Endocrine Society Journals

Glycemic Derangements With Capivasertib—From Hyperglycemia to Diabetic Ketoacidosis: A Report of 3 Cases Abstract. Capiversatib is a pan-Ak strain transforming inhibitor used in combination with fulvestrant for the treatment of hormone receptor-positive advanc

Glycemic Derangements with #Capivasertib—From Hyperglycemia to #DiabeticKetoacidosis: A Report of Three Cases. Read more in #JCEMCaseReports: bit.ly/4n3isFA #InsulinResistance @endocrinesociety.bsky.social

A Critical Assessment of Fasting to Promote Metabolic Health and Longevity. Read more in #Endocrine Reviews: bit.ly/46WvDC1 #IntermittentFasting #WeightLoss #BoneMetabolism @endocrinesociety.bsky.social

Sex Differences in Ketogenic Diet Response Reveal Gonadal Hormone Interaction With FGF21 in Mice Abstract. Although indicated as adjunctive therapy for seizure disorders, ketogenic diets (KDs) have gained popularity for weight loss and mitigating the m

Sex Differences in #KetogenicDiet Response Reveal #GonadalHormone Interaction With #FGF21 in Mice. Read more in #JES: bit.ly/435lp14 @endocrinesociety.bsky.social

Changes in 90-Day Time in Range Among Youth With Type 1 Diabetes Initiating Different Automated Insulin Delivery Systems AbstractContext. Glycemic outcomes in youth with type 1 diabetes (T1D) in the United States using the 2 most common automated insulin delivery (AID) system

Changes in 90-Day Time in Range Among Youth With #Type1Diabetes Initiating Different #AutomatedInsulinDelivery Systems. Read more in #JCEM : bit.ly/4oceFqh #ContinuousGlucoseMonitor @endocrinesociety.bsky.social

Nongenomic Stimulatory Effect of T3 on Calcium Dynamics in GnRH Neurons via Integrin αVβ3 Abstract. Many clinical studies have identified correlations between thyroid dysfunction and reproductive issues, yet the underlying mechanisms behind this

Nongenomic Stimulatory Effect of T3 on Calcium Dynamics in GnRH Neurons via Integrin αVβ3. Read more in #Endocrinology: bit.ly/4q2loEW #GnRHNeurons #ThyroidHormones #ReproductiveAxis
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Clinical Pearls From JCEM Case Reports: ENDO 2025 On July 14, 2025, the journal hosted the third annual “Clinical Pearls from JCEM Case Reports” at the annual Endocrine Society meeting in San Francisco, Ca

Clinical Pearls From JCEM Case Reports: ENDO 2025. Read more in #JCEMCaseReports: bit.ly/4nw1fp9 #ENDO2025 @endocrinesociety.bsky.social

Exploring the Role of the Gut Microbiome Across the Lifespan: Implications for Aging and Metabolic Disorders Abstract. The gut microbiome is widely accepted to play a crucial role in human health and disease. These intestinal microbiota are not only involved in ga

Exploring the Role of the Gut Microbiome Across the Lifespan: Implications for Aging and Metabolic Disorders. Read more in #JES : bit.ly/489VcSx
#obesity #aging #MASLD @endocrinesociety.bsky.social

Prenatal Testosterone Exposure Is Linked to Sexually Dimorphic Changes in Body Composition in 7-Year-Old Children AbstractContext. Maternal free testosterone (FT) increases during the third trimester and FT is higher in pregnant women with polycystic ovary syndrome (PC

Prenatal #Testosterone Exposure Is Linked to Sexually Dimorphic Changes in Body Composition in 7-Year-Old Children. Read more in #JCEM : bit.ly/4nSicdT
#PCOS #gynoidfat @endocrinesociety.bsky.social

Pig Taste Cell-Derived Organoids Synthesize Insulin. Read more in #Endocrinology: bit.ly/48MKe5z #Gustatory #Insulin #TasteOrganoids @endocrinesociety.bsky.social

Liver Transplantation as a Metabolic Treatment in Glycogen Storage Disease Type Ia. Read more in #JCEMCaseReports: bit.ly/46TWakA #osteoporosis #livertransplantation #hepaticadenoma @endocrinesociety.bsky.social

