Ivano Amelio

I am very much looking forward to joining and contributing to the DNA Repair Meeting 2026. 🧬🧬

Submit an abstract and join us in Cologne this September: express.converia.de/frontend/ind...

Congrats!!! 🥂

Hidden struggles: Cambridge scientists share the truth behind their success In a career defined by constant questioning, self-doubt can become an occupational hazard. Now, for the first time, a group of Cambridge scientists reveal the personal struggles they’ve faced – and co...

“I find it amazing to see such high-performing people struggling with self-doubt. Every successful scientist I know has a lifetime of failure behind them, even if those parts of their story are rarely on display.” [Professor Adrian Liston, University of Cambridge]

www.cam.ac.uk/stories/camb...

Let's start the New Year with this reminder.
Let's stay curious!!! 😊
Happy New Year!!! 🥂

Winter sunset over Meinau and the Bodensee

Introducing the j-metric: a true measure of what matters in academia Science has become obsessed with publishing numbers. With this new satirical proposal, have we reached peak metric?

"... academia becomes McDonaldized — subject to the fast-food industry principles of efficiency, calculability, predictability and control — ..."
@nature.com

www.nature.com/articles/d41...

ZAK activation at the collided ribosome - Nature The kinase ZAK is activated at collided ribosomes to mediate the ribotoxic stress response.

www.nature.com/articles/s41...

something new, preprint + ai review ✅

Magic in Crete ✨

Nothing beats this conference... ideas flowing, connections sparking, and the kindest people all around 🌊☀️

The Scientific Drunk and the Lamppost: Massive Sequencing Efforts in Cancer Discovery and Treatment Signaling networks may provide greater return for the investment in cancer research.

www.science.org/doi/10.1126/...

A fantastic viewpoint by @frezzalab.bsky.social network.febs.org/posts/thinki...

It reminds me of the lampost-and-key analogy described in this article by Michael Yaffe www.science.org/doi/10.1126/....
The goal is to understand network-based signalling.

👉 Check it out and join the movement

Universities are — and must continue to be — a force for good From funding squeezes to political attacks, higher education is in trouble in many parts of the world. Fresh ideas will allow the sector to thrive and deliver value for society.

Universities generate ideas and knowledge, for long-term societal progress, not short-term metrics.

"Universities are — and must continue to be — a force for good. Fresh ideas will allow the sector to thrive and deliver value for society."
@nature.com

www.nature.com/articles/d41...

It was a fantastic Swiss Apoptosis Meeting.
Great science and nice colleagues as usual.

This time this view of the Swiss Alps from Bern to Konstanz was a plus.

Moonlight. Bodensee. Silence. ✨

⏳ Just 3 days left! Don’t miss the chance to present your science at #ECDO2025 in Berlin.

Submit your abstract today 👉 www.ecdo.eu/ecdo2025/con...

#CellDeath #Berlin2025

Congrats to ‪@linkermannlab.bsky.social‬ on this important work highlighting the role of sex hormones in regulating susceptibility to ferroptosis.

... and welcome on Bleusky, btw.

Register to the ECDO-2025 in Berlin!!!

Registration is on a first come, first served basis, so we highly recommend securing your spot as soon as possible.
Join us in Berlin for an unforgettable event.

We can’t wait to welcome you to ECDO-2025! 🌍🎓

Very proud on our stellar Alina Ritter for her frist first-author paper:

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances #chemotherapy efficacy in #Ewing #sarcoma

tinyurl.com/3kcs3bc9

@dkfz.bsky.social
@uniheidelberg.bsky.social
@nct-heidelberg.bsky.social

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances chemotherapy efficacy in Ewing sarcoma Distant metastasis is the leading cause of mortality in Ewing sarcoma (EwS) -a malignant bone or soft-tissue cancer mainly affecting children, adolescents, and young adults. Despite continuous efforts...

Congratulations @grunewaldlab.bsky.social team for another impressive work...

www.biorxiv.org/content/10.1...

Aberrant basal cell clonal dynamics shape early lung carcinogenesis Preinvasive squamous lung lesions are precursors of lung squamous cell carcinoma (LUSC). The cellular events underlying lesion formation are unknown. Using a carcinogen-induced model of LUSC with no a...

www.science.org/doi/10.1126/...

Delving into LLM-assisted writing in biomedical publications through excess vocabulary Excess words track LLM usage in biomedical publications.

"This excess word analysis suggests that at least 13.5% of 2024 abstracts were processed with LLMs. This lower bound differed across disciplines, countries, and journals, reaching 40% for some subcorpora"

www.science.org/doi/10.1126/...

Neuronal transfer of mitochondria to tumour cells promotes cancer spread Neurons often receive organelles called mitochondria from other cells. It emerges that neurons donate mitochondria that support cancer-cell spread.

Neurons often receive mitochondria from other cells, supporting cancer cell spread

https://go.nature.com/3ZLBhnV

Register now for the 7th German-French DNA Repair Meeting, which will take place at the Campus Pierre et Marie Curie of Sorbonne University in Paris, France, from 5–7 November 2025. premc.org/dnarepair202...

A great cell death meeting is happening in Bern, Switzerland on Sept. 4-5, 2025!

and registration is free!!!

meetings.ls2.ch/sa2m-2025

Cancer associated to low-penetrance TP53 variants: insights from p.R337H The TP53 p.R337H variant, prevalent in Southern Brazil, is linked to variable cancer risk for pediatric and adult cancers. Unlike high-penetrance TP53 pathogenic variants, many carriers remain cancer ...

www.cell.com/trends/cance...

Good Sunday!

www.nature.com/articles/s41...

Register now: application deadline for the 7th 🇩🇪German-🇫🇷French 🧬DNA Repair Meeting, taking place in Paris from November 5 to 7, 2025, is fast approaching.
To submit applications and for full event details, please go to the website:
👉 lnkd.in/dfJVjYFQ

p53 status determines the epigenetic response to demethylating agents Azacitidine and Decitabine 5’-Azacitidine (Aza) and 5-Aza-2’-deoxycytidine (Dac) are widely used demethylating drugs that directly integrate into nucleic acids. They are frequently used interchangeably, surprisingly as their se...

"p53 status determines the epigenetic response to demethylating agents Azacitidine and Decitabine"

Nice to see this work finalised on @biorxivpreprint.bsky.social

Congrats to Matthew van de Pette @mrc-tu.bsky.social and colleagues.

www.biorxiv.org/content/10.1...