Francesco Padovani

Francesco Padovani

@padovaf.bsky.social

Research Scientist in Cell and Computational Biology at Helmholtz Munich | Creator of Cell-ACDC and SpotMAX | Excited about mitochondrial DNA and AI-driven bioimage analysis | Dad of 2

59 Followers 96 Following 5 Posts Joined Nov 2024
2 months ago
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πŸ“―πŸ‘¨β€πŸš€ Calling all #bioimage analysis aficionados. #EZInput is out! We wanted to bring #ImageJ’s capacity to record settings to the #Python ecosystem 🐍. It is a declarative library for generating UIs that just work. Done with @guijacquemet.bsky.social lab

arxiv.org/abs/2601.08859 #ScientificComputing

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2 months ago
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Deep Learning for Microscopy Image Analysis Topics The following will be covered extensively during lectures, exercises, and project work: Image denoising and restoration (fully supervised and self-supervised) Image translation (e.g.,

🚨 Alarm!!! 🚨
AI/ML course for microscopy image analysis!!! 🧐
In 2026 at Janelia (@hhmijanelia.bsky.social), no tuition, housing and meals provided! Isn’t that borderline unbelievable?!?

20 students, ~14 TAs and lecturers
πŸ—“οΈ June 4-18 2026

✍️ Jan 15 2026 ✍️

πŸ” pls!!

www.janelia.org/you-janelia/...

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2 months ago
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As we wrap up the year, we’re reflecting on what AI4Life delivered and what continues beyond the project.
AI4Life concluded in August 2025, but its outcomes remain central to FAIR, accessible AI-powered bioimage analysis.
Here’s where to start:
www.eurobioimaging.eu/news/ai4life...

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3 months ago
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#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question πŸ™ƒ, because the #preprint. Software is available in every #Fiji near you.

www.biorxiv.org/content/10.6...

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3 months ago

The new version of TrackMate, the v8.1 has just been released. It builds upon the recent v8, linked below, and offers two main improvements πŸ‘‡

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3 months ago

Trackastra is part of the brand-new TrackMate v8.

It is the first deep-learning-based ("AI") drop-in replacement for TrackMate's regular LAP-Track algorithm.

Tracks out of the box for many types of datasets (bacteria, fluorescent nuclei, phase contrast cell culture etc), zero parameters to tune πŸ€–

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3 months ago

MASSIVE thank you to everyone involved in this year's I2K meeting - 32 SUPER sessions from our volunteer presenters, and so many super-engaged participants.

HUGE shoutout to Aditi from @bioimagingna.bsky.social for being the organizational wizard!

See you in the recordings and at next year's!

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4 months ago
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Single-cell susceptibility to viral infection is driven by variable cell states Not all cells that can be infected by a virus become infected with that virus. Single-cell clone tracing reveals intrinsic cell states with variable expression patterns that increase susceptibility to...

So awesome to have this great paper from Sam Reffsin and Sara Cherry out! In it, we use retrospective clone tracing to show that there are particular single cell states that are more susceptible to viral infection (both SARS-CoV-2 and flu)!

www.cell.com/cell/fulltex...

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4 months ago
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I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...

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4 months ago
A fluorescent embryo on black text, with the words 
Halfway to I2K: Virtual Tutorials on Image Analysis
November 17-19, 2025
Virtual Conference for beginners to developers
i2kconference.org
Image Credit - "Sweet Embryo",Travis D. Carney, BINA Image Contest 2024

Just 4 days until the start of I2K and its 33 totally free image analysis tutorials and events! Please share with your "home networks", especially early career researchers - the videos will be amazing and high-impact no matter how many people attend live, BUT (1/x)

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4 months ago

Applications close tomorrow - hope to see you in January! If not, stay tuned for future editions :)

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4 months ago
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Alternate proteins from the same gene contribute differently to health and rare disease | Whitehead Institute Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients thro...

From an accidental discovery of hidden biology to a new framework to understanding and diagnosing rare disease. Thrilled to share the most recent work from our lab and the amazing Jimmy Ly.

wi.mit.edu/news/alterna...

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4 months ago
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Seeing our good old AURA-Net from 2021 (doi.org/10.1109/ISBI...) end up 2nd on a 2025 U-Net variants leaderboard was not on my bingo card for this year, but here we are
(source: doi.org/10.48550/arX...)

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4 months ago

Do you want to learn more about 25+ bioimage analysis tools, 100% for free? Sign up to attend Halfway to I2K today! tinyurl.com/Halfway-to-I...
Wishing you'd submitted a tool or workshop but missed the deadline? GREAT NEWS, we just extended one week! Submit by Friday - airtable.com/app2zpB8d82r...

