Open Medicine Foundation (OMF)

OMF graphic recognizing National Caregivers Day on February 20.

OMF honors and recognizes the dedication of caregivers who provide daily support, advocacy, and stand beside loved ones living with #MECFS, #LongCOVID, and related diseases.

To every caregiver: thank you. You make a difference. You matter.💙

A professionally designed title slide with a dark blue, abstract background featuring glowing light-blue nodes connected by thin lines. Centered in the lower half is a large light gray rectangular overlay containing the title in bold black text: “A chronobiology-based protocol for multi-omic mapping of menstrual cycle and diurnal rhythms in ME/CFS and long COVID”

In Case You Missed It: A newly published protocol in npj Women's Health introduces the MELLOW study, a global collaboration between OMF’s Melbourne and Uppsala teams.

🔗 Read the full protocol: https://ow.ly/pJlC50Y0new.

The image shows an orange prescription pill bottle tipped on its side, with small white round tablets spilling out onto a light blue surface.

Dose titration is the process of gradually changing (titrating) the dose of a drug to get the best effect while minimizing side effects.

Learn more about dose titration and OMF's Life Improvement Trial (LIFT): https://www.omf.ngo/dose-titration/

A professional portrait of Dr. Armstrong in an office setting, alongside text announcing nearly $1M awarded to the OMF Melbourne ME/CFS Collaboration.

Dr. Christopher Armstrong and his team at OMF's Melbourne ME/CFS Collaboration have been awarded nearly $1 million through the Australian government’s Medical Research Future Fund (MRFF) for the project Energy inefficiency in #LongCOVID and #MECFS.

👉 Learn more: https://ow.ly/hj9F50Yh6TY

This image is a reminder note addressed to the "OMF Community." It is dated February 14, 2026. The message expresses admiration and support, stating: "You are strong, you are resilient, and you are worthy of all the love. Today, we celebrate you and the strength you show every day."

Reminder: Today, we celebrate you and the strength you show every day. You are strong, you are resilient, and you are not alone. 💙

Brief description: double-blind, placebo-controlled investigation of pyridostigmine (Mestinon) and low dose naltrexone (LDN)

Time required: 3 months, 3 onsite visits, 4 virtual visits

Study tasks: sub-maximal exercise test(s), biweekly questionnaires and brain games, blood draws

On the right, eligibility criteria are listed: ages 18–65, meet Canadian Consensus Criteria for ME/CFS with orthostatic intolerance, symptom onset before December 2023, ability to meet study requirements, and possession of a functioning smartphone. Below, text invites participation through OMF’s StudyME Registry at www.omf.ngo/studyme

The Mestinon/LDN Life Improvement Trial (LIFT) is seeking eligible research participants now within 300 miles of Brigham and Women’s Hospital at Harvard Medical School.

Learn more about the LIFT: https://clinicaltrials.gov/study/NCT06366724

A close-up photo shows hands stacked together, symbolizing unity, support, and compassion. The background is a soft, blurred green. Overlaid text reads “Annual Report 2025. The OMF logo is at the bottom.

Because of our incredible community, 2025 was a year of meaningful progress.

We’re proud to share our 2025 Annual Report, highlighting the milestones we reached together and the momentum we’re building for the year ahead. 🤝

🔗 2025 Annual Report: https://www.omf.ngo/2025-achievements/.

Healthcare provider writing on a chart, with a stethoscope and various pills and medicines visible in front of him. The text reads: “Science Wednesdays, Precision Medicine.”

Precision medicine is a way of treating a disease differently based on a person’s symptoms, genes, environment, or other factors.

Learn more about precision medicine and OMF’s Melbourne Collaboration project: https://www.omf.ngo/what-is-precision-medicine/

Promotional graphic for the StudyME Registry. The background shows blurred researchers working in a lab. Text on a white banner at the bottom reads: “Do you want to help speed up the research process? Now you can! Join the OMF StudyME Registry: www.omf.ngo/studyme.”

🔬Help advance #MECFS and #LongCOVID research by joining OMF’s StudyME, a free global participant registry that connects you with researchers conducting studies in these areas. Healthy volunteers are needed too!

👉 Sign up today: https://www.omf.ngo/studyme/

We’re releasing a new State-by-State Resource Directory to help people living with ME/CFS and other disabling chronic illnesses find local and national support.

