Mass General Brigham Research

Mass General Brigham Research

@mgbresearch.bsky.social

The largest hospital-based #research network in the U.S. Where #science and #medicine converge to improve patient care. Blog: https://mgriblog.org We β€οΈπŸ”¬

380 Followers 43 Following 5 Posts Joined Nov 2024
2 weeks ago
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Scientists sharpen genetic maps to help pinpoint DNA changes that influence human health traits and disease risk By rapidly testing hundreds of thousands of DNA sequences, scientists have identified specific genetic variations that contribute to blood pressure, cholesterol, blood sugar, and more.

Pinpointing the exact noncoding variants driving locus-disease associations is an enduring challenge. Using MPRA, a @jacksonlab.bsky.social, Broad & @yaleschoolofmed.bsky.social team tested >220,000 variants in 5 cell types, resolving >13,000 and revealing mechanisms behind several disease traits.

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2 weeks ago
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Study reveals genetic balancing act between autoimmunity and cancer risk Researchers pinpoint genetic factors linked to both higher risk of a common autoimmune disorder and lower cancer risk

The same genetic variants that heighten the risk of autoimmune hypothyroidism β€” the most common autoimmune disorder β€” may also lower cancer risk, according to a new study led by scientists at Broad, @helsinki.fi, and @mgbresearch.bsky.social. broad.io/AIHT-news

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1 month ago
Research Spotlight: Discovering Risk Factors for Long-Term Relapse in Alcohol Use Disorder | Mass General Brigham Mass General Brigham researchers study risk factors of alcohol use disorder (AUD) and precursors to long-term relapse among individuals after one year of complete remission.

New research shines a light on why long-term relapse happens in alcohol use disorder, even after a year or more of sustained remission.

Read the full press release to learn how this work can change the way we think about relapse prevention: www.massgeneralbrigham.org/en/about/new...

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1 month ago

New publication on how researchers created AI-designed DNA ‡️

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1 month ago

A long engaging and amazing journey for me in Kidney Genetics !!

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1 month ago

In a new Cell Reports study, we examine a specific antibody family elicited by early COVID-19 vaccination and show how antibody maturation and binding diversity can allow some antibodies to remain effective against later variants, including Omicron. mgriblog.org/science-insi...

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4 months ago
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Genetic variant increases risk of heart muscle disease common in individuals of African ancestry A single mutation in the CD36 gene, present in 17 percent of people with African ancestry, increases a person's dilated cardiomyopathy risk by 33 percent.

A new @natgenet.nature.com study by Broad, @mgbresearch.bsky.social, and VA Boston collaborators reveals a genetic variant that helps explain the high dilated cardiomyopathy risk in people of African ancestry.

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4 months ago
Research Spotlight: Mapping How Gut Neurons Respond to Bacteria, Parasites and Food Allergy | Mass General Brigham The enteric nervous system is a vast network of nerves built into the walls of the intestine. A new study adds to accumulating evidence showing that the ENS works closely with the immune system to hel...

Great summary from the @mgbresearch.bsky.social team on our new Science paper about ENS–immune system interactions! Check it out: www.massgeneralbrigham.org/en/about/new...

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4 months ago
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In a new study, @shuimd.bsky.social and her colleagues in neonatology used electrical impedance technology (EIT) for a precision approach to optimize ventilator settings in infants with bronchopulmonary dysplasia.

Read more: www.nature.com/articles/s41...

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4 months ago
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Join us in congratulating three of our 2025 #DistinguishedInvestigators πŸ…!

These Investigators will be honored at a ceremony and celebration at #RSNA25 in Chicago. For more details, visit www.acadrad.org/wp-content/u.... @washumedicine.bsky.social @upenn.edu @mgbresearch.bsky.social

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4 months ago
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Join us in congratulating three of our 2025 #DistinguishedInvestigators πŸ…!

These Investigators will be honored at a ceremony and celebration at #RSNA25 in Chicago. For more details, visit www.acadrad.org/wp-content/u.... @ucirvine.bsky.social @mgbresearch.bsky.social

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4 months ago

Congrats to @connorjtou.bsky.social on being named a 2025 #STATWunderkind. His enthusiasm in the lab is contagious and he thrives on doing really hard things.
Really well deserved recognition for an innovator and emerging leader in our field! πŸ‘ πŸ™Œ
@mgbresearch.bsky.social @harvardmed.bsky.social

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4 months ago
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In a new study, researchers from Brigham and Women's Hospital and colleagues investigated the neuronal-activity dependent mechanisms of small cell lung cancer pathogenesis. The study was published on @nature.com

Read more: www.nature.com/articles/s41... @venkatesh-lab.bsky.social

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6 months ago
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In a new study, researchers from Mass General Brigham and colleagues found that the use of #AI ambient documentation tech significantly reduced physician burnout. The study was published in @jamanetworkopen.com.

Read more: www.massgeneralbrigham.org/en/about/new... jamanetwork.com/journals/jam...

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7 months ago
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The 2025 World Medical Innovation Forum is returning to Encore Boston Harbor from September 15-17! Join us as industry leaders and innovators come together to explore the most exciting breakthroughs shaping the future of healthcare.
Register now!: 2025.worldmedicalinnovation.org/register/
#WMIF2025

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6 months ago
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Three scientific projects from Brigham and Women's Hospital are competing for YOUR #vote in this year’s $100,000 Bright Futures Prize competition.

Cast your vote for the project you think should win, and register for the live event on 9/15:

www.discoverbrigham.org/funding/bri-...

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