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Karim Gharbi

@drkarimgharbi.bsky.social

Genomics veteran • Data-minded biologist • Head of Technical Genomics at Earlham Institute (Norwich, England) • he/him

106 Followers  |  149 Following  |  2 Posts  |  Joined: 07.01.2024  |  1.8197

Latest posts by drkarimgharbi.bsky.social on Bluesky

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Developing the next generation of technical specialists with T-Levels The Earlham Institute T-Level industry placement programme inspires the next generation of young people pursuing careers in science.

Two of our students - Rosie and Archie - shared their experience working with our Technical Genomics and Earlham Biofoundry Groups, developing their skills and gaining practical training in #genomics and #laboratory #automation. 🧬

🔗 buff.ly/KF08OL9

@drkarimgharbi.bsky.social @cgrandel.bsky.social

09.07.2025 12:02 — 👍 1    🔁 4    💬 0    📌 0
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T Level industry placements in higher education and research Sector insights and practical guidance

We're proud to support T Level Students at the Earlham Institute and a new report from @uk-itss.bsky.social today showcases the impact of industry placements for supporting young people to thrive in a range of scientific careers. 🥼

🔗 buff.ly/7JMmK1V?

@tech-commit.bsky.social

09.07.2025 12:02 — 👍 3    🔁 1    💬 1    📌 1
Attendees chatting in the Earlham Institute Atrium besides a display of scientific posters.

Attendees chatting in the Earlham Institute Atrium besides a display of scientific posters.

Attendees sitting in the conference room listening to one of the speakers who is not visible in the photo.

Attendees sitting in the conference room listening to one of the speakers who is not visible in the photo.

Manuela D'Agata, Head of Sales Development and Marketing at Tecan, stands in front of the presentation screen to introduce the day.

Manuela D'Agata, Head of Sales Development and Marketing at Tecan, stands in front of the presentation screen to introduce the day.

Senior Scientist Thomas Brabbs introduces his talk on overcoming hurdles of PacBio HiFi automation.

Senior Scientist Thomas Brabbs introduces his talk on overcoming hurdles of PacBio HiFi automation.

A great day with #Tecan bringing together those involved in lab #automation for #genomics to discuss the latest trends, considerations, and applications of this technology.

26.06.2025 15:00 — 👍 1    🔁 1    💬 0    📌 0

Join us in Norwich for a day of automation goodness, including talks, lab tours, and more.

14.05.2025 08:16 — 👍 1    🔁 1    💬 0    📌 0

Really nice work led by @conradn.bsky.social , and a prime example of how transformative technology can reveal new biology.

12.05.2025 12:25 — 👍 1    🔁 1    💬 0    📌 0
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Haerty Group - Comparative Genomics and Population Genetics Investigating the evolution of functional noncoding sequences

Great to see Group Leader Dr Wilfried Haerty (@whaerty.bsky.social) presenting his work at #PacBioPRISM this afternoon!

Dr Haerty leads our #CellularGenomics research programme and is interested in the impact of variation on gene and transcript expression across scale.

@pacbio.bsky.social

29.04.2025 13:18 — 👍 1    🔁 1    💬 0    📌 0
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NBRI Transformative Genomics - Annual User Meeting A one-day meeting of the bioscience community to hear the latest updates and applications from the BBSRC-funded National Bioscience Research Infrastructure in Transformative Genomics at the Earlham…

TALK: We're looking forward to hearing from @katielong.bsky.social next month, presenting research from her collaboration with our #singlecell team using #spatialtranscriptomics on expression in developing wheat spikelets.

Register to join: https://buff.ly/3QAK2w4

@johninnescentre.bsky.social

27.02.2025 08:05 — 👍 3    🔁 2    💬 1    📌 0
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NBRI Transformative Genomics - Annual User Meeting A one-day meeting of the bioscience community to hear the latest updates and applications from the BBSRC-funded National Bioscience Research Infrastructure in Transformative Genomics at the Earlham…

TALK: Interested in #genomics for #bioscience? Caoimhe Morley from @ucl.ac.uk will be joining us next month at our User Group meeting, to share her research on targeted #longread sequencing for somatic structural variant discovery in Multiple System Atrophy brains.