Innovative Molecules and Delivery Technologies Enabling the Future of GLP-1-Based Therapies. Read more in #EndocrineReviews: bit.ly/428OSH2
#GLP-1 #GIP #diabetes #obesity @endocrinesociety.bsky.social

Epigenetic Changes Associated With Obesity-related Metabolic Comorbidities Abstract. Obesity arises from a complex interaction of genetic, hormonal, dietary, and behavioral factors that drive chronic energy imbalance, excessive fa

#Epigenetic Changes Associated With Obesity-related Metabolic Comorbidities. Read more in #JES : bit.ly/42cg9Zf #obesity #DNAmethylation
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Utility of the C-Peptide/Insulin Molar Ratio for Distinguishing Type A Insulin Resistance Syndrome From Type 2 Diabetes AbstractObjective. Type A insulin resistance syndrome (IRS), characterized by impaired insulin receptor function due to variants of the insulin receptor ge

Utility of the C-Peptide/Insulin Molar Ratio for Distinguishing Type A Insulin Resistance Syndrome From Type 2 Diabetes. Read more in #JCEM : bit.ly/42w8KnR
#C-peptidereactivity #hyperinsulinemia #immunoreactiveinsulin
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Role of PROP1 in Postnatal Pituitary Gland Maturation Abstract. Mutations in the pituitary-specific transcription factor PROP1 are the most common known cause of hypopituitarism in humans. Prop1 is the first p

Role of PROP1 in Postnatal Pituitary Gland Maturation. Read more in #Endocrinology : bit.ly/4nDzbAx
#SOX2 #stemcells #POU1F1-lineage @endocrinesociety.bsky.social

Recombinant Human GH in Managing Refractory Hypoglycemia in a Young Patient With Embryonal Rhabdomyosarcoma Abstract. Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome associated with various malignancies, mediated by the overproduction

Recombinant Human GH in Managing Refractory Hypoglycemia in a Young Patient with Embryonal Rhabdomyosarcoma. Read more in #JCEM Case Reports: bit.ly/42w8bdJ #IGF-2 #somatropin @endocrinesociety.bsky.social

Perspectives From Adolescents and Young Adults With Klinefelter Syndrome on Testosterone Supplementation and Fertility AbstractContext. Infertility and testicular dysfunction are typical features of Klinefelter syndrome (KS; 47,XXY). KS affects ∼1:600 male births, making it

Perspectives From Adolescents and Young Adults with #Klinefelter Syndrome on Testosterone Supplementation and Fertility. Read more in #JES: bit.ly/4pG4CeO #TESE #Infertility @endocrinesociety.bsky.social

Browse the latest Thematic Issue from @endocrinesociety.bsky.social Journals focusing on #Neuroendocrinology. This collection ranges from clinical reports of hypothalamic-pituitary disorders to basic science investigations. Read now: bit.ly/3IPhLl1 @oxfordacademic.bsky.social #EndoSky

Altered Expression of Aromatase and Estrogen Receptors in Adipose Tissue From Men With Obesity or Type 2 Diabetes AbstractContext. Obesity and insulin resistance in men are linked to decreased testosterone and increased estradiol (E2) levels. Aromatase (ARO) converts t

Altered expression of #aromatase and estrogen receptors in adipose tissue from men with obesity or type 2 diabetes. Read more in #JCEMCaseReports: bit.ly/4ngNISd #estradiol #obesity #T2D @endocrinesociety.bsky.social

Attending #ENDO2025? Explore the science behind the sessions with our new Thematic Issue—featuring articles by invited speakers & session chairs.🩺 Dive into expert insights from our journals: bit.ly/4kk0kFR

Fatal, Fulminant, Necrotizing Pancreatitis Associated With Recent Tirzepatide Initiation Abstract. As obesity is increasing in prevalence and its associated morbidity and mortality are escalating worldwide, medications like tirzepatide are freq

Fatal, fulminant, necrotizing #pancreatitis associated with recent #tirzepatide initiation
doi.org/10.1210/jcem.... Featured in #JCEMCaseReports #OpenAccess
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Growth Hormone Replacement in Craniopharyngioma: Analysis of the Hypopituitary Control and Complications Study (HypoCCS) AbstractContext. Patients with adult-onset craniopharyngioma (CP) show metabolic dysfunction and panhypopituitarism. Growth hormone (GH) deficiency is ofte

