Thrilled to see our story now out at @naturecomms.bsky.social
A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social
Such a tiny RNA with such a wide range of functions
www.nature.com/articles/s41...

👋 I'm glad to advertise this new preprint led by the group of Olga Soutourina @i2bcparissaclay.bsky.social including @johann-i2bc.bsky.social - work in collaboration with the Canadian lab of Louis-Charles Fortier and other I2BC members including myself 😊
Check it out ⤵️

Last @i2bcparissaclay.bsky.social PhD day! I’m happy to discover the work of the future generation of researchers!

RQC2 is a major player in peptide release from stalled ribosomes - PubMed Eukaryotic cells prevent the accumulation of potentially toxic aberrant polypeptides and maintain ribosome availability through surveillance and clearance mechanisms, including the evolutionarily cons...

A new publication from my lab a great work done with fantastic colleagues from #IGDR (Reynald Gillet’s team for all the cryoem work. pubmed.ncbi.nlm.nih.gov/40187343/

Congratulations to all the candidates who qualified for the #CNRS #CRCN competition in #Section21. Such brilliant science and incredible enthusiasm! Keep it up!

c3n-cn.fr/2025/01/31/c...

DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria | PNAS Natural transformation (NT) represents one of the major modes of horizontal gene transfer in bacterial species. During NT, cells can take up free D...

📣 Happy to announce that "DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria" just got published in PNAS www.pnas.org/doi/abs/10.1...
🧬🧶👩‍🔬👩‍💻 Collaborative and interdisciplinary work, together with the groups of Ankur Dalia and J. Pablo Radicella

A bifunctional snoRNA with separable activities in guiding rRNA 2’-O-methylation and scaffolding gametogenesis effectors - Nature Communications Small nucleolar RNAs (snoRNAs) are known for their role in RNA modification to regulate gene expression. Here, the authors identify a snoRNA that not only guides ribosomal RNA 2’- O-methylation but al...

Happy to see this collaborative study out! A multitasking snoRNA at play in ribosome biogenesis and gametogenesis in fission yeast - project led by Mathieu Rougemaille @i2bcparissaclay.bsky.social and supported by a joint funding from @agencerecherche.bsky.social 🙏 - www.nature.com/articles/s41...

Rendez-vous le 20 mai lors du Paris-Saclay Spring à l’École Polytechnique pour échanger sur les recherches et analyses effectuées à l'I2BC dans le domaine de la santé paris-saclay-spring.com

Rendez-vous le 20 mai lors du Paris-Saclay Spring à l’École Polytechnique pour échanger sur les recherches et analyses effectuées à l'I2BC pour la transition énergétique. paris-saclay-spring.com

Rendez-vous le 20 mai lors du Paris-Saclay Spring à l’École Polytechnique pour échanger sur les recherches et analyses effectuées à l'I2BC dans le domaine de l'environnement et de l'agriculture. paris-saclay-spring.com

Rejoignez-nous le 20 mai lors du Paris-Saclay Spring à l’École Polytechnique pour échanger sur le travail réalisé par les équipes de recherche et les plateformes technologiques de l'I2BC. paris-saclay-spring.com

Ces recherches ont notamment impliqué des scientifiques de l'Institut de biologie intégrative de la cellule (@i2bcparissaclay.bsky.social - @cea.fr / @cnrs.fr / @univparissaclay.bsky.social / @inrae-france.bsky.social / @inserm.fr), situé à Gif-sur-Yvette (Essonne).
@cnrsbiologie.bsky.social

Cytometry training CFE 2025. TP "Complementarity Sorting/Imaging"
@imagerie-gif.bsky.social @i2bcparissaclay.bsky.social @cnrs.fr

AlphaReps fold - AlphaReps bind - AlphaReps rock - at Advances in #Bioinspiration - Agathe Urvoas from
@i2bcparissaclay.bsky.social - on Artificial recognition proteins as tools for the design of bio inspired modular assemblies
@cnrs.fr - @inserm.fr - @cea.fr
#BMSV

Light, color, flowers, and fruits as an inspiration - @Manuel Jose Llansola-Portoles from @i2bcparissaclay.bsky.social at Advances in #Bioinspiration, talking about Flower Petals and Tomatoes as Inspiration for Advances Photocatalysts.
@cnrs.fr - @inserm.fr - @cea.fr
#BMSV

This work has been done at #I2BC @cnrsbiologie.bsky.social @cnrs-paris-saclay.bsky.social @i2bcparissaclay.bsky.social

Origines du Covid : retour aux sources Les origines du COVID-19 demeurent un mystère pour la communauté scientifique. Pourtant, comprendre son émergence pourrait nous aider à prévenir de futures pandémies. Comment l’analyse critique des ép...

www.radiofrance.fr/francecultur...

