Nicolas Vabret

This is a fast moving field and new mechanisms are uncovered (almost) every week.

Check out our latest in @cp-trendscancer.bsky.social where rockstar PhD student @laurarosenberg.bsky.social reviews cancer therapies known to induce innate immune responses through the reactivation of Transposable Elements.

Check out our review on the role of #retroelements and #viralmimicry during cancer treatment! @neoviral.bsky.social

Trump Is Shutting Down the War On Cancer

America’s cancer research system is under threat in one of its most productive moments. www.nytimes.com/2025/09/14/m...

The Empire State can’t afford to fall behind. A group of scientists is launching NY-CURES to fight for state and city level investment in research.✊
📢 Sign up & show Albany we stand UNITED for science.
👉 www.nycures.org @miriammerad.bsky.social @bogunoviclab.bsky.social
#AdvocateForScience #NYCURES

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀

Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities.

Sign up. Stay informed. Join the movement: www.nycures.org/

Generation of Lipid Nanoparticle mRNA Vaccines and Evaluation of Antigen-Specific CD8+ T-Cell Responses mRNA vaccines have revolutionized vaccine development against infectious diseases, as demonstrated by the rapid creation and deployment of vaccines for SARS-CoV-2. In this chapter, we present a protoc...

Latest from us: we detail the protocol we use to generate mRNA-LNPs and to study immune response in preclinical setting.
link.springer.com/protocol/10....

Locus specific human endogenous retroviruses reveal lymphoma subtypes The heterogeneity of cancers is driven by diverse mechanisms underlying oncogenesis such as differential ‘cell-of-origin’ progenitors, mutagenesis, and viral infections. Classification of B-cell lymph...

Read about her work on HERV expression in B-cell lymphomas here 👇
www.cell.com/iscience/ful...

🎉 Congrats to student extraordinaire @bhavyasighs.bsky.social who earned a scholarship from #CIHR AND got a paper accepted in the same week!

Viral piracy of host RNA phosphatase DUSP11 by avipoxviruses Author summary Viruses face a critical challenge of disabling or avoiding host immune defenses. Cells typically recognize the presence of a virus through specific molecular markers, including triphosp...

Another nice example of a host-acquired gene in poxviruses, which modulates the host immune response.
dx.plos.org/10.1371/jour...

Exogenous RNA surveillance by proton-sensing TRIM25 Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens...

www.science.org/doi/10.1126/...

More great content from @preprintclub.bsky.social @epelmanlab.bsky.social. This @biorxiv-immuno.bsky.social preprint from Liu et al. reports that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure.

Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...

Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants kffhealthnews.org/news/article...

NIH to ax grants on vaccine hesitancy, mRNA vaccines Move reflects vaccine skepticism of health secretary Robert F. Kennedy Jr.

NIH to ax grants on vaccine hesitancy, mRNA vaccines www.science.org/content/arti...

Who funds biomedical research? @nature.com
www.nature.com/articles/d41...

Absolutely stellar presentations by Brian Brown, Rafi Ahmed, Michel Sadelain and Craig Crews happening now for day 1 of our immunoschool.

NYC #standupforscience

Join us tomorrow, March 7th, at Washington Square Park!
US Science is under unprecedented attack. Science saves lives, drives innovation and progress. Stand Up for Science, Stand Up for America. #standupforscience2025

🚨 Last days to register to next week #Immunoschool!
Don't miss out! 👇
t.co/nsPLcdX3wT

At next week's 🎓 Immunoschool 🎓, Dan Littman discovered how the microbiota shapes immune responses & the role of Th17 cells in autoimmunity. Register to hear about microbiota-immune interactions that influence immunotherapy, driving novel therapeutic strategies >>> www.eventbrite.com/e/internatio...

Don't forget to sign up for International ImmunoSchool, a FREE online course held on March 10–12! Learn from leaders in immunotherapy about the latest advancements in the field.

🔗 Register now: www.immunoschool.org

Nature Story "Revealed: NIH research grants still frozen despite lawsuits challenging Trump order"

(with non-paywalled link)

archive.ph/7h6Im

The link you shared says it’s cancelled. Do you have other info indicating it’s moving ahead?

Registration is now open for the next ImmunoSchool!

This year’s theme: "10 Years of Discovery in Immunotherapy." We’ve put together a stellar lineup of speakers—don’t miss it!

Free registration @ bit.ly/3WFj0Hc

#ImmunoSchool #Immunotherapy #CancerResearch

Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen
www.nature.com/articles/s41...
@lukasbunse.bsky.social @naturecomms.bsky.social

Very proud of my Ph.D student Ashley who brilliantly defended her thesis last Friday!

Call for entries 📣 The international €350K #EinsteinFoundationAward honors researchers and institutions across all scientific disciplines working to advance #research quality. Deadline: 30 April 2025 - please share! 🌍 (1/2)
➡️ award.einsteinfoundation.de
#OpenScience #reproducibility

We wanted to remind you that you can read our preprint feedback under the “Community reviews” button on @biorxivpreprint.bsky.social 😊