Scott Wilcockson

Job alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk

Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️‍🩹

Full info below, and please share! 🫶🏻

bit.ly/467TO0M

I’m recruiting new members to the Farrell Lab this summer. We will have space for 1 postdoc (since Abhinav is leaving to start his own lab at U Arizona!!) and 2 postbacs, since my current two will leave for PhD programs at the end of the summer. More details in thread:

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis Live-imaging of a transgenic reporter of vascular Erk signalling in zebrafish reveals sequential signalling mechanisms during the initiation of regeneration in wounded blood vessels.

Also happy to help from the UK. @benjhogan.bsky.social and @kazebrafish.bsky.social previously generated a vascular-specific version using fli1aep. doi.org/10.7554/eLif...

🚨 Exciting opportunity for 🇨🇳 students!
Apply for a PhD scholarship via CSC to join my lab @UniofExeter studying cytoneme-mediated cell communication 🧫🐟

All projects are in collaboration with top Chinese universities: Tsinghua, Zhejiang & Kunming 🌏

📅 Deadline: 1 Dec 2025

携手探索细胞交流的奥秘，让科学没有距离！加油！💪🇨🇳✨

Deadline approaching – 15 Oct!
A brilliant PhD opportunity for all keen zebrafish enthusiasts, gene jockey and microscopy aficionados 🐟🧬🔬
If you find joy in embryos, lasers, and watching cells do clever things — this is your moment.

Inhibiting cytoneme formation prevents niche contact and BMP signal reactivation thus blocking germ cell dedifferentiation

A new in vitro model also illustrates how a source of BMP can promote cytoneme contact for signal activation

Now we have found that during germ cell dedifferentiation to reoccupy an empty niche, cytoneme formation becomes polarised toward the niche enabling access to stemness-promoting BMP signalling

Previously we showed that ovarian germ cells extend cytonemes and germline stem cells use these to probe their niche and access sequestered BMP

My first last 🥲 and the last of my 🪰 work (for now) with Catherine Sutcliffe, the Ashe lab, @hilary.ashe.bsky.social and @shukryjhabib.bsky.social.

www.pnas.org/doi/epdf/10....

Our work on germline stem cell cytonemes and BMP signalling is finally published! A great team effort from the Ashe lab, @wilcocksonscott.bsky.social and @shukryjhabib.bsky.social.

www.pnas.org/doi/epdf/10....

We are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics! @embl.org @embldbunit.bsky.social

Apply here:
embl.wd103.myworkdayjobs.com/EMBL/job/Hei...

Please re-post 🙏

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)

@wilcocksonscott.bsky.social kicks off the 9th Biosensor Workgroup meeting in Boulogne sur mer, France. ERK signaling in vivo coming up! #FRBiosensorMeeting

Award details | Funding and scholarships for students | University of Exeter

Are you an UK-based student and still looking for a PhD post in Life Sciences starting in autumn? Join the @lsiexeter.bsky.social - we have been awarded a few extra scholarships from the University. So, be quick and apply! www.exeter.ac.uk/study/fundin...

Interphase cell morphology defines the mode, symmetry, and outcome of mitosis During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity. We found that the shifts in cell morphology that shape tissues could conco...

My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...

The LSI Exeter invites you to join the first UK Zebrafish Meeting, 10/ - 12/9/ @lsiexeter.bsky.social. We are looking for motivated PhD students/ECRs to present their work - as talks and posters. www.exeter.ac.uk/research/ins... . The deadline for the early bird registration is 15/5/. So, be quick!

The 9th National Meeting of the #French #Fluorescent #Biosensor #Workgroup !

👉Registration deadline : May 30, 2025
👉Website : 9bgm.univ-littoral.fr

@france-bioimaging.bsky.social @sbcf.bsky.social @cnrs.fr
@fsipieter.bsky.social @wilcocksonscott.bsky.social
@kshkarina.bsky.social

#ULCO

We are hiring! A postdoc position is available in the lab studying gene expression dynamics in Drosophila embryos, as part of a larger research effort in collaboration with @mrattray.bsky.social 🧬🔬🪰

Full details are in the ad: www.jobs.manchester.ac.uk/Job/JobDetai...

Exploiting the SunTag system to study the developmental regulation of mRNA translation The ability to quantitatively study mRNA translation using SunTag imaging is transforming our understanding of the translation process. Here, we expand the SunTag method to study new aspects of transl...

Our new paper describes how SunTag imaging of mRNA translation can be used to study ribosome pausing in development. We also adapt the system to study translation of a secreted protein. Work done in collaboration with @mrattray.bsky.social and @markashe.bsky.social
doi.org/10.1242/jcs....

Is there more to defining the eve stripes in the Drosophila embryo than just transcriptional regulation? We provide evidence that spatially regulated mRNA decay is also important.

Still working on it, but now we are on bluesky I want to share our current preprint with you on"Local optogenetic NMYII activation within the zebrafish neural rod results in long range, asymmetric force propagation". www.biorxiv.org/content/10.1...

📢‼️ Exciting new preprint from the lab by @nikhil-mishra.bsky.social et al, now out on @biorxivpreprint.bsky.social, reveals that the early embryo geometry spatiotemporally patterns zygotic genome activation (ZGA) in zebrafish. 🐟 tinyurl.com/Biorxiv-nmis...

Read on to learn more... 👇

Applications open for a new cohort of @dev-journal.bsky.social *Pathway to Independence* fellows

Know a #devbio post-doc about to enter the academic job market?

Would they benefit from a little support & mentoring?

Spread the word

Deadline 31 Jan 2025

journals.biologists.com/dev/pages/pi...

We're hiring a postdoc! Please forward to people you know who are looking for positions.
Interested in studying how metabolism is wired to support fertility? 🔬🪰 Come join us!
Ad to go live next week, but informal enquiries encouraged.

Ovarian germline stem cell dedifferentiation is cytoneme-dependent Progenitor cell dedifferentiation is important for stem cell maintenance during tissue repair and age-related stem cell decline. Here, we use Drosophila ovarian germ cells as a model to study the role...

Welcome the Blue Exodus with a new preprint collab with my old gaff @mcf-uom.bsky.social @Ashelab

www.biorxiv.org/content/10.1...

Cytoneme-dependent BMP signalling promotes stem cell fitness and is necessary for dedifferentiation in the #Drosophila ovarian germline

First post, first Postdoc paper, first 🦓🐟 paper, first journal cover! 🥳

🎶On the fourth day of Christmas, Dev Cell gave to me: An improved Erk biosensor that detects oscillatory Erk dynamics driven by mitotic erasure during early development🎶

www.cell.com/developmenta...