Free, practical, and built for real life.
🔗https://bit.ly/3ZBBIAC

Dr. Alain Moreau wearing a suit and pointing at a scientific poster. The text reads: “Science Wednesdays: Phenotype”

A #phenotype is an observable characteristic (e.g., physical trait, presence of disease), and it is determined by the interaction of a person’s #genotype (genetic makeup) and their environment.

Learn more about phenotype: https://www.omf.ngo/phenotype/

At the bottom is a picture of Wenzhong Xiao, Alain Moreau, Ron Davis, Chris Armstrong, David Systrom, Jonas Bergquist, Linda Tannenbaum, and Maureen Hanson. The text reads: “Don’t miss a thing, sign up for our newsletter.”

Get the latest on OMF research in 2026.

➡️ Add impact to your inbox! Subscribe to OMF newsletter 👉 https://ow.ly/w0TO50WwRs4

🌟 When you subscribe, you’ll get the latest on OMF research, announcements, campaigns, and more—delivered straight to your inbox.

#pwME #MECFS #LongCOVID #pwLC #OMFResearch

From the OMF-Supported Medical Education Resource Center (MERC) with @batemanhornecenter.bsky.social

Close-up of a stethoscope beside a red heart-shaped model on top of a medical chart. The text reads: Science Wednesdays: Retrospective vs prospective study.

A retrospective study is one that is conducted on existing data, in contrast to a prospective study that actively collects data. In #MECFS research, both retrospective and prospective studies are important.

👉 Read more: https://www.omf.ngo/retrospective-vs-prospective-study/

A healthcare professional wearing a white coat holds a stethoscope. On the left side of the image are the VuMedi logo and the OMF logo, representing collaboration.

🩺 Share OMF’s VuMedi channel with your healthcare professional: https://ow.ly/CFVu50Y4lpZ

OMF’s expert-led channel features research-informed videos on #MECFS, #LongCOVID & related conditions to support evidence-informed care. Access limited to licensed healthcare providers.

Photo of computer with a telehealth graphic on the screen in center of graphic. Text above: Breaking News. The House passed Medicare telehealth flexibilities extension- on to the Senate! Text underneath: Medicare telehealth flexibilities would be extended by two years, until Dec. 31, 2027. The bill is now headed to the Senate for a vote before the Jan. 30th deadline

TELEHEALTH UPDATE: The House passed the Department of Health and Human Services’ funding bill yesterday, including telehealth extensions.
Under the proposal, Medicare telehealth flexibilities would be extended by 2 years, until Dec. 31, 2027. They are not permanent so there is still work to be done.

Graphic showing three researcher portraits: Dr. Christopher Armstrong, Dr. Natalie Thomas, and Dr. Jonas Bergquist, with the title “A chronobiology-based protocol for multi-omic mapping of menstrual cycle and diurnal rhythms in ME/CFS and long COVID.”

A newly published protocol in npj Women's Health introduces the MELLOW study, a global collaboration between OMF’s Melbourne and Uppsala teams.

🔗 Read the full protocol: https://www.nature.com/articles/s44294-025-00120-9.

#WomensHealth #MECFS #LongCOVID #CircadianRhythm #HormoneResearch

👉 Explore OMF’s channel: www.vumedi.com/channel/open...

🔗 VuMedi is free for healthcare professionals and designed to support lifelong learning across specialities. Register for VuMedi: www.vumedi.com/accounts/log...

Vumedi and Open Medicine Foundation (OMF) logos on a white background with an abstract network of connected dots and lines, representing collaboration and scientific research.

OMF is proud to partner with Vumedi, a global education platform for healthcare professionals, to bridge research and clinical practice.

Our expert-led content on #MECFS, #LongCOVID, and related diseases is now live—helping clinicians worldwide stay up to date with evidence-based learning.

A close-up view of the Martin Luther King Jr. Memorial in Washington, D.C.White serif text overlays the image with the quote: “Out of the mountain of despair, a stone of hope.” The attribution “Martin Luther King Jr.” appears in the lower right corner.

“Out of a mountain of despair, a stone of hope.” — Martin Luther King Jr.

Today, we honor the life and legacy of Dr. Martin Luther King Jr. His words continue to remind us to hold on to hope. #MLKDay

Graphic with the title “Shop with Purpose!” showing a phone with a shopping cart image and OMF logo. Steps on the right: Visit iGive (bit.ly/iGiveOMF), Sign up for a free account, Shop online — a percentage goes to OMF.

