Brady Johnston

Slide thanking the protein databank and all the researchers who contributed structures.

At #bps2026 : I loved the special acknowledgement of the @rcsbpdb.bsky.social and the MANY researchers who generated the experimental macromolecular structures that made it possible to build AI models for structure prediction.

You can create images like this in a couple minutes using 100% free software. Check out tutorials by @bradyajohnston.bsky.social

PyMol + Blender is cool. Learned this from @bradyajohnston.bsky.social

💪 NEW VIDEO:
Flying over the A-band of an atomic-scale model of a vertebrate muscle sarcomere. Let's explore the molecular mechanics that make your muscles work.

Rendered using @bradyajohnston.bsky.social 's molecular nodes

Model based on the incredible work of the @raunser-lab.bsky.social lab

Weekend well spent learning Blender and Molecular Nodes by the great @bradyajohnston.bsky.social

My first animation: "Interpretation of NRC2 resistosome assembly on the plasma membrane"

Happy to share our new preprint today! And it looks so nice that I couldn't help myself and made a little video 📺

Great teamwork as always Prof. @medbioinorgchem.bsky.social Prof. Gagliardi, Dr. Wragg and Julia Stebani!

Check it out here: chemrxiv.org/engage/chemr...

Hope you like it a lot!

Visualisation of the structure of PhotoSystem II supercomplex from an algae that is accustomed to low-light conditions (Chlamydomonas reihardtii). It has six yellow antennae complexes which gather light for photosynthesis.

Day 15 of making proteins for #ArtAdventCalendar

The PhotoSystem II supercomplex in plants contains light-gathering antenna complexes (yellow). More antennas means better photosynthesis in low-light conditions (like the version shown with SIX antennas).

More projects: e-nox.net/portfolio/

#SciArt

Visualisation of the structure of the Arc protein, shown as an icosahedral capsid (protein structure depicted as a ribbon), with a point light at its centre, throwing out shadow rays into the surrounding space.

Day 2 of #ArtAdventCalendar

Today's new protein is Arc, a protein found in the brain, which can form icosahedral capsids (like viruses) containing its Arc mRNA cargo. They are linked to regulation of synaptic plasticity and forming long-term memories.

More projects: e-nox.net/portfolio/

#SciArt

How do trypanosomes evolve resistance to sleeping sickness drugs?

Mutations in TbAQP2 🔵 can block melarsoprol and pentamidine 🟠 from entering the cell.

It was a pleasure to create this animation for Simone Weyand.
Read more here: elifesciences.org/reviewed-pre...
#blender #b3d #animation #science

Yes I’m definitely going to play around with something like this. Are you doing elastic network simulations on the alpha carbons?

I _really love_ the resulting aesthetics on this. I've played around with motion blur on structures before but this approach of many more frames & using alpha is a much nicer final look

Proteins are dynamic structures, but structural biology often shows them as static snapshots. Inspired by long-exposure photography and generative art, I built ProteinCHAOS, an artistic tool inspired by molecular dynamics to capture protein flexibility over time, much like long-exposure images.

GitHub - BradyAJohnston/MolecularNodes: Toolbox for molecular animations in Blender, powered by Geometry Nodes. Toolbox for molecular animations in Blender, powered by Geometry Nodes. - BradyAJohnston/MolecularNodes

A few years ago I was tinkering around in Blender, trying to figure out better ways to import molecular data for nicer visuals. I eventually and came up with an add-on that I released 100% free and open source: github.com/BradyAJohnst...

Strange for that to have a life of its own

If there is big biotech announcement happening, #MolecularNodes is being used for it. I only had the realisation in the past day, but it's strange to have my software very quickly become the visual face for $100M announcements and massive scientific breakthroughs.

Some animations I recently created for profluent.bio. As a structural biologist, I’m genuinely fascinated by their work in generative protein design. Congratulations to the team on their new round of funding!
#molecularnodes

Your go-to tutorial for simulating mesoscale membranes is here. Look no further for:
-Understanding the state of the field
-A guide for creating new models for your science
-Hands-on tutorials to simulate your very own membranes
See tinyurl.com/punk3tcu and the below 🧵 start your journey 💻

A blobby structure cut open showing its contents which are hélices and loops and light emitting spheres in the middle. This all depicts VPS45 protein

A conglomerate of lipid molecules forming a wall and separating two spaces with different contents

A space-like scene showing a sphere or vesicle about to be hooked by a multi subunit protein complex

Bringing invisible ideas to life.

#sciart #blender3D #illustration

*illustrations created for Mary Munson’s Lab website at UMass Chan Medical School*

ProteinDJ logo

I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5)
doi.org/10.1101/2025.09.24.678028 #proteindesign

Protein structures colored teal and purple floating above a reflective surface on a dark background. The protein structures spell out the word "SALAD" in all-capital letters.

Also, shoutout to @blender.org and @bradyajohnston.bsky.social for making it so easy to turn protein structures into nice images!
5/5

YouTube video by Blender Blending brains: Tales from the neuro department — Blender Conference 2025

so proud to share @jhuapl.bsky.social neuroscience research at #blenderconference2025 @blender.org ❤️

also shoutout to #microscopynodes by @aafkegros.bsky.social, here's to awesome new collabs born at blendercon!!!

Hello! I'm Behnoush, structural biology scientist from the Broad Institute. I also like to combine proteins structures and other scientific topics with art. Here are some journal cover arts I've created recently. Hope to find old and new friends here.
#Blender #b3d #MolecularNodes #GeometryNodes

YouTube video by Clockwork The Incredible Biology Powering Caffeine

New video about caffeine linked here:
youtu.be/fNR-GY-WoAI

Rendered in #blender3d using @bradyajohnston.bsky.social 's brilliant Molecular Nodes extension.

Make sure you check out the incredible coffee from @thegooddotstore.bsky.social 's Keats & Co by visiting keats.watchclockwork.com

What's the opposite of Artificial Intelligence? Naturally Occurring Stupidity?

Whatever it is, that's what I'm here for!

Check out my new film here - made with love, by humans, for humans: youtu.be/iNMxVBnIrwQ

#animation #shortfilm #blender #b3d

Please wait a few seconds and try again

Most complex golden gate wins

RosettaFold 3 is here! 🧬🚀

AtomWorks (the foundational data pipeline powering it) is perhaps the really most exciting part of this release!

Congratulations @simonmathis.bsky.social and team!!! ❤️

bioRxiv preprint: www.biorxiv.org/content/10.1...

Never meet your heroes

Thrilled to share my first corresponding author paper as a project leader in @hillerlab.bsky.social ‪ Amazing work from first author @annaleder.bsky.social We discovered multi-chaperone condensates in the ER that revolutionise the current vision of protein folding!
www.nature.com/articles/s41...

Will it ever live up to the memories though??

🕒 NEW VIDEO 🕒

How can a cell know the time? Let's explore the beautiful 24-hour cycle produced by #KaiC proteins in the cyanobacteria S. Elongatus. Rendered in #blender3d with @bradyajohnston.bsky.social's brilliant Molecular Nodes add-on. #biology