Nicolas Vabret

Nicolas Vabret

@neoviral.bsky.social

Assistant Professor @SinaiImmuno @MountSinaiNYC #Immunology #Cancer #Virology www.vabretlab.com

655 Followers 881 Following 27 Posts Joined Nov 2024
3 days ago
Preview
The Unmaking of the American University For decades, research universities have relied on federal funding, with no guarantee that it will last. Now their survival may depend on compliance with the government.

The Trump Administration is waging war on universities by suspending their funds. N.I.H. grants to universities are down by more than 90 per cent in the current fiscal year; so far in 2026, the National Cancer Institute hasn’t made a single grant. newyorkermag.visitlink.me/oxA7Ey

54 36 7 3
3 days ago
Video thumbnail

At Immunoschool, Eicke Latz will discuss targeting inflammasomes, the innate immune sensors linking lifestyle exposures - from Western diet to metabolic stress - to the chronic inflammation that impacts healthspan.

Hear more at the online Immunoschool Mar 23 - 25: www.eventbrite.com/e/internatio...

5 2 0 0
3 weeks ago
Video thumbnail

3 days. Global faculty and learners of all career stages. Aging, immunity and translation at the cutting edge.

Save your spot: www.eventbrite.com/e/internatio...

Explore the program: immunoschool.org

The second speaker will be Vishwa Deep Dixit of the Yale Univertsity Center for Research on Aging

4 4 0 0
3 weeks ago
Video thumbnail

FREE registration is now open for this year’s International Immunoschool on IMMUNE AGING:
✍️ www.eventbrite.com/e/internatio...

From mechanism to translation, there’s something for every career stage. Explore the program here:
🧐 immunoschool.org

First speaker is @miriammerad.bsky.social...

3 3 1 1
2 months ago

Exactly. Goal is tumor control, right?

0 0 1 0
2 months ago

Let them dominate

1 0 1 0
2 months ago

Easy 2

0 0 1 0
3 months ago
Preview
Sign the Petition Support a New York State Biomedical Institute for a Healthier, More Affordable Future

📢 SIGN & SHARE THE PETITION! 📢

New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW

37 39 1 10
4 months ago

When you have paylines that are that low (e.g. NCI R01: 4%), does it still make sense to discuss half of the applications?
It means < 10% of *discussed* applications will be actually funded.
Not that I am happy with any of this.

1 0 0 0
4 months ago

Check out our highlight of an exciting new preprint by Dr. Claudia Rivera from Dr. Yasmine Belkaid's group 👇

0 1 0 0
4 months ago
Retroelements orchestrate gut tolerance - Nature Reviews Immunology A preprint by Rivera et al. explores how retroelement expression establishes a tolerogenic environment towards food antigens in the gut, shedding new insights into the immune regulatory role of retroe...

www.nature.com/articles/s41...

0 0 0 1
4 months ago

Interesting study from the ppl @solvingforsci.bsky.social. Very much in line with our earlier findings with @preprintclub.bsky.social (www.biorxiv.org/content/10.1...) :
1/ Reviewers can distinguish quality and impact (+novelty in our model)
2/ Trainees want to review
3/ Authors love the experience

2 1 0 0
4 months ago

Very exciting to finally see clinical data where viral mimicry provides survival benefits

2 2 0 0
4 months ago
Preview
Local activation of mutant RIG-I by short noncoding Y-RNA in the kidney triggers lethal nephritis Y-RNA activates RIG-I gain-of-function mutants in the kidney, causing lethal autoimmune diseases including lupus nephritis.

Short, noncoding YRNA can activate pathological variants of the innate sensor RIG-I, causing autoinflammation and #lupus nephritis in mouse models.

Learn more in #ScienceImmunology: https://scim.ag/43ewTiV

18 6 0 0
4 months ago

It was a great experience to present our latest work on cancer vaccines in front of an audience of TE experts

3 1 0 0
4 months ago
Post image Post image

Proud of our Yu-Chan Chih for receiving the Trainee Innovation Idea Award for his work on cancer vaccination 👏🥇

4 1 0 0
4 months ago

Y RNAs getting some of the recognition they deserve

0 0 0 0
5 months ago

This is a fast moving field and new mechanisms are uncovered (almost) every week.

0 0 1 0
5 months ago

Check out our latest in @cp-trendscancer.bsky.social where rockstar PhD student @laurarosenberg.bsky.social reviews cancer therapies known to induce innate immune responses through the reactivation of Transposable Elements.

18 6 1 0
5 months ago

Check out our review on the role of #retroelements and #viralmimicry during cancer treatment! @neoviral.bsky.social

3 1 0 0
6 months ago
Preview
Trump Is Shutting Down the War On Cancer

America’s cancer research system is under threat in one of its most productive moments. www.nytimes.com/2025/09/14/m...

0 1 0 0
6 months ago

The Empire State can’t afford to fall behind. A group of scientists is launching NY-CURES to fight for state and city level investment in research.✊
📢 Sign up & show Albany we stand UNITED for science.
👉 www.nycures.org @miriammerad.bsky.social @bogunoviclab.bsky.social
#AdvocateForScience #NYCURES

11 6 0 0
6 months ago
Post image

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀

Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities.

Sign up. Stay informed. Join the movement: www.nycures.org/

47 55 4 6
6 months ago
Preview
Generation of Lipid Nanoparticle mRNA Vaccines and Evaluation of Antigen-Specific CD8+ T-Cell Responses mRNA vaccines have revolutionized vaccine development against infectious diseases, as demonstrated by the rapid creation and deployment of vaccines for SARS-CoV-2. In this chapter, we present a protoc...

Latest from us: we detail the protocol we use to generate mRNA-LNPs and to study immune response in preclinical setting.
link.springer.com/protocol/10....

1 1 0 0
9 months ago
Preview
Trump team pauses new student visa interviews as it weighs expanding social media vetting It’s the latest salvo against universities, many of whom rely heavily on foreign students for funds.
0 0 0 0
10 months ago
Preview
Locus specific human endogenous retroviruses reveal lymphoma subtypes The heterogeneity of cancers is driven by diverse mechanisms underlying oncogenesis such as differential ‘cell-of-origin’ progenitors, mutagenesis, and viral infections. Classification of B-cell lymph...

Read about her work on HERV expression in B-cell lymphomas here 👇
www.cell.com/iscience/ful...

1 1 0 0
10 months ago
Post image

🎉 Congrats to student extraordinaire @bhavyasighs.bsky.social who earned a scholarship from #CIHR AND got a paper accepted in the same week!

3 1 1 1
10 months ago
Preview
Viral piracy of host RNA phosphatase DUSP11 by avipoxviruses Author summary Viruses face a critical challenge of disabling or avoiding host immune defenses. Cells typically recognize the presence of a virus through specific molecular markers, including triphosp...

Another nice example of a host-acquired gene in poxviruses, which modulates the host immune response.
dx.plos.org/10.1371/jour...

9 6 0 0
11 months ago
Preview
Exogenous RNA surveillance by proton-sensing TRIM25 Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens...

www.science.org/doi/10.1126/...

1 1 0 0
11 months ago

More great content from @preprintclub.bsky.social @epelmanlab.bsky.social. This @biorxiv-immuno.bsky.social preprint from Liu et al. reports that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure.

11 4 0 0