🛍️ Imagine if every item you added to your cart could help fuel OMF's vital #MECFS and #LongCOVID research.

With iGive, you can shop online at 1,700+ stores, and a percentage of your purchase will go to OMF, at no extra cost to you.

Shop & Support 👉 www.igive.com/welcome/lp19....

Graphic titled “Reading Scientific Papers”. A person wearing a white lab coat sits at a desk, holding a blue pen and reviewing printed research papers. A blue button reads “Science Wednesdays.”

📑 Scientific papers typically include: abstract, introduction, methods, results & discussion. TIP: use the abstract, look at the figures for the results, form your own conclusion, then read the discussion.

👉 Reading scientific papers: www.omf.ngo/scientific-p...

Large text reads, 'INSIDE OMF: YOUR QUESTIONS, OUR ANSWERS.' There are two photos: on the left is Linda Tannenbaum smiling, and on the right is Danielle Meadows, also smiling.

On January 21 at 1:00pm ET, Linda Tannenbaum (CEO and Founder) and Danielle Meadows, PhD (VP of Research Programs) will host a webinar with the objective of answering your questions about OMF and its research.

Register for the webinar: ow.ly/IyGz50XWboB
Submit question: ow.ly/81OM50XWboA

On the left, a light blue background with bold navy text reads “OUT WITH THE OLD.” Below, smaller text says, “Give your car a new purpose this January.” A teal button reads “Donate Your Vehicle”. On the right, a dusty, older silver car is parked in a dark garage.

Give your car new purpose! 🚙

When you donate your car, truck, motorcycle, RV, or boat to OMF, the proceeds from your sale will support #MECFS and #LongCOVID research.

👉To learn more, visit: careasy.org/nonprofit/Op....

Science Wednesdays graphic showing a clinician with a stethoscope holding a glowing human silhouette over a connected network; text reads “Symptom Burden.”

OMF’s team incorporates symptom burden into the portfolio of work in a variety of ways, spanning different methods of assessing function to analysis that clusters participants based on symptom burden.

Learn more about symptom burden and OMF's projects: www.omf.ngo/symptom-burd...

The background shows two researchers in lab coats and safety goggles working with microscopes and lab equipment. In the center, a dark blue box contains the text: “Newsletter – Stay updated on ME/CFS & Long COVID research.” Below the box is a white button with the text: “Subscribe to our newsletter.”

➡️ Add impact to your inbox! Subscribe to OMF newsletter 👉 ow.ly/w0TO50WwRs4

🌟When you subscribe, you’ll get the latest on OMF research, announcements, campaigns, and more.. Your information is kept private, and you can unsubscribe anytime.

#pwME #MECFS #LongCOVID #pwLC

A hand holding a paper labeled “Hope” in sunlight, with text reading “End the year with hope. Last chance to make a difference in 2025,” and OMF branding.

With just a few hours left in 2025, you have a unique opportunity to make a difference with a year-end gift. 🔗Donate now: www.omf.ngo?form=donatenow

ICYMI: Director interviews, OMF Journal Club, Science Wednesdays & an upcoming community webinar: www.omf.ngo/year-end-202....

Blue-toned lab image with a microscope and glassware. The OMF Hope logo appears in the top left, and a banner reads “2025 Publications and Preprints.”

⏳ Only 2 Days Left to Donate in 2025! 👉 Donate today: ow.ly/jNMx50XQmj6.

As 2025 draws to a close, we want to take a moment to reflect on the progress we’ve made together.🔬 Check out our 2025 Publications and Preprint Overview: ow.ly/YTQT50XQmj4.

Key highlights from 2025: 40 active research projects underway; 16 new scientific publications and one preprint; StudyME registry with over 14,500 participants supporting 21 studies worldwide; launch of BioQuest, the largest biomarker discovery study in ME/CFS research; progress in the Life Improvement Trial (LIFT); and release of a Clinical Care Guide for ME/CFS and Long COVID through the Medical Education Resource Center.

Because of our community, 2025 moved the field forward. Since 2012: $60M+ raised, 76 projects, 53 publications.

With just a few days left in 2025, will you consider making a gift? A year-end gift keeps research moving. Donate hope today👉 www.omf.ngo?form=donatenow