Chris Anderton ⚜️

It has been an amazing journey to publish this work on ES&T about #microbial_necromass🐛🦠🪱.

Accumulation of Soil Microbial Necromass Controlled by Microbe–Mineral Interactions | Environmental Science & Technology pubs.acs.org/doi/10.1021/...

Hey 👋 all! It’s been awhile!

Anyway, our team has a new PD opening: Carbohydrate and Glycan Imaging Scientist in Richland, Washington. Review all of the job details and apply today! careers.pnnl.gov/jobs/10838?lan… @imsis-americas.bsky.social @asms.org

At ASMS? Stop by the Imagers Happy Hour before the Opening Plenary!
📍 Pickles Pub, Baltimore
🕓 Sun June 1 | 4–6:30pm
🎯 Right after the Users Meeting
Hosted by IMSIS-Americas
#ASMS2025 #MSI #IMSIS

IMSIS 3 is happening Sept 29–Oct 2, 2025 at UC Davis!
Join us From Micro to Macro and Beyond 🧬
Registration now open: imsis3.msimaging.science/en/registration-form
Talks, posters, wine, and cows.
#IMSIS2025 #MSI #MassSpec #ASMS2025

Imaging and spatially resolved mass spectrometry applications in nephrology - Nature Reviews Nephrology In this Review, the authors discuss mass spectrometry (MS) imaging and spatially resolved MS approaches that are being employed in nephrology applications. They also highlight emerging MS methods and ...

Super happy to share our new review in Nature Reviews Nephrology: www.nature.com/articles/s41... @kpmproject.bsky.social @beesgees.bsky.social @imsis-americas.bsky.social

The Impact of the Mass Analyzer and Tissue Section Thickness on Spatial N-Glycomics with MALDI-MSI We compared matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) spatial N-glycomics data sets from Fourier-transform ion cyclotron resonance (FTICR) and orthogonal accele...

Check out our paper in @jasms.bsky.social ! The Impact of the Mass Analyzer and Tissue Section Thickness on Spatial N-Glycomics with MALDI-MSI. 🥁Imaging N-glycans on 2 µm FFPE sections, ideal for pathologist! 🥼 @imsis-americas.bsky.social pubs.acs.org/doi/full/10....

Registration is open for Part II of the PCA Spatial Metabolomics Workshop! Join us on March 5 with our hosts Chris Anderton (@anderton.bsky.social) and Aleksandra Skirycz. For more information and to register for this workshop, visit the website: bit.ly/4hOE4Dm

Excited to be hosting Part II of the Plant Cell Atlas Spatial Metabolomics ​Workshop in March. It's a FREE virtual workshop. Please sign up if interested. @plantcellatlas.bsky.social www.plantcellatlas.org/pcametaworks...

✨ Fernando “Ralph” Tobias @ftobias.bsky.social – Secretary

✨ Boone Prentice @prenticelabuf.bsky.social – Counselor

✨ Jillian Johnson – Counselor

#IMSIS #MassSpecImaging #MSI #SpatialOmics #MassSpectrometry #ScienceLeadership #AnalyticalChemistry #TeamMassSpec

Untargeted Spatial Metabolomics and Spatial Proteomics on the Same Tissue Section An increasing number of spatial multiomic workflows have recently been developed. Some of these approaches have leveraged initial mass spectrometry imaging (MSI)-based spatial metabolomics to inform the region of interest (ROI) selection for downstream spatial proteomics. However, these workflows have been limited by varied substrate requirements between modalities or have required analyzing serial sections (i.e., one section per modality). To mitigate these issues, we present a new multiomic workflow that uses desorption electrospray ionization (DESI)-MSI to identify representative spatial metabolite patterns on-tissue prior to spatial proteomic analyses on the same tissue section. This workflow is demonstrated here with a model mammalian tissue (coronal rat brain section) mounted on a poly(ethylene naphthalate)-membrane slide. Initial DESI-MSI resulted in 160 annotations (SwissLipids) within the METASPACE platform (≤20% false discovery rate). A segmentation map from the annotated ion images informed the downstream ROI selection for spatial proteomics characterization from the same sample. The unspecific substrate requirements and minimal sample disruption inherent to DESI-MSI allowed for an optimized, downstream spatial proteomics assay, resulting in 3888 ± 240 to 4717 ± 48 proteins being confidently directed per ROI (200 μm × 200 μm). Finally, we demonstrate the integration of multiomic information, where we found ceramide localization to be correlated with SMPD3 abundance (ceramide synthesis protein), and we also utilized protein abundance to resolve metabolite isomeric ambiguity. Overall, the integration of DESI-MSI into the multiomic workflow allows for complementary spatial- and molecular-level information to be achieved from optimized implementations of each MS assay inherent to the workflow itself.

Single tissue untargeted multiomics? Yes, please! Our new paper is now online. @pnnl.bsky.social @bindesh1.bsky.social @imsis-americas.bsky.social
pubs.acs.org/doi/10.1021/...

Post Doctorate RA - Spatial Glycomics Scientist in Richland, Washington | Pacific Northwest National Laboratory PNNL is hiring a Post Doctorate RA - Spatial Glycomics Scientist in Richland, Washington. Review all of the job details and apply today!

Interested in spatial biology #TeamMassSpec? Experienced in #glycotime?

Check out this add my colleague Dušan posted for a postdoc here at PNNL. A really amazing opportunity to work with a great team, please share!

@chemjobber.bsky.social #chempostdoc

careers.pnnl.gov/jobs/10140?l...

The promising role of proteomes and metabolomes in defining the single‐cell landscapes of plants The plant community has a strong track record of RNA sequencing technology deployment, which combined with the recent advent of spatial platforms (e.g. 10× genomics) has resulted in an explosion of s...

@uhriglab.bsky.social and my new Viewpoint is now published in @newphyt.bsky.social on behalf of the Plant Cell Atlas! nph.onlinelibrary.wiley.com/doi/10.1111/...

Off to EMSL to visit @anderton.bsky.social 🤓 nerd time with all the fancy instruments and microbial community work! Wondering if the Tricities are close enough to still find good Walla walla tacos… #MassSpectacular

a man says i 'm getting too old for this peacock advertisement ALT: a man says i 'm getting too old for this peacock advertisement

Okay so we’re here now? No longer on the wasteland that killed the bird? I’m not sure I can do another social media platform after this!

Packed house at IMSIS2023!

Ready for the first ever #IMSIS Annual Conference #IMSIS23! Mass spectrometry imaging— at the international scale! Also, they have good poutine in Montreal, eh?

Photo of group enjoying coffee break at the ASMS Asilomar Conference on Computational Mass Spectrometry.

Enjoying morning coffee at the @asms.org Asilomar Conf on Computational Mass Spec in beautiful Pacific Grove, CA.

Lively Q&A's + generous break time are generating the desired interactions among #TeamMassSpec attendees. Love it!

Looking forward to what's up next: www.asms.org/conferences/...