MichaelMcMurray lab

The CloneChecker kit from ThermoScientific is great: suspend an E. coli colony in Green Buffer, boil and add restriction digest buffer and enzyme, digest 30 min, run entire reaction on gel and there’s visible bands. Seems like we should be able to guess what’s in this proprietary buffer. Ideas?

Postdoctoral Researcher in Plant Evolutionary Genomics The postdoctoral researcher will work in Dr. Michael Grillo’s plant evolutionary genetics lab. The goal of this research project is to understand the genomic basis of plant-microbiome variation in leg...

I am hiring a postdoc to examine the genomic and evolutionary basis of plant microbiome variation in legumes. There are opportunities to gain teaching experience. Chicago is a great city to live in! Please help spread the word.
share.google/gukbzS1zdIx6...

The genomic basis of symbiotic integration at University of Bath on FindAPhD.com PhD Project - The genomic basis of symbiotic integration at University of Bath, listed on FindAPhD.com

There's a PhD position now available with me in Bath, on the evolution of symbiosis. www.findaphd.com/phds/project.... The supervisory team also includes @anja1.bsky.social @phil-donoghue.bsky.social and others. NB, this is open both to UK-based students *and* to international students :)

Now that I'm settled in at @umasschan.bsky.social, I'm hiring at all levels: grad students, post-docs, and software engineers/bioinformaticians!

The goal of my lab is to understand the regulatory role of every nucleotide in our genomes and how this changes across every cell in our bodies.

You assume the ice comes out of the machine RNase-free???

Something I’ve always wondered: why do so many (most?) researchers who use lab ice (i.e., in ice buckets to keep reagents cold) discard the ice in the sink rather than draining off any water and returning the ice to the ice machine? Do you think the ice is somehow “contaminated”, or something? 🧐

PubMed is in trouble

This is beyond bad for medical research

pubmed.ncbi.nlm.nih.gov

RFK Jr. poses a danger to the health and safety of all Americans. From cutting critical cancer research to spreading lies about Tylenol, it’s very clear RFK Jr. is not fit to serve.

That’s why I’m drafting articles of impeachment to remove him from office.

Leaflet-specific phospholipid imaging using genetically encoded proximity sensors - Nature Chemical Biology An approach combining bioorthogonal chemistry with genetically encoded fluorogen-activating proteins enables subcellular imaging of phospholipids and glycans, as well as the visualization of lipid tra...

Very excited to share new work out today in @natchembio.nature.com on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n) www.nature.com/articles/s41...

Asking BlueSky for help: For a review, I am trying to accurately credit the first paper that measured pairwise 3D distances between 2 pieces of DNA on the same chromosome (or cosmid). Is Trask 1989 the first?
I know of earlier single-locus papers (1982).
www.sciencedirect.com/science/arti...

Josh Morgan discusses how progress in cell biology is hindered by significance testing and the need for a shift to effect size estimation. rupress.org/jcb/article/...

📕 In #Reproducibility and Best Practices in Cell Biology: rupress.org/jcb/collecti...

Discovery of additional ancient genome duplications in yeasts Whole genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages[1][1],[2][2], preceding adaptive radiations in vertebrates[3][3]–[5][4], teleost fish[6][5],[7][6], and an...

Checkout our new preprint with the @rokaslab.bsky.social!:

www.biorxiv.org/content/10.1...

doi: doi.org/10.1101/2025...

On #ScienceUnderSeige BY @peterhotezmdphd.bsky.social @michaelemann.bsky.social @latimes.com @hiltzikm.bsky.social www.latimes.com/business/sto...

We present a simple method to easily increase the imageable depth of an expansion microscopy gel on a typical inverted microscope ten-fold, using some carefully placed FEP film and a water dipping objective lens:

This kind of discovery is so important and illuminating!! Congratulations to the authors

OK--fluorescent protein friends. We want an antibody to TagRFP that works in immunofluorescence. Any suggestions? Re-post please

Madhani Lab – Junior/Assistant Specialist University of California, San Francisco is hiring. Apply now!

We're hiring a tech for a project focused on the impact of genetic background on genetics and evolution. If you like doing lots of microbial evolution experiments and are good at bioinformatics/computation, this might be for you. aprecruit.ucsf.edu/JPF05782

a woman stands in front of a white board with the words you need to be careful written on it ALT: a woman stands in front of a white board with the words you need to be careful written on it

WARNING WARNING WARNING

#ResearchAdmini

I am hearing reports of NIH Awards being issued with ~15% indirect cost rate without comment. I believe the hope is that they will be accepted with noticing this.

Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited

Why strong mentorship was essential for my career success in science JoAnn Trejo has turned mentoring into an evidence-based science, driven by her own exposure to inspiring mentors.

Here you go..." Why strong mentorship was essential for my career success in science" JoAnn Trejo has turned mentoring into an evidence-based science, driven by her own exposure to inspiring mentors. www.nature.com/articles/d41...

If you are an "FFPE expert", could I ask you a few questions?

Let me know and I'll DM you 😊

Please RT

Having a 5 percentile R01 grant not being funded sucks so much. And having it falling through the cracks because of delays in council meetings and other administrative shenanigans even more.

Research Associate Screen reader users may encounter difficulty with this site. For assistance with applying, please contact hr-accessibleapplication@osu.edu. If you have questions while submitting an application, pleas...

I'm recruiting a lab manager for my soon-to-be-launched lab at Ohio State! If you know of any recent grads who may be interested both in helping to build the lab and in developing skills in the cognitive neuroscience of memory, please share!

osu.wd1.myworkdayjobs.com/en-US/OSUCar...

PO just confirmed that our 5th percentile R01 is not getting funded. Past NCI Payline at 4 percent. Cant believe it.

I was looking at published grant reviewer lists for a study section, and found myself listed as reviewer at a study section that I had not attended or been asked to attend.

Now I wonder how many rosters list me ,and how many PIs are mad at me for grant reviews at meetings I had nothing to do with…

Also upload full video as supplemental fig for Methods section of paper 😉

My first two Bhattacharya email day...

This one is coming in hot...

1/n

But unfortunately this isn’t all happy news. Due to the NSF budget request & associated mandated forward funding, my budget was cut by a whopping 41%.

TBH, that was a pretty devastating blow as a junior faculty at an under resourced university. It meant cutting opportunities for nearly 10 people.

Genome Sciences is looking for a Director of Departmental Computing. This is a rare opportunity for someone interested in leading our excellent IT team, building and maintaining computational infrastructure, and working closely with our faculty and labs uwhires.admin.washington.edu/ENG/candidat...