Zoran Paunic

meet me at #ESOTcongress in London 🇬🇧

🗓️ July 1, 13:00-14:00, ROOM s5

to discuss Torque Teno virus 🦠 based immunologic monotoring

viruses 🦠 can be superheroes 🦸

#ESOT2025 #TTVguide #ESOT

Loop Diuretics in Anuric Hemodialysis Patients for the Clearance of Protein-Bound Uremic Toxins AbstractBackground. In chronic kidney disease (CKD), the accumulation of protein-bound uremic toxins (PBUT), such as hippuric acid, p-cresyl sulfate, and i

An interesting pilot study: a regular dose of loop diuretic enhances hemodialysis clearance of protein-bound uremic toxins in anuric patients. academic.oup.com/ckj/advance-...

Furosemide and Serum Protein-Bound Uraemic Toxin Concentrations in Patients with Chronic Kidney Disease Furosemide is commonly prescribed to patients with CKD but may impair the kidney’s excretion of protein-bound uraemic toxins (PBUTs) via the organic anion transporters 1 and 3 (OAT1/OAT3). We evaluate...

In CKD, furosemide use—especially >100 mg/day—is linked to higher serum levels of protein-bound uraemic toxins like IS, PCS, Kyn, and IAA. Furosemide may impair toxin clearance via OAT1/3 transporters, contributing to toxin accumulation.
#podoctyetalk #CKD #Nephsky
www.kireports.org/article/S246...

Does Iodinated Contrast Affect Residual Renal Function in Dialysis Patients? A Systematic Review and Meta-Analysis - PubMed Intravascularly administered contrast media may not result in a significant reduction of residual function in dialysis patients.

We pooled all the (suboptimal data) together in this meta-analysis pubmed.ncbi.nlm.nih.gov/32155642/

Hardly any effect on residual function

Transmission of tuberculosis via #kidneyallograft

Renal allograft-transmitted #tuberculosis is a rare and potentially fatal infection in the early post-transplant period.

doi.org/10.1016/j.kint.2024.08.011

#KINephrologyImage #kidneytransplantation #MedSky #NephSky

A retrospective study from Taiwan: ESA vs w/o ESA in CKD and ESKD patients:
HR for incident malignancy 1.84 with ESA; for genitourinary malignancy 12.55.
The risk was positively correlated with the cumulative dose of ESA.

doi: 10.1111/cts.13353

Check out this special collection that highlights the clinical connection between disorders of the kidneys and the heart:

https://bit.ly/3AVbArF

#Cardiorenal