Are you fascinated by self-organised patterning processes?
The brand-new Stuart lab at EMBL Barcelona is looking for a lab manager!
Hannah @htstuart.bsky.social is a fantastic scientist and mentor. Building the lab with her will be a lot of fun!
embl.wd103.myworkdayjobs.com/EMBL/job/Bar...
New Perspective form Rory Maizels & me: "Gene regulatory networks: from correlative models to causal explanations"
Gene regulatory networks are supposed to give us mechanistic explanations of development, so why are we drowning in 'hairballs' of statistical correlations?
rdcu.be/e7zx7
Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).
A brief 🧵 (carried over from the old place)
Please check out our new preprint! Using single cell analysis paired with HCR to visualize transcript localization we have identified cell and tissue-specific expression of various genes encoding tubulins, kifs, and dyneins during neural crest development!
Finally I can join #FluorescenceFriday as a theorist 😊.
This is a DNA-PAINT recording of E-Cadherin and F-actin in Drosophila embryonic epidermis. You can see E-cadherin clusters and their counterparts across junctions. Cover in @biophysj.bsky.social . doi.org/10.1016/j.bp... #devbio #cellbio
New preprint from Meri Saez & co
How much information does a developmental landscape encode?
Integrating information theory, dynamical systems & dev bio to quantify the number of signalling regimes that generate distinguishable cell fates
biorxiv.org/content/10.64898/2026.03.03.709461v1
🚨 New Preprint from the Paluch & Chalut Labs 🚨
Ana Raffaelli et al show that the stiffness of substrate (in vitro) / basal membrane (in vivo) determine how cells interpret biochemical signals (BMP4) and which fates they acquire
#mechanobiology #hESCs #substratemechanics
doi.org/10.64898/202...
🚨3-year Postdoc Position @halloulab.bsky.social (Kennedy Institute, Oxford) - on Spatial Biology & Bioinformatics of Fibrosis🚨
An exciting project combining #SpatialTranscriptomics & #Mechanobiology👇:
shorturl.at/LLS5r
Deadline: 16 March - Please RT 📢!
@kiroxford.bsky.social @ox.ac.uk
Here's the link to the original article if you haven't checked it out already! www.nature.com/articles/s41...
How moss makes a spiral of leaves through a rotating asymmetric division of the apical cell meristem--our paper is out @currentbiology.bsky.social today! @soestrauss.bsky.social Richard Smith, Joe Cammarata
www.cell.com/current-biol...
1 year ago at the @standupforscience.bsky.social rally, scientists, students, advocates, & community members joined in cities nationwide. Now we're returning to the streets in nearly 30 cities & towns o demand scientific integrity, strong public health protections, & democratic accountability 1/n
In our latest preprint we show that Lifeact::mKate2 can reverse the chirality of active torques in the actomyosin cortex. This results in cortical flows with opposite handedness during left-right symmetry breaking, leading to the formation of situs inversus worms.
www.biorxiv.org/content/10.6...
Send us your stem cell manuscripts! Very easy to transfer from biorxiv and we can also quickly consider a manuscript based on reviews received elsewhere. JCS does a tremendous job of supporting the scientific community (see the link below). Reach out if you have questions!
Registration is OPEN for the 2026 Santa Cruz Meeting on Developmental Biology!!! Please spread the word!
@mads100tist.bsky.social @socdevbio.bsky.social @bsdb.bsky.social @xenbase.bsky.social @isdb.bsky.social @devbiol.bsky.social @the-node.bsky.social
scdb2026.sites.ucsc.edu
Are you working on stem cell biology? Our Academic Editor Aryeh Warmflash (@warmflashlab.bsky.social) is committed to handling articles on this topic so send your article our way.
There are lots of reasons to choose JCS – find out more: journals.biologists.com/jcs/pages/re...
#stemcells
New from us in @pnas.org :
We considered the limits of condensate diversity, and engineered DNA droplets to form 9 distinct, homotypic, coexisting phases. Very hard to do this except with nucleic acids. Probably you can make more than 9. (1/3)
We summarised the many roles of material phase transitions in development (and they are not just mechanical 🤔)
Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development!
@karengrace12.bsky.social @nicolettapetridou.bsky.social
🔗 doi.org/10.1242/dev....
New preprint @biorxiv-devbio.bsky.social by Harshath Amal and colleagues from our lab @uni-muenster.de shows how a BMP #morphogen gradient is translated into graded junctional permeability by tuning adhesion and actomyosin contractility in #Drosophila
See tinyurl.com/yhbwd9xh
@sfb1348.bsky.social
We‘re looking for a motivated Master student to join our team!
Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬
Then please apply!
#optogenetics #metabolism #devbio #hESCs
Please RT. Thank you!🙏
For those interested! Speakers include @dianapinheiro.bsky.social, @ritamateus.bsky.social & @streichan.bsky.social 🐟
A Postdoctoral Associate position is available in the Roeder Laboratory at Cornell University in Ithaca, NY with a focus on researching Polyploidy. Apply by March 1. Please spread the word. apps.hr.cornell.edu/recruiting/f...
Our latest with @torres-sanchez.bsky.social journals.biologists.com/dev/article-...
Breaking isn’t always a bad thing! Think of birth, seed release...
We highlight how living tissue not only tolerates fractures but actively fracture to grow, shape, reproduce, or adapt – across species and scales.
Very interesting study from the Schweisguth lab - Pulsatile dynamics propagate crystalline order in the developing Drosophila eye: Developmental Cell www.cell.com/developmenta...
After being reviewed as a preprint in Elife our paper about endogenous FGF signaling in 2D human gastruloids is now published in Development:
journals.biologists.com/dev/article-...
Postdoc position available!!! We are looking for a creative postdoc to develop independent research directions in tissue morphogenesis using embryos, stem cell/organoid systems, and quantitative imaging and/or biophysics. Here are the details: livejohnshopkins-my.sharepoint.com/:b:/g/person...
El Paso is my hometown, and my birthday happens to be this week. Please join me in donating to Annunciation House (annunciationhouse.org). They help migrants, immigrants, and refugees in El Paso. More recently, they've sheltered people released from ICE detention: www.elpasotimes.com/story/news/i...
Instructors include @akankshi.bsky.social, @nicolettapetridou.bsky.social, @dianapinheiro.bsky.social, @chloeroffay.bsky.social, & @streichan.bsky.social among others! 🐟
Seconded. If anything, it has never been a better time to be a biophysicist, a complex system physicists, etc…. And it is a bit sad that much of it now happens *outside* of physics departments (for good and bad reasons…)
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.
Stay free