EuroIntervention

"Predictors of long-term structural valve deterioration and failure after transcatheter aortic valve implantation" by T. Palmerini et al. #cardiosky #cardiomed #cardiotwitter

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This meta-analysis of randomised trials showed that TEER plus guideline-directed medical therapy reduces heart failure hospitalisations in patients with symptomatic functional mitral regurgitation, compared with medical therapy alone. #cardiosky

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After PFO closure, continuous implantable cardiac monitoring revealed a high incidence of atrial fibrillation.
Most episodes are asymptomatic and paroxysmal, with a significant proportion occurring beyond 30 days. #cardiosky

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Rare complication after TAVI: embolisation and delayed twisting of a balloon-expandable valve led to spinal hypoperfusion and paraplegia in a 78y-old patient. Prompt valve-in-valve implantation restored flow with full neurological recovery. #cardiosky
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New State-of-the-Art in EuroIntervention: lesion stratification with intracoronary imaging, covering morphology-guided PCI, high-risk plaque assessment, and the emerging role of AI in integrated morphofunctional evaluation. #cardiosky
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REPEAT-QFR - FAVOR III Europe substudy

In-procedure QFR demonstrated moderate diagnostic accuracy and reproducibility, with performance influenced by angiographic and analysis quality. #cardiosky

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High-risk plaques are identifiable, but their clinical event rate remains low
Evidence from PROSPECT and PREVENT suggests that, under OMT, prophylactic PCI mainly prevents future revascularisationsupporting a cautious, wait-and-see approach.
#Cardiosky
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In STEMI with 3-vessel OCT imaging, long-term risk appears driven more by non-ruptured TCFA than by plaque rupture itself.
These data refine the concept of pancoronary vulnerability and may inform future risk stratification. #cardiosky

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New AOP in EuroIntervention
Successful retrieval of a stuck TAVI device via the LV apex after balloon alignment failure, followed by transapical implantation.

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#cardiosky

This expert review outlines when and how to perform endomyocardial biopsy in current practice, with a new Central Illustration offering a clear visual synthesis of patient selection, technique, and downstream clinical implications.
#cardiosky
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🔥New issue out today!
Expert review on endomyocardial biopsy, high-risk plaque interventions, non-culprit plaque rupture, non-invasive CMD assessment, QFR reproducibility, STEMI in large coronary arteries — and more.
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#cardiosky #cardioEd #cardiotwitter

In this large real-world cohort, annular calcium volume was independently associated with ACURATE neo/neo2 valve underexpansion, while post-dilatation reduced deformation risk.
#cardiosky
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📢 New in EuroIntervention: a comprehensive State-of-the-Art on transcatheter edge-to-edge repair (TEER) for secondary mitral regurgitation.
From evolving SMR phenotypes to trial data, device innovation, patient selection & 2025 guideline updates.
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In SORT OUT X, the dual-therapy CD34 antibody-covered COMBO stent showed higher target lesion failure vs the Orsiro sirolimus-eluting stent at 5 years, driven by early revascularisation, with similar outcomes beyond year 1.
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#cardiosky

🔥NEW JAA
Redo surgery or transcatheter valve-in-valve?
The SURVIV trial is the first randomized study comparing mitral valve-in-valve with redo surgical replacement for failed bioprosthetic valves, aiming to guide evidence-based care
#cardiosky
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Exercise-based invasive physiology reveals distinct CMD phenotypes in ANOCA, including impaired exercise-induced vasodilation despite normal pharmacological hyperaemia.
#ANOCA #CMD #CoronaryPhysiology #cardiosky
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🔥 NEW IN EIJ
Watchman FLX showed improved safety and performance compared with Watchman 2.5 in a large matched analysis. #LAAC #CardioTwitter
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🔥 New issue out today!

Featuring:
• TEER in MR
• Watchman FLX vs 2.5
• ACURATE neo underexpansion
• Valve-in-root TAVI
• CMD endotypes
• SORT OUT X (5y)
• RADIANCE-HTN TRIO antihypertensives.

Don’t miss it!

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#cardiosky #cardiology #cathlab

A 69-year-old high-risk patient treated with the FDA-approved EVOQUE TTVR showed trivial TR, stable gradients, and major clinical improvement at 5 years with no structural degeneration. Early evidence of impressive durability. #TTVR #cardiosky
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New pre-specified MASTER DAPT analysis:
In high-bleeding-risk PCI patients, CKD did not alter the benefits of a 1-month abbreviated antiplatelet regimen. NACE and MACCE were similar to standard therapy, while bleeding was consistently lower
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#cardiosky

In a 79-year-old with refractory angina, double Reducer implantation was required after device migration, with CT later revealing non-occlusive sinus thrombosis. After anticoagulation, the sinus remained patent and symptoms improved to CCS I. #cardiosky
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Early results from the TRICURE FIH study show that the Topaz TTVR system achieved complete TR elimination, with all patients reaching none/mild TR at 30 days and 100% device success. A step forward for TTVR in high-risk TR patients.
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#cardiosky

NEW State-of-the-Art review on #calcifiednodules in PCI, detailing their morphology, imaging-based identification with OCT/IVUS, deformation patterns, and implications for optimal lesion preparation and stent expansion. #cardiosky
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NEW STATE OF THE ART
From ECG patterns and high-sensitivity troponins to risk scores and timing of invasive strategies, this comprehensive overview highlights what truly guides decision-making in 2025. #cardiosky
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December Issue now online: SOTA on NSTE-ACS and calcified nodules, plus new data on β-blockers post-MI, antiplatelet therapy in CKD-HBR, and thrombosis after Reducer migration. #cardiosky
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NEW EXPERT CONSENSUS
This scientific statement provided a comprehensive framework for managing patients with transvalvular CIED leads undergoing transcatheter tricuspid interventions. Read more here: t.co/BwfONSXT02 #cardiosky

Long-term outcomes after BE-TAVI appear independent of annular size. In 2,699 patients, mortality and BVF at 7 years were similar between small and large annuli.
#TAVI #StructuralHeart #cardiosky
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New data from the OCEAN-TAVI CT substudy highlight the role of THV deformation and asymmetric leaflet expansion as key predictors, with greater HALT burden linked to higher gradients. #cardiosky #THV #stucturalcardiology
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This viewpoint reflects on the ACURATE platform withdrawal, noting trial limitations, procedural factors, and promising registry data.
#TAVI #Cardiosky #PCRLV
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Early results of the DurAVR THV in small aortic annuli show excellent 30-day performance: low gradients, large EOAs, minimal PPM and no mortality.
SIMULTANEOUS PUBLICATION #PCRLV @CARDIOSKY
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