Register to join 👇

28.02.2025 10:00 — 👍 0    🔁 1    💬 0    📌 0
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NBRI Transformative Genomics - Annual User Meeting A one-day meeting of the bioscience community to hear the latest updates and applications from the BBSRC-funded National Bioscience Research Infrastructure in Transformative Genomics at the Earlham…

🔬 Discover how #SpatialTranscriptomics is unlocking insights into the ageing brain with @parker-aim.bsky.social (@quadraminstitute.bsky.social) at the NBRI Transformative Genomics User Meeting.

📅 Register:

01.03.2025 14:01 — 👍 1    🔁 2    💬 0    📌 0

🦠 Multidrug resistance in human fungal pathogens is a growing threat. Join Mat Fisher (@imperialcollegeldn.bsky.social) at the NBRI Transformative Genomics User Meeting as he explores the drivers behind this challenge.

📅 Registration closes tomorrow: buff.ly/3EUgAyx

#Genomics #Sequencing

02.03.2025 13:00 — 👍 2    🔁 1    💬 0    📌 0
Graphic promoting the speakers at the NBRI Transformative Genomics User Group Meeting: Drivers of emerging multidrug resistance in human fungal pathogens by Mat Fisher, Imperial College London. Spatial transcriptomics reveals expression gradients in developing wheat inflorescences at cellular resolution, by Katie Long, John Innes Centre. Targeted long-read sequencing for somatic structural variant discovery in Multiple System Atrophy brains, by Caoimhe Morley, University College London. Ultra-long read sequencing resolves the pattern of replication site initiation across the human genome, byConrad Nieduszynski, Earlham Institute. Spatial transcriptomics and the ageing brain, by Aimée Parker, Quadram Institute.

Graphic promoting the speakers at the NBRI Transformative Genomics User Group Meeting: Drivers of emerging multidrug resistance in human fungal pathogens by Mat Fisher, Imperial College London. Spatial transcriptomics reveals expression gradients in developing wheat inflorescences at cellular resolution, by Katie Long, John Innes Centre. Targeted long-read sequencing for somatic structural variant discovery in Multiple System Atrophy brains, by Caoimhe Morley, University College London. Ultra-long read sequencing resolves the pattern of replication site initiation across the human genome, byConrad Nieduszynski, Earlham Institute. Spatial transcriptomics and the ageing brain, by Aimée Parker, Quadram Institute.

Make sure you join our NBRI Transformative Genomics User Meeting to hear @conradn.bsky.social discuss how ultra-long read sequencing reveals patterns of replication site initiation across the human genome.

Join us here 👉 https://buff.ly/4blYAJl

#genomics #sequencing @drkarimgharbi.bsky.social

27.02.2025 16:00 — 👍 2    🔁 3    💬 0    📌 0
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LITE2: Reduced bias and increased throughput The Earlham Institute's improved Low Input, Transposase Enabled (LITE) protocol is a low-cost method for high-throughput whole genome sequencing with reduced DNA input.

💬 “By using a much-expanded set of robust barcodes, we can pool more samples in the sequencing lane, making better use of our capacity and further lowering the cost per sample.” - @drkarimgharbi.bsky.social

LITE2 takes affordable genome sequencing to a new level

12.02.2025 13:06 — 👍 3    🔁 2    💬 0    📌 0
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LITE2 takes affordable genome sequencing to a new level The Earlham Institute's improved Low Input, Transposase Enabled (LITE) protocol is a low-cost method for high-throughput whole genome sequencing with reduced DNA input.

Technological advances have transformed #sequencing, but costs and timescales can still be limiting, especially in library generation.

Earlham Institute's updated Low Input, Transposase Enabled (LITE) protocol offers low-cost, high-throughput whole #genome sequencing with reduced DNA input. 💻🧬🧪

05.02.2025 11:00 — 👍 6    🔁 5    💬 0    📌 1
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Nuclear and mitochondrial genome assemblies for the endangered wood-decaying fungus Somion occarium Abstract. Somion occarium is a wood-decaying bracket fungus belonging to an order known to be rich in useful chemical compounds. Despite its widespread dis

A team from the Earlham Institute and the Czech Academy of Sciences have #sequenced and assembled the first near-complete annotated #genome of the wood-decaying bracket fungus, Somion occarium, as part of @ergabiodiv.bsky.social. 🧪

🖥️ 🧬

@rowenahill.bsky.social @drkarimgharbi.bsky.social

20.01.2025 08:35 — 👍 7    🔁 3    💬 1    📌 1
Image promoting the Earlham Institute's participation at the Festival of Genomics and Biodata 2025, including details of two talks:

Iain Macaulay, Group Leader, participating in a panel discussion on 'Overcoming data challenges of high-resolution biology' on Thursday 30 January, from 16:05 to 17:05.

