, many of them students, on Saturday. nyti.ms/3N6jh4i

idk that seems to be the understatement of the week. this is actually happening, postdocs and RAs are being let go, and projects falter. 'could face funding gaps'? this is actually happening at a large scale. 'Worry' doesnt reflect the existential crisis that many of my colleagues are in.