VIH-1 : le génome du virus produit plus d’antigènes qu’on ne le pensait Dans une étude publiée dans la revue Nature Communications, des scientifiques révèlent l’existence de nouveaux antigènes produits à partir du génome

#RésultatScientifique🔎 VIH : de nouvelles cibles pour l’immunité

@onamy.bsky.social et ses collaborateurs révèlent que des antigènes du génome du VIH activent une forte réponse immunitaire, ouvrant de nouvelles pistes pour les vaccins ! 🧬

Dual DNA replication modes: varying fork speeds and initiation rates within the spatial replication program in Xenopus Abstract. Large vertebrate genomes duplicate by activating tens of thousands of DNA replication origins, irregularly spaced along the genome. The spatial a

☯️ A Yin-Yang of chromosomes duplication!

Olivier Hyrien and collaborators at @i2bcparissaclay.bsky.social and @ijmonod.bsky.social reveal novel DNA replication strategies in a study published in @narjournal.bsky.social

Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling - Nature Communications Here, using ribosomal profiling, the authors characterize the translatome of HIV-1 revealing tens of alternative open reading frames (ARF) that encode conserved viral antigens and show that…

🤝 @cnrs-paris-saclay.bsky.social @cea.fr @univparissaclay.bsky.social @i2bcparissaclay.bsky.social

👉 Lire l'article dans @naturecomms.bsky.social
buff.ly/auTaifQ

Les frontières au sein de nos chromosomes façonnent les domaines fonctionnels adjacents Les chromosomes des mammifères, y compris ceux des humains, sont organisés en plusieurs milliers de « domaines fonctionnels » qui sont séparés par des f

#RésultatScientifique🔎 Les frontières de l’ADN, bien plus qu’une barrière !

@daannoordermeerlab.bsky.social et ses collaborateurs révèlent que les frontières chromosomiques ne font pas que séparer les gènes, elles modulent aussi leur organisation et leur activité. 🧬

buff.ly/JFEihtS

Save the date : Seminar Yves Gaudin - 1st of April - 11am @i2bcparissaclay.bsky.social @nadinelaguette.bsky.social

👋 @cnrs-paris-saclay.bsky.social @cnrs-paris.bsky.social @inserm.fr @univparissaclay.bsky.social @cea.fr @ibensens.bsky.social @i2bcparissaclay.bsky.social

👉 Lire l'article dans @pnas.org
buff.ly/QnRpRoh

Last day for our "Image Analysis course on FIJI"🔬🧪💻. Well done to all the trainees for hanging in there right to the end 💪. And thank you for all the discussion and good mood😃.
✏️Next session will be 12-14 Nov 25 still @i2bcparissaclay.bsky.social (Gif sur Yvette)

Celebrating the International Day of Women and Girls in Science at @i2bcparissaclay.bsky.social! Inspiring speeches from I2BC’s female scientists, plus a special visit from Sylvie Retailleau, who shared a wonderful reflection. Thank you a lot to the organizers! #WomenInScience

Comprendre les interactions protéine-ARN pour ouvrir la voie à de nouvelles approches thérapeutiques

#VendrediLecture 📚

Aujourd'hui, plongez dans l'univers fascinant des interactions protéine-ARN !

Découvrez comment ces mécanismes essentiels ouvrent la voie à des avancées thérapeutiques prometteuses 🧬💡

🤝 @i2bcparissaclay.bsky.social @jessicaandreani.bsky.social
➡️ À lire sur Focus Sciences

Don’t miss the online journal of @i2bcparissaclay.bsky.social 📰. We publish the latest scientific news from all I2BC departments, including updates from #GenomeBiologyI2BC 🧬.
Take a look now!

I2BC Paris-Saclay | Scoop.it Scoop.it enables professionals and businesses to research and publish content through its content curation tool.

Dear I2BC colleagues, if you want to have a look at the I2BC Scoop-it page, please follow this link: www.scoop.it/u/institut-d...

Regulation of DNA Topology in Archaea: State of the Art and Perspectives DNA topoisomerases are ubiquitous enzymes that play a crucial role in regulating DNA supercoiling which affects fundamental biological processes involving DNA. In this review, we summarize the curren....

I am happy to share that the review my former PhD student Paul Villain and I wrote was published: doi.org/10.1111/mmi....
#Archaea
#I2BC

6 more weeks to apply !

Become our new colleague at the Cell Biology Dpt and join the growing group of junior teams of @i2bcparissaclay.bsky.social shaping the scientific environment of the institute.

Apply if you are looking for a place to start a lab or forward to any potential candidates.