Karim Gharbi, Head of Technical Genomics, and Conrad Nieduszynski, Group Leader, will present a talk titled 'Ultra-long read sequencing resolves the pattern of DNA replication initiation across the human genome' on Thursday 30 January, from 16:35 to 17:05.

Image promoting the Earlham Institute's participation at the Festival of Genomics and Biodata 2025, including details of two talks: Iain Macaulay, Group Leader, participating in a panel discussion on 'Overcoming data challenges of high-resolution biology' on Thursday 30 January, from 16:05 to 17:05. Karim Gharbi, Head of Technical Genomics, and Conrad Nieduszynski, Group Leader, will present a talk titled 'Ultra-long read sequencing resolves the pattern of DNA replication initiation across the human genome' on Thursday 30 January, from 16:35 to 17:05.

Catch our scientists at the #FestivalofGenomics later this month where they'll be discussing overcoming data challenges in #singlecell biology, and ultra #longread #sequencing in #DNAreplication.👇🧬🖥️

@flgenomics.bsky.social @drkarimgharbi.bsky.social @conradn.bsky.social @whatchamacaulay.bsky.social

16.01.2025 11:14 — 👍 7    🔁 3    💬 1    📌 0
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New sequenced genome sheds light on weed resistance Genomic advances reveal how similar weeds can dominate wheat fields that are geographically separated by over 5,000 miles.

A new study in Scientific Data from the Earlham Institute, @rothamsted.bsky.social, @rbgkew.bsky.social, and @ergabiodiv.bsky.social presents a high-quality annotated orange foxtail grass #genome, shedding light on what makes it such an exceptional survivor in modern #crop systems.

🧬🖥️🌿

09.01.2025 08:55 — 👍 14    🔁 5    💬 1    📌 0
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New Data Centre at Norwich Research Park set to bolster UK’s bioscience capability A new state-of-the-art Data Centre at Norwich Research Park has been given the green light for construction.

💬 “This development will deliver the computational performance we need to support our science into the future." - @neilhall.bsky.social, Director.

New #DataCentre at #NorwichResearchPark set to bolster UK’s #bioscience capability.

@quadraminstitute.bsky.social @thesainsburylab.bsky.social

09.12.2024 09:15 — 👍 8    🔁 4    💬 0    📌 0
Professor Dame Janet Thornton introducing Professor Elinor Karlsson.

Professor Dame Janet Thornton introducing Professor Elinor Karlsson.

Professor Neil Hall introducing today's lecture.

Professor Neil Hall introducing today's lecture.

Professor Elinor Karlsson discussing her work on the Zoomomia project, with a large projection screen behind her displaying a cover of Science magazine.

Professor Elinor Karlsson discussing her work on the Zoomomia project, with a large projection screen behind her displaying a cover of Science magazine.

Huge thanks to @elinork.bsky.social for her brilliant talk about #comparative #genomics and the #Zoomomia project at today's inaugural Dame Janet Thornton Lecture. We were pleased to be joined by Prof Thornton to introduce the lecture.

@neilhall.bsky.social @broadinstitute.org

25.11.2024 15:21 — 👍 14    🔁 6    💬 0    📌 0
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New grasspea genome unlocks rapid climate-smart breeding New grasspea genome has been published online, providing researchers with a new tool to unlocks potential for rapid climate-smart breeding

Great to see this important resource published.

The reference #genome was supported by @pacbio.bsky.social HiFi data generated through the Transformative Genomics National Bioscience Research Infrastructure at the Earlham Institute, led by @drkarimgharbi.bsky.social.

nisd.ac.uk/new-grasspea...

25.10.2024 07:44 — 👍 1    🔁 1    💬 0    📌 0

@drkarimgharbi is following 20 prominent accounts