Greg Jefferis

Wow congratulations @jkohl.bsky.social! Proud scientific parent :)

And here's the official announcement from our Janelia collaborators with a fantastic visualisation from @philiphubbard.bsky.social. See more at male-cns.janelia.org/media. Downloads are humming and we have solved the first data access queries. Happy exploring! #drosophila #connectomics #malecns.

Male CNS Connectome A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

We're very proud to be releasing the complete male fly CNS connectome!

It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators.

More soon...
www.janelia.org/project-team...

Comparison with previous female connectomes reveals sex differences across the adult brain at synaptic resolution for the first time. Full news story and preprint describing this massive team effort coming soon!

This dataset provides two major advances. It is the first fully proofread and annotated brain and nerve cord connectome with 166,696 proofread neurons annotated with 11,691 cell types. It is also the first connectome of a male brain.

Male CNS Connectome A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

Interested in the mechanisms of neurogenesis, and how they might converge/differ across species, regions, and life epochs? Check this out, wonderful location and great science! Please RT

neuro-unige.ch/news/csf-mee...

Congratulations. Sorry that I won’t have the chance to bump into you at Bob’s anymore but hope the move goes really well!

Those darned Europeans …

A Developmental Atlas of the Drosophila Nerve Cord Uncovers a Global Temporal Code for Neuronal Identity The assembly of functional neural circuits relies on the generation of diverse neural types with precise molecular identity and connectivity. Unlocking general principles of neuronal specification and...

After building a beautifully annotated single cell atlas, senior authors @sebastiancachero.bsky.social and @erikadona.bsky.social found a hidden birth order code. @biorxivpreprint.bsky.social here: www.biorxiv.org/content/10.1...
Read on for more ⬇️2/8

ALT text: A UMAP representation of a single cell RNAseq dataset from the Drosophila ventral nerve cord as well as images of the Drosophila nerve cord connectome and different stages of fly development.

Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns?
To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠
#preprint thread ⬇️1/8

a penguin is sticking his head out of a hole next to a job application ALT: a penguin is sticking his head out of a hole next to a job application

📢 We are hiring! 📢
For our @wellcometrust.bsky.social grant on information gathering biases in #OCD and #Schizophrenia, we are looking for a Postdoc in Computational Modelling, supervised by Peter Dayan and myself.
Interested? See all the details in the job advert here: devcompsy.org/wp-content/u...

It was a good experience to step back and briefly take stock of the amazing progress in connectomics since I started working on this stuff (20 years ago!)

thanks as well to @natrevneuro.nature.com for the constructive editorial interactions.

"The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades."

4000 labs is a severe understatement, likely off by an order of magnitude. Even non-fly people use and benefit from FlyBase. It is one of the cornerstones of the genome era.

With @megyounger.bsky.social's lab, et al., we present the first connectomics work in the disease-vector mosquito Aedes aegypti, revealing how its brain is wired to detect host cues.

Preprint: doi.org/10.1101/2025...

#Neuroscience #Connectomics #vEM #VectorBiology 🧪

We are looking for 2 postdocs to join my lab at Sussex University in Brighton, UK (South of London, on the sea). One position is for a molecular/cell biologist, the other, for a neurobiologist/behavioural person. Drosophila experience desirable. Flyer w/more info below. Please repost. Thank you!

Research Group Leader in Chemical/Synthetic Biology at MRC Laboratory of Molecular Biology Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).

Alan Turing Institute told to focus on defence or lose funding - Research Professional News Science secretary threatens to pull defence R&D funds, while reforms could see EPSRC grant revisited

Big story breaking this evening.

Alan Turing Institute told to focus on defence or lose funding.

The science secretary Peter Kyle has threatened to pull defence R&D funds, while reforms could see EPSRC grant revisited.

Free to read.

www.researchprofessionalnews.com/rr-news-uk-p...

Volume rendering of the ctenophore aboral organ reconstructed by volume EM, showing the gravisensory balancers and the four quadrants.

In our new preprint we describe the synaptic #connectome of the nerve net in the ctenophore gravisensory organ. https://www.biorxiv.org/content/10.1101/2025.06.26.661250v1 #biology #neuroscience #ctenophore #vEM

🎉We are delighted to announce that Professor Stephen Montgomery @ebablab.bsky.social‬ will be the 3rd Prince Philip Professor of Ecology and Evolution.

We look forward to welcoming him next year!

Thanks @markdhumphries.bsky.social looks very nice. Getting a 404 in that link. neuralcomputation.uk/registration... ?

Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...

🚨Anyone want a job?🚨
We have two #postdocs up for grabs! 🧪
- cell developmental biology/#evodevo/#neuroevodevo
- bioinformatics and molecular biology
Both working on brain evolution in Heliconiini butterflies
Details below! Please repost 🙏 1/n

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.

Professor Edward Bullmore FMedSci FRS | Royal Society Explore the history of the Royal Society, including our motto and discover our timeline of key events.

Professor Edward Bullmore FRS is elected a Fellow of the Royal Society. His work has focused on developing new tools for analysis of the complex network organization of the human brain, and understanding how schizophrenia & other major mental health disorders arise. royalsociety.org/people/ed-bu...

🚨This is a HUGE escalation and a deliberate effort to use the government against Trump's enemies. Weaponizing the Student and Exchange Visitor Program certification against Harvard to punish them for pushing back is a new low — and needlessly punishes thousands of innocent students.

Many thanks, John. I think especially recognises the collective impact of our group’s collaborative work.

📢 New paper alert!

Comparative connectomics of Drosophila descending and ascending neurons

A new publication in Nature from our Drosophila Connectomics group and Jefferis group @jefferis.bsky.social @mrclmb.bsky.social

www.nature.com/articles/s41...

@cambridgebiosci.bsky.social @nature.com