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Jose Jimenez

@jjimenez.bsky.social

Reader in Synthetic Biology at Imperial College London #synbio and evolution for health, the environment and the circular economy josejimenezlab.com

1,143 Followers  |  836 Following  |  127 Posts  |  Joined: 02.10.2023  |  1.6999

Latest posts by jjimenez.bsky.social on Bluesky

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‘It’s a question of humanity’: how a small Spanish town made headlines over its immigration stance Mayor explains why Villamalea unanimously backed call to regularise undocumented migrants – across party lines

This is how Castilla La Mancha will conquer the world: blending tradition and empathy. I'd recommend all world leaders to complete a couple of grape harvests (vendimia) to develop thoughtful leadership. Great mix of cardio and strength exercise too!
www.theguardian.com/world/2025/o...

11.10.2025 14:33 — 👍 2    🔁 0    💬 1    📌 0
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Pseudomonas putida JM37 as a novel bacterial chassis for ethylene glycol upcycling Ethylene glycol (EG), one of the main monomers of polyethylene terephthalate (PET), is an attractive target for microbial upcycling. Despite this interest, there is a limited number of described organ...

New preprint this time through a fantastic collaboration with @jorgebarriuso.bsky.social and team. We have discovered the genetic basis behind the remarkable ability of Pseudomonas putida JM37 to use the PET #plastic monomer ethylene glycol as a growth substrate! www.biorxiv.org/content/10.1...

08.10.2025 08:48 — 👍 4    🔁 1    💬 0    📌 0
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Metabolic interplay drives population cycles in a cross-feeding microbial community - Nature Communications Here the authors leverage a crossfeeding, engineered microbial community to demonstrate that strain abundance cycles are robust across environmental conditions. They pair this with a nonlinear dynamic model to elucidate population cycles.

Metabolic interplay drives population cycles in a cross-feeding microbial community

@natcomms.nature.com from @oventurelli2.bsky.social

www.nature.com/articles/s41...

07.10.2025 19:09 — 👍 35    🔁 17    💬 0    📌 1

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

03.10.2025 16:06 — 👍 46    🔁 84    💬 0    📌 2
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Mapping the evolution of computationally designed protein binders [new]
Evolve comp. mini-protein binders *in vivo*. Maps seq-affinity.

06.10.2025 03:15 — 👍 3    🔁 2    💬 0    📌 0
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PhD Scholarship project: Engineering biology approaches to mammalian cells at Imperial College London on FindAPhD.com PhD Project - PhD Scholarship project: Engineering biology approaches to mammalian cells at Imperial College London, listed on FindAPhD.com

PhD positions available in our group! Please share! www.findaphd.com/phds/project...

06.10.2025 07:31 — 👍 1    🔁 3    💬 0    📌 0
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Microbial stem cells support productivity in dedicated factory cells in an asymmetrically dividing E. coli system
doi.org/10.1101/2025...

06.10.2025 07:03 — 👍 7    🔁 3    💬 0    📌 0
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Directed evolution and characterisation of light harvesting complexes with altered energy transfer dynamics in purple non-sulfur bacteria Purple non-sulfur bacteria (PNSB) are metabolically versatile microorganisms that inhabit diverse environments taking advantage of a remarkably efficient photosynthetic machinery. In this work, we des...

Preprint alert!! Delighted to share Eve Nery's work exploring the evolutionary landscape of light-harvesting complexes. She found a new variant shifted to the red that allows purple bacteria to grow faster under high intensity light www.biorxiv.org/content/10.1...

03.10.2025 07:07 — 👍 4    🔁 0    💬 0    📌 0
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Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria - Nature Communications Engineered gene circuits often degrade over time due to mutation and selection. Here the authors use a host-aware modelling framework to develop genetic controllers to sustain synthetic gene expression. They identify a range of design trade-offs in production, robustness and long-term performance.

Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria
doi.org/10.1038/s414...

02.10.2025 07:12 — 👍 7    🔁 3    💬 0    📌 1
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Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

I am looking for a motivated #Postdoctoral #Researcher to join my group at Imperial @imperialcollegeldn.bsky.social @imperiallifesci.bsky.social. The project focuses on #Antimicrobial #Materials & #Biomimetic #Interfaces
Please repost!

@imperialsci.bsky.social
www.imperial.ac.uk/jobs/search-...

19.09.2025 10:09 — 👍 5    🔁 9    💬 1    📌 1

Let's go with Pseulomonas for now...

