Anthony Ramnauth

Some of these structures are breathtaking!

Nobel Prize in Chemistry 2025 The Nobel Prize in Chemistry 2025 was awarded jointly to Susumu Kitagawa, Richard Robson and Omar M. Yaghi "for the development of metal–organic frameworks"

"...Yaghi’s research group has harvested water from the desert air of Arizona. During the night, their #MOF #material captured water vapour from the air. When dawn came and the sun heated the material, they were able to collect the water."
www.nobelprize.org/prizes/chemi...

‘Google for DNA’ brings order to biology’s big data MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.

Metagraph: the new search engine that can quickly sift through the staggering volumes of biological data housed in public repositories

go.nature.com/48lM8Kh

Ultra-sensitive DNA sequencing maps mutations that precede cancer Scientists have used low-error genome-sequencing methods in normal tissues from large cohorts of individuals to scan for mutations that set the stage for cancer.

Scientists have used low-error genome-sequencing methods in normal tissues from large cohorts of individuals to scan for mutations that set the stage for cancer

go.nature.com/42vakWS

"A Palestinian, son of Palestinians displaced from Gaza (Al-Masmiyya) to Jordan, wins the Nobel Prize in Chemistry... Professor Omar Munis Yaghi from the University of Berkeley!!

..Some members of the Yaghi family are still under the rubble in Gaza!"

- Jacob Hanna

Winning a Nobel Prize Interrupted His Off-the-Grid Vacation Fred Ramsdell found out about his Nobel Prize nearly 12 hours after it was announced because he was on vacation in the Rockies.

Fred Ramsdell was parked at a campground in Montana on Monday when his wife suddenly started shouting. He first thought that maybe she had seen a grizzly bear. Instead, she had regained cell service and had seen a flood of text messages with the same news. “You just won the Nobel Prize!” she yelled.

Neural coding of choice and outcome are modulated by uncertainty in orbitofrontal but not secondary motor cortex - Nature Communications Neural mechanisms underlying flexible learning and decision-making are not fully understood. Using single-cell calcium imaging, authors here found that neurons in orbitofrontal and secondary motor cortex exhibit complementary roles in reward learning, with neurons in the former exerting a sustained role in conditions of uncertainty.

🎇 Excited to finally share JL Romero Sosa’s publication! Results are from single-cell imaging in different subregions of rat frontal cortex during ✨de novo learning. Spoiler: everything is not everywhere all at once www.nature.com/articles/s41...

The official website of the Nobel Prize - NobelPrize.org The Nobel Prize rewards science, humanism and peace efforts. This is one of the central concepts in the will of Alfred Nobel, and it also permeates the outreach activities that have been developed for...

Six of the nine Nobel Prize winners this year work in the U.S.
Three of the six were born outside the U.S., which is the pattern most years. No country has benefited more from welcoming immigrants from around the world.
www.nobelprize.org

What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social

rupress.org/jcb/article-...

What Americans Die from?

And what the media reports on...

Our World in Data ourworldindata.org/does-the-new...

And look at this graphic abstract….. 😱🤯

How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions The brain constantly generates predictions based on one’s knowledge of the world, as captured in memory. When these predictions are in error, our knowledge base must be revised to remain relevant. Her...

How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions: Trends in Neurosciences www.cell.com/trends/neuro...

Johns Hopkins sophomore student Florin Selaru develops a new scheme to deconvolve colors in histological sections for digital pathology.

It greatly outperforms traditional linear color deconvolution.

Congrats Florin!

Read his paper here: www.biorxiv.org/content/10.1...

a man in a blue sweater is standing in a dark room with his hands up . ALT: a man in a blue sweater is standing in a dark room with his hands up .

#agenticcoding can leave you feeling like Tony Stark. But just like #math class, you gotta check your work.

Neurons can communicate via hidden network of nanotubes, study finds Tubes in mouse and human brains may also influence spread of brain disease

Neurons can communicate via hidden network of nanotubes, study finds | Science | AAAS www.science.org/content/arti...

Goodall transcribes field notes by lamplight in Tanzania’s Gombe Stream National Park c.1960

Arousal as a universal embedding for spatiotemporal brain dynamics - Nature Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.

Nature research paper: Arousal as a universal embedding for spatiotemporal brain dynamics

go.nature.com/4nMUgYz

I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !

With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics

Your reminder that many of the muscles, nerves and bones you use to hear and talk with correspond to gill structures in fish. 🧪 #evolution #paleontology

Worried about microplastics around you. We are excited about utilization of our low cost Raman microscopy tools in identifying microplastic pollution - from human body to California beaches to deep ocean.

Read the story here:
news.stanford.edu/stories/2025...

www.pnas.org/doi/10.1073/...

Prehistoric camel art pointed to precious water sources in the Arabian Desert Hunter-gatherers may have used the engravings to find water 12,000 years ago

Hunter-gatherers may have used engravings to find water in the parched deserts of the Arabian Peninsula 12,000 years ago. https://scim.ag/4nql413

Forebrain assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects Walsh et al. establish a human forebrain assembloid protocol that supports the derivation of bona fide PVALB+ cortical interneurons and employ it to model schizophrenia in disease-associated structura...

Forebrain assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects www.cell.com/neuron/fullt...

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

Polygenic and developmental profiles of autism differ by age at diagnosis - Nature A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.

"Earlier- & later-diagnosed autism have different developmental trajectories & genetic profiles. The findings have important implications for how we conceptualize autism & provide a model to explain some of its diversity." @vw1234.bsky.social & an international team report today in @nature.com: 👇🧪

NIH awarded 37 percent fewer neuroscience-related grants in 2025 than in past years But the agency has spent nearly its entire budget for this fiscal year, which ends tomorrow.

www.thetransmitter.org/funding/nih-...

Alien: Earth reminds me of the sci-fi horror I loved as a kid. Ya I know, a kid shouldn't be watching such bloody stuff, but it did help foster my love for science.

Role of molecularly defined lateral septum cell types and circuits in social behaviors - Neuropsychopharmacology Neuropsychopharmacology - Role of molecularly defined lateral septum cell types and circuits in social behaviors

New Hot Topics piece from @rphillips3.bsky.social and Stephanie Page in @npp-journal.bsky.social describing emerging insights on roles of molecularly-defined cell types in the lateral septum, which serves as a hub for coordinating diverse social behaviors.

www.nature.com/articles/s41...

My dumbass decided to take the bus home while there is a UN general assembly. Been stuck in traffic for over an hour and still stuck.

Some proteins are primarily regulated by one mechanism: RNA abundance, translation, or clearance.

The regulation of most proteins is dominated by different regulatory mechanisms across cell types.

Gratifyingly, this complex regulation defines simple rules ⬇️

www.biorxiv.org/content/10.1...

Evidence for an active handoff between hemispheres during target tracking The brain has somewhat separate cognitive resources for the left and right sides of our visual field. Despite this lateralization, we have a smooth and unified perception of our environment. This rais...

New paper!
Evidence for an active handoff between hemispheres during target tracking
www.jneurosci.org/content/earl...
#neuroscience