#GrowthHormone replacement in #craniopharyngioma: analysis of the hypopituitary control and complications study (HypoCCS). #OpenAccess. Featured study in #JES. #pituitary
doi.org/10.1210/jend...
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Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes Abstract. PTH-related disorders have a major impact on bone metabolism and skeletal properties because of the pivotal role of PTH in calcium and phosphate

#Bone in #parathyroid diseases revisited: evidence from epidemiological, surgical and new drug outcomes. Featured review in #EndocrineReviews. #OpenAccess #epidemiology #surgery
@endocrinesociety.bsky.social
doi.org/10.1210/endr...

Predictors of Fracture in Middle-Aged and Older Adults With Type 2 Diabetes and Overweight or Obesity AbstractContext. Persons with type 2 diabetes have increased fracture risk that existing fracture risk assessment tools underestimate.Objective. Identify f

Predictors of #fracture in middle-aged and older adults with type 2 #diabetes and overweight or #obesity. Featured study in #JCEM. #FreeToView #bone
doi.org/10.1210/clin...
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Mechanisms of Flame Retardant Toxicity and Their Impacts on Anxiety and Cognition in the Brain Abstract. Flame retardants have been used extensively to reduce flammability in household and industrial materials raising significant concerns due to thei

Mechanisms of flame retardant toxicity and their impacts on #anxiety and #cognition in the brain. doi.org/10.1210/endo... Featured review in #Endocrinology. #FreeToView #EDCs
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Functional Suppression of a Prolactinoma by a Dopamine-Secreting Paraganglioma Abstract. Prolactin-secreting pituitary adenomas are typically treated with dopamine agonists to inhibit prolactin secretion and reduce tumor size. Dopamin

Functional suppression of a #prolactinoma by a dopamine-secreting #paraganglioma. Featured in #JCEMCaseReports. #OpenAccess #dopamine
academic.oup.com/jcemcr/artic...
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Effect of Time-Restricted Eating on β-Cell Function in Adults With Type 2 Diabetes AbstractContext. Time-restricted eating (TRE), which consists of restricting the eating window to typically 4 to 8 hours (while fasting for the remaining h

Effect of time-restricted eating on β-cell function in adults with type 2 #diabetes. Featured study in #JCEM #FreeToView #BetaCell #T2D academic.oup.com/jcem/article...
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The Glucagon Receptor Is Expressed in the Frontal Cortex and Impaired Signaling Associates With Cognitive Decline Abstract. Individuals with type 2 diabetes (T2D) have an elevated risk of cognitive decline, yet the mechanisms connecting these pathologies remain unclear

The glucagon receptor is expressed in the frontal cortex and impaired signaling associates with cognitive decline #OpenAccess Featured study in #JES #cognition #GlucagonReceptor #neuroendocrinology academic.oup.com/jes/article/...
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Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes Abstract. PTH-related disorders have a major impact on bone metabolism and skeletal properties because of the pivotal role of PTH in calcium and phosphate

Bone in #parathyroid diseases revisited: evidence from epidemiological, surgical and new drug outcomes. Featured in #EndocrineReviews. #OpenAccess #bone academic.oup.com/edrv/advance...
@endocrinesociety.bsky.social

Functional Analysis of HSD17B3-Deficient Male Mice Reveals Roles for HSD17B7 and HSD17B12 in Testosterone Biosynthesis Abstract. Historically, 17β-hydroxysteroid dehydrogenase type 3 (HSD17B3) was thought to be the key enzyme responsible for testicular testosterone producti

Functional analysis of HSD17B3-deficient male mice reveals roles for HSD17B7 and HSD17B12 in #testosterone biosynthesis
#OpenAccess Featured study in #Endocrinology
doi.org/10.1210/endo...
@endocrinesociety.bsky.social

Transient Blindness in Metformin-associated Lactic Acidosis: Resolution With Supportive Care Abstract. Metformin remains the first-line pharmacologic treatment for type 2 diabetes mellitus due to its well-established efficacy and safety profile. Ho

Transient #Blindness in #Metformin -associated Lactic #Acidosis: Resolution With Supportive Care. Featured in #JCEMCaseReports #T2D
doi.org/10.1210/jcem...
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