20.09.2025 14:44 — 👍 0    🔁 0    💬 0    📌 0

Nice to see some familiar faces!!!!😍

16.09.2025 13:35 — 👍 1    🔁 0    💬 0    📌 0
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The diversity of PET degrading enzymes: A systematic review of sequence, structure, and function Polyethylene terephthalate (PET) is one of the most significant plastic pollutants. Unlike other plastic polymers, PET can be degraded by PET-hydrolytic enzymes (PETases). Over the past two decades, ....

onlinelibrary.wiley.com/doi/full/10....

14.09.2025 06:59 — 👍 8    🔁 3    💬 0    📌 0

A bit of an awkward request but hoping that someone can help. We are desperately looking for a vial of CHO-S cells that we could use. Ideally in the London area. Thanks!

11.09.2025 15:20 — 👍 0    🔁 0    💬 0    📌 0

Ok, to be precise (thanks @marcsdionne.bsky.social), they are considering implementing triage

10.09.2025 11:47 — 👍 1    🔁 0    💬 0    📌 0

It would certainly help panel members, but for applicants would be key to know what their senior management will do if their proposals happen to end in the unfundable tier.

10.09.2025 11:28 — 👍 0    🔁 0    💬 0    📌 0

BBSRC to implement triage of proposals pre-panel and rolling deadlines to reduce assessment burden. Interesting times ahead!

10.09.2025 11:20 — 👍 0    🔁 0    💬 1    📌 1
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EvoChromo: Evolutionary approaches to research in chromatin Chromatin is the complex of DNA, RNA and protein that is found making up the chromosomes in eukaryotic cells. Chromatin is essential for proper genome function and is involved in chromosome segregati…

Please re-post:

Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo...

Abstract deadline: 30 September

08.09.2025 11:14 — 👍 79    🔁 62    💬 0    📌 4

Well, JeS is no longer in use (for better or worse) so maybe it's time to suggest this again?

07.09.2025 13:21 — 👍 3    🔁 0    💬 0    📌 0

Slightly diminish a band:
Joy Subtraction

13.08.2025 08:53 — 👍 2    🔁 0    💬 0    📌 0
116 FB 5 Research Assistant (m/f/d) field of Theoretical Ecology and Evolution or Computational Biology: Uni Osnabrück

I am excited to announce that the position of a senior postdoc (3 +3 years) in the field of theoretical biology is available in my group.

The position provides the opportunity to closely interact with experimentalists and develop own research projects.

Please RT.

Details 👇:
shorturl.at/iiiOv

08.08.2025 10:09 — 👍 96    🔁 119    💬 2    📌 4
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Excited to be at the MRC Laboratory of Molecular Biology (LMB) for the first time to present at the Life Sciences Students Symposium. Such impressive venue. No pressure!

11.07.2025 13:43 — 👍 3    🔁 1    💬 0    📌 0

Appealing to the wisdom of the crowd: Let's say molecule X produced by microbe Y is used as an 'organic' fertiliser. If molecule X is produced recombinantly in microbe Z, purified and used as a fertiliser, could this process receive 'organic certification'?

08.07.2025 11:33 — 👍 2    🔁 0    💬 0    📌 0
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The best part of my job is spending my days with this wonderful group of very talented people! @imperialcollegeldn.bsky.social @imperiallifesci.bsky.social

30.06.2025 21:19 — 👍 4    🔁 0    💬 0    📌 0
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We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-...

30.06.2025 14:34 — 👍 19    🔁 34    💬 1    📌 0
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#OliviaRodrigo just won a few die hard fans at home. #TheCure #Glastonbury

29.06.2025 21:39 — 👍 3    🔁 0    💬 0    📌 0
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An island of strang... wait!

27.06.2025 17:38 — 👍 0    🔁 0    💬 0    📌 0

Reposting this advert. Only a few days left to apply to this position. Come join us!!

26.06.2025 18:36 — 👍 3    🔁 2    💬 0    📌 0

Question for the Pseudomonas putida aficionados. Is there an application of P. putida different from PHA biosynthesis being used at an industrial scale? Maybe muconate production? If so, does it involve recombinant protein production from plasmids? @vdlorenzo.bsky.social @pabnik.bsky.social

19.06.2025 12:59 — 👍 2    🔁 0    💬 2    📌 0
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New research hubs to cut carbon and reshape UK manufacturing From green steel and recycled plastics to turning waste into new materials and using AI to boost productivity, four hubs will tackle UK manufacturing challenges.

Delighted to share good news after a long embargo! We'll be part of C-Loop an EPSRC Bio-manufacturing Hub focusing on making value out of waste!! Looking forward to this project led by Stephen Wallace at Edinburgh #circulareconomy @imperiallifesci.bsky.social www.ukri.org/news/new-res...

19.06.2025 08:13 — 👍 7    🔁 2    💬 0    📌 0

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