Thank you to everyone who supported, discussed, and encouraged this work!
10.09.2025 15:21 — 👍 1 🔁 0 💬 0 📌 0
In our study, we show that critical point drying (CPD), a resin-free sample prep method, enhances contrast in X-ray phase-contrast imaging of brain tissue, with largely preserving ultrastructure.
✅ Compatible with femtosecond laser & plasma-FIB milling
✅ Effective for stained and unstained tissue
10.09.2025 15:20 — 👍 1 🔁 0 💬 1 📌 0
Critical point drying of brain tissue for X-ray phase contrast imaging
X-ray phase contrast tomography is emerging as a powerful method for imaging large volumes of brain tissue at sub-cellular resolution. However, current sample preparation methods are largely inherited...
Our pre-print is out!
Critical point drying of brain tissue for x-ray phase contrast imaging.
@apeart.bsky.social @yuxinzhang.bsky.social @jkbrmn.bsky.social @apacureanu.bsky.social @andreas-t-schaefer.bsky.social
@carlesbosch.bsky.social
@esrf.fr
@crick.ac.uk
bioarXiv: doi.org/10.1101/2025...
10.09.2025 15:19 — 👍 9 🔁 6 💬 1 📌 1
Computational Neuroscience & AI @ The Francis Crick Institute
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PhD at the Francis Crick Institute. Mouse olfaction; systems neuroscience; connectomics; correlative 2P, X-ray and EM.
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Aquí, tuitejo el què em passa pel cap molt de tant en tant.
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