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Kate Michie

@kmichie.bsky.social

Interested in Structural Biology, deep learning, NextFlow, HPC, viruses, missense mutations archaea, bacteria, evolution & random quirks of nature. (Protein Cosmos feed 🧢🧬) Leads a research group & Structural biology Facility,UNSW Sydney. Opinions my own.

2,671 Followers  |  929 Following  |  1,128 Posts  |  Joined: 30.08.2023
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Posts by Kate Michie (@kmichie.bsky.social)

Slide thanking the protein databank and all the researchers who contributed structures.

Slide thanking the protein databank and all the researchers who contributed structures.

At #bps2026 : I loved the special acknowledgement of the @rcsbpdb.bsky.social and the MANY researchers who generated the experimental macromolecular structures that made it possible to build AI models for structure prediction.

23.02.2026 20:44 β€” πŸ‘ 18    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

🀩🧢🧬

24.02.2026 08:13 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Dr Joshua Hamey - MACSYS Research Fellow
YouTube video by MACSYS Dr Joshua Hamey - MACSYS Research Fellow

Meet Dr Joshua Hamey, one of our outstanding MACSYS Research Fellows. Based at our UNSW node, Josh is a molecular biologist studying how proteins are made inside cells.
In this video, Josh shares insights into his research and what inspired him to join MACSYS.
youtu.be/MuAfPxFXWZk?...

18.02.2026 00:50 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Already more than 5,000 Australians have joined our campaign to release more funding for medical research in the 2026 Federal Budget.

If you can spare 30 seconds of your time to join our campaign, you’ll help fund life-saving cures in Australia.
www.moniqueryan.com.au/medical_rese...

19.02.2026 05:48 β€” πŸ‘ 81    πŸ” 32    πŸ’¬ 5    πŸ“Œ 4
Elitza Tochaeva presenting her work at UNSW today

Elitza Tochaeva presenting her work at UNSW today

Amazing talk today by Prof Elitza Tochaeva about the evolution of bacterial cell membrane and walls. Certainly got me thinking about bacterial and archaeal membranes. It is such a joy to see so many problems that are progressively being solved by Cryo ET. πŸ₯° 🧬🧢 @unswbabs.bsky.social

19.02.2026 08:50 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Super amazing work James!!! 🀩 Congratulations

19.02.2026 08:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Kinda smashing it right now. 🀩 Again- another great team effort with some superstars and some protostars (you know who you are πŸ˜‰)

19.02.2026 08:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ˜‚ I hear you.

19.02.2026 01:31 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I get it-but these little guys are hard to keep alive. They evolved when our world was really different. They live in weird places that you certainly wouldn’t. Studying them helps us understand how to treat diseases and make new drugs. Try to think happy thoughts when you see them-they don’t hurt us

18.02.2026 21:35 β€” πŸ‘ 31    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

More importantly, this linage of archaea is currently the closest we know of that marks the point that complex organisms diverged. Most of the complex systems in our own bodies are found in this organism. You are looking at a cousin here people.

18.02.2026 21:20 β€” πŸ‘ 70    πŸ” 9    πŸ’¬ 2    πŸ“Œ 0

So nice to see this story! Jan is like a dog with a bone chasing this down. The origin of alpha/beta tubulins has been a question he won’t let go of. Great collaborative team effort and careful work. Recommended 🧬🧢

16.02.2026 21:47 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Beautiful work Deb! Check out these structures? Biofilms are very interesting. 🧢🧬

12.02.2026 19:39 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Dr Tom Litfin (Australian Biocommons) presented the Structural Biology Platform project and the Australian Computational Structural biology community. If you are interested and missed him you can join up here: australian-structural-biology-computing.github.io/index
🧬🧢 #lorneprotein2026

11.02.2026 00:54 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

🧢🧬

10.02.2026 22:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Be part of Lorne Proteins history! Photo session today from 1-1:10 pm. See you there πŸŽ‰πŸ“·πŸ€©

#lorneproteins2026

10.02.2026 22:17 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Slide of retromer-rab7 complex from Kevin’s presentation at Lorne Proteins 2026

Slide of retromer-rab7 complex from Kevin’s presentation at Lorne Proteins 2026

Beautiful structural work on the Retromer-Rab7 complex presented by Kai-En Chen at Lorne Proteins. Also a preprint:https://www.biorxiv.org/content/10.64898/2026.01.23.701266v2
#lorneprotein2026

10.02.2026 22:36 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

This was a beautiful talk.