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4 months ago

Registration for Halfway to I2K is now OPEN! And workshop submission is still too (for a bit)! Join 20+ presenters and counting, and hundreds of attendees in learning about image analysis, whether you're a complete beginner or a total pro.

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5 months ago
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πŸ”¬For 22 years, we have been organizing #Mifobio "Functional Microscopy for Biology" the @cnrs.fr thematic school.

πŸŽ“ Courses, Seminars, Round Tables, Workshops. The overall theme concerns #biological_imaging in its most interdisciplinary aspects.

πŸ‘‰ Program: imabio-cnrs.fr

#GDRImaBio #Mifobio2025

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5 months ago
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See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧡...

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5 months ago

Automatic filament tracing in 3D data is now only a few clicks (or one macro) away! In the amazing #BigTrace FIJI plugin by @ekatrukha.bsky.social 🀩

My workflow will be to autotrace and then manually correct the autotraces, reducing the time for our tracing significantly!

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5 months ago

Halfway to I2K is BACK, friends of all kinds! Last year, 650 people attended 30+ TOTALLY FREE image analysis workshops of all kinds, across many timezones.

If you make image analysis software and want to teach it, workshop submissions are open now! We'd love to have your tool highlighted.

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5 months ago

That sounds fantastic, cannot wait to try them out, congratulations!

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5 months ago
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πŸš€ Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

πŸ”— www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

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5 months ago

It’s crucial that the bioimage community joins spaces long dominated by computer vision/CS to highlight challenges in microscopy data and how we tackle them. Brilliant talk from @aafkegros.bsky.social showing how biology is both exciting and challengingπŸ‘©πŸ»β€πŸ’»πŸ”¬πŸ§¬πŸ¦  #bioimage #microscopy #interdisciplinary

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5 months ago
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Microscopy Nodes: handling large biological volumes β€” Blender Conference 2025 YouTube video by Blender

I gave a talk at Blender Conference yesterday, showing how biological volumes work, and how to visualize them in Blender πŸ˜‹ youtu.be/WPajSWX730o?... #bcon25

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7 months ago
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No second chance for a first post - so I made it count:

Finished my PhD on glucose signaling in yeast's G2 phase.
Thanks to the whole Ewald lab and our fantastic collaborators!

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1 year ago

πŸ”¬πŸŽ€ As pre-announced a few days ago... please let us proudly present to you: π‘΄π’Šπ’„π’“π’π•Šπ’‘π’π’Šπ’• - your ticket to imaging more, imaging more gentle, and/or imaging more efficient. πŸ”¬

doi.org/10.1101/2025...

Like ❀️, repost πŸ”‚, and most importantly... please send feedback βœ‰οΈ our way! πŸ™

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9 months ago
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Out today in @natmethods.nature.com : Spotiflow, our transcript localization method for imaging-based spatial transcriptomics. Led by amazing PhD student @albertdm.bsky.social, joint work w @gioelelamanno.bsky.social at EPFL / @scadsai.bsky.social
www.nature.com/articles/s41...
rdcu.be/epIB7

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9 months ago
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Spotiflow: accurate and efficient spot detection for fluorescence microscopy with deep stereographic flow regression Nature Methods - Spotiflow uses deep learning for subpixel-accurate spot detection in diverse 2D and 3D images. The improved accuracy offered by Spotiflow enables improved biological insights in...

Spotiflow, our deep learning based spot detection method for microscopy, is now published in @natmethods.nature.com!
Since the pre-print, we have added many features, notably native 3D detection!
@maweigert.bsky.social @gioelelamanno.bsky.social @epfl-brainmind.bsky.social
Paper: rdcu.be/epIB7
(1/N)

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10 months ago
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Wow, just implemented the new Cellpose-SAM from @computingnature.bsky.social in NimbusImage and it's *awesome*! Give it a try!
nimbusimage.com

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10 months ago

⏳ Only 8 days left to register for the AI4Life Community Event in Helsinki!

Day 1️⃣: Workshops for life scientists, software devs, AI researchers & image analysts
Day 2️⃣: Talks, discussions & networking

If that sounds like you, don’t miss it!
πŸ‘‰ ai4life.eurobioimaging.eu/event/ai4lif...

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11 months ago
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During the workshop earlier this week we discussed how important it is to inspect histograms of image regions in some projects. Thus, here comes stackview.histogram() - new in stackview 0.15.0 πŸ₯³
github.com/haesleinhuep...

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