Abhimanyu

Abhimanyu

@drabhi.bsky.social

Studying Host-pathogen interaction , Epigenetics , single cell omics, tuberculosis, DNA methylation , metabolism. Staff Scientist #Uchicago; life enthusiast, an aspiring polymath; creative, Indian. Let there be light in the world .

35 Followers 77 Following 9 Posts Joined Nov 2024
2 months ago
Preview
Seasonal and Vitamin D3 mediated methylome reprogramming of peripheral immune cells and anti-viral responses Seasonality of inflammatory and infectious diseases is associated with several factors, including serum vitamin D fluctuations and immunological state. We longitudinally investigated peripheral blood ...

Thrilled to share this preprint. Years in making but so glad this is out ! www.medrxiv.org/content/10.6...

1 0 0 0
5 months ago
Post image

This case series highlights risk factors for infection by a non-tuberculous mycobacterium.

Ananya Gupta @drabhi.bsky.social et al. link GATA2 mutation in the context of immune dysfunction to enhanced susceptibility to M. heamophilum infection in humans: buff.ly/pPIhSlx

2 3 2 1
7 months ago
JCI Insight - GATA2 mutation is associated with immune dysfunction and increased Mycobacterium haemophilum susceptibility in immunocompromised individuals

Happy to share this interesting study which is now in press. We found specific Non-tuberculous mycobacterial susceptibility linked to GATA2 mutation in immunocompromised individuals @uchicagobsd.bsky.social @jci-insight.bsky.social insight.jci.org/articles/vie...

0 1 0 0
7 months ago
Preview
Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery MS-based immunopeptidomics can facilitate vaccine antigen discovery, but self-MHC peptides greatly outnumber pathogen-derived MHC peptides, presenting a ch

Newest paper from the lab out today (doi.org/10.1084/jem....)! Here, we describe PathMHC, a novel MS-based approach to identify rare pathogen-derived peptides on MHC-I and MHC-II. We apply this to a range of pathogens Mtb, SARS-CoV-2, and Listeria.

30 8 1 0
8 months ago

Congratulations Bryan !

1 0 0 0
10 months ago
Post image

In the midst of everything take a break , protect your sanity and refuel to keep at it . #easter #timeoff #vitaminsea

0 0 0 0
1 year ago
Post image

Happy to be part of this cool paper ! BCG trial for prevention of COVID-19 in healthcare workers, interrupted with speedy arrival of the COVID vaccines. The vaccinated cohort 12-months later show improved COVID-19 immunity, key player DNA methylation! #BCG #DNAmethylation @globaltb.bsky.social

0 1 0 0
1 year ago
Golden Gate Bridge at Sunrise At the view point in Yosemite El Captain

Happy 2025! Ready to get back to the science after a reset trip to beautiful #sanfrancisco #yosemite

1 0 0 0
1 year ago

Congrats Bianca and team !

0 0 0 0
1 year ago

A good day spent in listening to talks from four neighboring labs which are incidentally on the same floor . From #proteinengineering , #phageengineering , hightroughput #microfluidics and traditional conditional knockout #micemodels . #uchicago . Science is in good hands !

1 0 0 0
1 year ago
Preview
TB reclaims title of deadliest infectious disease. That's an 'outrage' says WHO DIslodged by COVID early in the pandemic, tuberculosis is once again the infectious disease that takes the most lives each year. And the number of cases set a new record. What's going on?

“Money reigns as perhaps the biggest obstacle” 🧪🩺

16 6 0 0
1 year ago

Thanks Olivier .

1 0 0 0
1 year ago

I made a Starter Pack for the Myco & TB community.
Hope to find more good friends here on Bluesky to keep in touch about mycobacterial infections. Please join and repost!

go.bsky.app/3nwpcVV

80 38 32 7