Timothy O'Leary

Timothy O'Leary

@timothyoleary.bsky.social

Professor of Information Engineering and Neuroscience, University of Cambridge

2,333 Followers 392 Following 317 Posts Joined Oct 2023
4 hours ago

I made an exhaustive list of biologically implausible algorithms as a handy reference for reviewing and triaging papers:

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4 hours ago

Huge, huge bummer. This is one of the most promising technologies I've ever covered.

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1 day ago

Ooh ohh but but but BUT... I think you'll find that correlation does NOT imply causation.

That's more of a comment than a question.

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1 day ago

seeing as I'm not actually attending Cosyne, and that by next year the AIs will have taken over, I feel quite safe sitting in an undisclosed location, shitposting about the future of comp neuro...

so not that different from actually attending, apart from the absence of delicious Portuguese cuisine

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1 day ago

oooh... that is controversial!

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1 day ago

Modish? I never saw any mopeds or flick knife fights at cosyne, but I've only been a few times.

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1 day ago

well, minimally I think we can agree that Cosyne doesn't know where it is going!

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1 day ago

Does anyone out there still do physiology? I have a plea. All experiments have limitations that any competent physiologist knows about but can't spend 28 pages detailing.

So if you ding a paper or grant on textbook issues that the authors likely considered, don't complain that you're a dying breed.

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1 day ago

Yes, but it does sample it

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1 day ago

A single plot shows computational neuroscience doesn't really know where it is heading:

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2 days ago

finally!

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2 days ago

Yeah, but there's a problem: AI is THE technology that lets small states level the playing field, especially now that they feel targeted. No matter how many pacts big nations pretend to make, open source/distilled AIs (no matter how crappy) are far cheaper and easier to conceal than WMD programs.

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3 days ago

If it's in English you just converge to the letter e

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4 days ago
Preview
How Congress can restore the independence of US science Members must go beyond reinstating US government research spending and re-establish decentralized governance at the National Institutes of Health and other agencies.

The most impt change at #NIH and to US science this year is bigger than grant cancellations— it’s how the agency is governed.

For 75 years NIH has been largely independent of presidential control. That’s changed this year. New piece from me and @nataliebaviles.bsky.social in @nature.com
🧪

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6 days ago
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Low-D you say...

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1 week ago
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6 days ago
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Uta Frith: why I no longer think autism is a spectrum The autism spectrum has widened to the point of collapse, affecting how teachers should support autistic pupils in the classroom, researcher Uta Frith tells Helen Amass

Wise words from an expert on autism
www.tes.com/magazine/tea...

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1 week ago
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2 weeks ago
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Two-photon calcium imaging at 24,000 lines/s, with the resonant axis spanning 4x what other systems can do. Inertia-free. Diffraction-limited. No tradeoffs. Che-Hang Yu developed a 4x angle multiplier for laser scanning. His paper is out today: opg.optica.org/optica/fullt... 1/n #fluorescenceFriday

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2 weeks ago

Embedding unreliable AI deep into the source code of the military without human oversight is the single stupidest thing we could do as a species.

And that is *exactly* what the United States is about to do.

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2 weeks ago

Yes! Some clear thinking. Once we move away from "species x is a good/bad model for y because of z handpicked reasons" we can do science.

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2 weeks ago

In 2023 a bill to prevent AI from autonomously launching nuclear weapons *failed to pass*. This was apparently not newsworthy.

www.congress.gov/bill/118th-c...

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2 weeks ago
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America, and probably the world, stands on a precipice. Call you Congresspeople, right now.

The urgent plea of @garymarcus.bsky.social demands rapid action: the US Military, in the hands of fascists, seeks to bend Anthropic to the knee in the aims of incorporating AI into military weaponry. Gary asks us to call our political representatives right now. I just did. Now it's your turn.

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2 weeks ago

A summary of the last decade's news:

2016: the cunts are in charge now
2026: documents reveal that the cunts were always in charge

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2 weeks ago

Calcium spikes know which way the wind blows!

Lily Nguyen and I wrote a dispatch on this fascinating work led by Itzel Ishida+@sethisachin.bsky.social+Gaby Maimon!

authors.elsevier.com/a/1mfk53QW8S...

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2 weeks ago
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LLMs should be a private cognitive tool, like a calculator, which is not currently possible under our existing model of corporate AI. Crucially, they do not think and have no agency, again in the same way as a calculator

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2 weeks ago

for those who are paywalled or want to read the original research instead of the headline: arxiv.org/pdf/2602.14740

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2 weeks ago

Broader engineering principles than those most of us are familiar with, for sure!

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2 weeks ago
Macro photo of a brown stink bug in face view on a leaf, guarding a tightly-clustered bunch of eggs that are shaped and colored exactly like a full tray of dark beer with foam on top.

Finally, the bug is back with a round of the Guinness.

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2 weeks ago
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Reverse Engineering of Biological Complexity Advanced technologies and biology have extremely different physical implementations, but they are far more alike in systems-level organization than is widely appreciated. Convergent evolution in both ...

No! It's the other way around. Engineering principles *generate* complex systems:

www.science.org/doi/10.1126/...

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