10.02.2026 22:17 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Just a few hours before Lorne Protein kicks off! Exciting line-up, gorgeous location. See you there. 🧬🧢

08.02.2026 01:26 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Assessing the validity of leucine zipper constructs predicted by AlphaFold AP-1 transcription factors are a network of cellular regulators that combine in different dimer pairs to control a range of pathways involved in differentiation, growth, and cell death. They dimerize...

This was interesting and fun to do… seems Alphafold and the like have learnt what a Leucine zipper looks like… but not really.πŸ€” interesting that a fully synthetic leucine zipper that couldn’t possibly assemble looked pretty probable. 🧢🧬

doi.org/10.1002/pro....

23.12.2025 22:39 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Oh yeah… can do that.

08.12.2025 08:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Diagram describing the change in process of PBD submissions from Oceania in 2026- now going via PDBj

Diagram describing the change in process of PBD submissions from Oceania in 2026- now going via PDBj

Hey structural biologists submitting PDB’s from Oceania in 2026…. Keep those structures coming via the Japanese PDB node! 🀩

08.12.2025 06:00 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Lots of fun delivering a talk about how to use structural predictions in biological research to Perth Protein Group yearly meeting. Perth is lovely! Wish I could have stayed longer. Great to see old friends and meet some new ones #perthproteins

28.11.2025 07:30 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wow! That’s rather embarrassing not to be there for that ( sorry about that- I’m mid-air -almost in Perth for a talk at the protein meeting tomorrow) and rather humbling as well. πŸ™

26.11.2025 11:15 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It was a great meeting! Highly recommended. Sorry to have missed the last and best part- all those amazing early career speakers and poster prizes!!! Congratulations everyone. Wonderful job to the organisers.

26.11.2025 10:56 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Celebrating the scientific legacy of Shin-Ho Chung to #biophysics at the @aus-soc-biophys.bsky.social meeting #ASB2025 on the Gold Coast with excellent presentations by Toby Allen, Ben Corry, Evelyne Deplazes, Elaine Tao, Jennifer Deuis, and @ciarawallis.bsky.social

25.11.2025 14:03 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Hearty congratulations to Assoc. Prof. Matthew Baker @phatmattbaker.bsky.social who was awarded the MacAulay-Hope Prize for originality and innovation in #biophysics at the @aus-soc-biophys.bsky.social meeting #ASB2025 at Griffith University Gold Coast campus.

25.11.2025 14:36 β€” πŸ‘ 16    πŸ” 6    πŸ’¬ 2    πŸ“Œ 0
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LMI4Boltz: Optimizing VRAM utilization to predict large macromolecular complexes with consumer grade hardware AlphaFold2 has revolutionised structural biology by enabling the prediction of protein structures approaching experimental quality. AlphaFold3 extends this framework to support modelling broad biomole...

Follow Tom here: @tlitfin.bsky.social

And preprint: www.biorxiv.org/content/10.1...

26.11.2025 03:19 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

🀩 I’m biased but… so sorry to have missed this.

26.11.2025 03:14 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Research Management System - Scheme Round Statistics for Approved Applications - Discovery Early Career Researcher Award 2026 round 1 RMS is the ARC's Research Management System, a web-based system used by eligible researchers to prepare and submit research proposals and assessments under the ARC National Competitive Grants Program ...

DECRAs are out! Good luck young investigators. If you are unlucky- please don't let this moment define you.
#ARC

25.11.2025 00:15 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Registration for #APSPM2026 closes soon.

Everyone’s welcome! whether you study evolution, structure, or computational methods, join us in Brisbane (and online) Feb 16–18, 2026 to learn how protein structure meets phylogenetics.
biosig.lab.uq.edu.au/strphy26

@official-smbe.bsky.social

23.11.2025 22:03 β€” πŸ‘ 7    πŸ” 7    πŸ’¬ 0    πŸ“Œ 2