John Blenkinsopp

Scientists Discover How To “Switch Off” Cancer Genes for Good A new study shows that targeting key epigenetic proteins may permanently switch off cancer genes. Scientists at Monash University, working with Harvard University, report they have found a way to perm...

Oh, my goodness, this is a huge breakthrough in cancer research. This is another example of why it is crucially important to fund basic scientific research.
Scientists Discover How To “Switch Off” Cancer Genes for Good share.google/WFhMJP5m3AK4...

Single vaccine could protect against all coughs, colds and flus, researchers say A Stanford University team have tested their nasal spray vaccine in animals but still need to do human clinical trials.

BBC News - Single vaccine could protect against all coughs, colds and flus, researchers say
www.bbc.co.uk/news/article...

We studied the BMJ systematic review last week as part of the Journals Club and came to the same conclusion. Once we had removed the obviously biased papers and the obvious confounders, it was erm....obvious

Paracetamol is safe in pregnancy, says new evidence against Trump autism claims Researchers say their gold-standard review should put an end to the debate over use of the common painkiller during pregnancy.

BBC News - Paracetamol is safe in pregnancy, says new evidence against Trump autism claims - BBC News
www.bbc.co.uk/news/article...

Fame reduces musician life expectancy by four years, study finds Being a famous singer can lower your life as much as occasionally smoking cigarettes.

BBC News - Fame lowers life expectancy for musicians, study finds
www.bbc.com/news/article...

Cambridge 'swimming cap' brings hope for brain-injured babies Researchers are trialling a new technique to monitor brain function in newborns.

BBC News - Cambridge 'swimming cap' brings hope for brain-injured babies - BBC News
www.bbc.co.uk/news/article...

How the simmering freedom of speech row reached boiling point How did we reach a point where the UK is being compared to a 'tin pot Third World dictatorship'?

BBC News - How the simmering freedom of speech row reached boiling point - BBC News
www.bbc.co.uk/news/article...

Trump will reportedly link Tylenol to autism - but many experts are sceptical Some studies have suggested an association between the two, but experts say there is no causal relationship.

Oh blimey! I'll add the paper to next months Journals Club. Politicians saying the experts are wrong is always an interesting discussion - brace yourselves! BBC News - Trump will reportedly link pain reliever Tylenol to autism - but many experts are sceptical
www.bbc.com/news/article....

The Art Gallery is great and they have a nice cafe. They had a brilliant exhibition of prison artists when we were there. Ticket gets you into the museum as well.

Looking forward to running the national critical appraisal course tomorrow. An interesting RCT and a lot of number crunching.

Immunotherapy drug doubles cancer survival in breakthrough trial An international study found immunotherapy before surgery could give patients extra years of life.

BBC News - Breakthrough cancer drug doubles survival in trial
www.bbc.com/news/article...

Thank you, it was a pleasure.

Enjoyable day in London with @rigsbyhatstand.bsky.social visiting the Wallace Collection to see the Grayson Perry exhibition and then on to Balham for an interesting evening of thought provoking writing

Thank you to Michael, Mel and @malwinagudowska.bsky.social for a thought provoking and at times emotional discussion last night in London. Dank u wel! and Dziękuję.

New pill can slow progression of incurable breast cancer Around 3,000 women a year with advanced cancer could benefit from capivasertib which can slow the disease.

BBC News - New pill can slow progression of incurable breast cancer
www.bbc.com/news/article...

Your dignity honors the bravery of the Ukrainian people.

Be strong, be brave, be fearless.
You are never alone, dear President Zelenskyy.

We will continue working with you for a just and lasting peace.

Ethical Considerations in Conducting Research: Key Insights for Critical Appraisal In this tutorial, we explore the ethical considerations in conducting research and their impact on critical appraisal initiatives. Learn how to evaluate evid...

Explore the essentials of ethical research! Dive into key insights for critical appraisal here: 👉 buff.ly/4biyAyR

#EthicalConsiderations #ResearchEthics #CriticalAppraisal #ResponsibleResearch #HealthcareEthics

A thread about coin flips and what they can tell us about changing minds...

Imagine you’re holding a coin you believe is biased, so heads comes up about a quarter of the time - though you’re not sure. It could be bit higher or lower. Your belief about heads follows this probability distribution: 1/

Sounds like a plan

Very impressive and moving tribute.

Thanks, glad you enjoyed it!

Just finished the first of two critical appraisal sessions for groups in the Wye Valley this week. Lovely lot who worked really hard on predictive values and confidence intervals. So good to have such a motivated group working together!

Something to upset the Librarians here. The Anaesthetics library - shelved according to colour???

Last minute preparations for our 6th annual Critical Appraisal Day for the editors of the BNF at the Royal Society of Pharmaceuticals in London on Wednesday. Hopefully this fellow will still be waiting for me in reception at their museum.

Looking forward to a full house for today's national Critical Appraisal Day! We've got representatives from all over the country learning about RCT, Meta Analysis, Diagnostic data and how we can use statistics in health care. Then off to our Christmas party. ☺️

#RiverTees #Photography #Waterfall #LowForce #HighForce #Tees - High & Low Force waterfalls, river Tees 85 miles long starts in North Pennines & reaches the North Sea at industrial Teesside.

In our eighth special report on the Lucy Letby case, published online today, MD points out the danger of publishing a book about a killer nurse before her appeals’ process is completed is that you may end up being sued if she wins!

➡️ www.private-eye.co.uk/special-repo...

Painted wall of the anti-fascist Golden Smog pub in Stockton-on-Tees, NE England, painted in Spanish Republican colours and the three-point star of the International Brigades. I'd love a pint in the @thegoldensmog.bsky.social this afternoon.