Full paper now out in GENETICS:
The relationship between sexual dimorphism and intersex correlation: do models support intuition?
π academic.oup.com/genetics/art...
#Evolution #QuantGenetics @GeneticsGSA
@hibernogruppe.bsky.social
Asst. Prof. JGU Mainz π©πͺ (he/him)| π𧬠wild bee evolution | ππ» salmonid genomics | https://github.com/joscolgan
Full paper now out in GENETICS:
The relationship between sexual dimorphism and intersex correlation: do models support intuition?
π academic.oup.com/genetics/art...
#Evolution #QuantGenetics @GeneticsGSA
1/ a single job opening receives >1000 applications. (I am not kidding).
How to stand out?
Most bioinformatics CVs look the same: Python, R, RNA-seq, pipelines.
But hiring managers donβt care about skills on paper.
They care about proof. π§΅
FANTASIA's paper is finally out! Check it out if you're interested in alternative methods to homology for functional annotation in nonmodel organisms π¦ππͺ±π§¬ππͺ²
@gemmaeling.bsky.social @amrojasm.bsky.social @ibe-barcelona.bsky.social @cabd-upo-csic.bsky.social
@csic.es www.nature.com/articles/s42...
π§¬π₯οΈ Thrilled that our paper "Tree-based differential testing using inferential uncertainty for RNA-seq" genome.cshlp.org/content/earl..., led by @noorpratap.bsky.social, & in collab with @mikelove.bsky.social, @fennecpaaaw.bsky.social and Jason Fan is now accepted at @genomeresearch.bsky.social. 1/4
21.08.2025 19:24 β π 39 π 9 π¬ 2 π 1Excited to share a new update to Mumemto, scaling MUM and conserved element finding to any size pangenome! Preprint out now w/ @benlangmead.bsky.social.
Mumemto scales to the new HPRC v2 release and beyond, and can merge in future assemblies without any recomputation! 1/n
Massive thanks to @tegangaetano.bsky.social and @fmanfredini.bsky.social for impecably hosting while I was over - fantastic to hear about all the exciting research going on in Aberdeenπ΄σ §σ ’σ ³σ £σ ΄σ Ώ, meeting great peopleπ», as well as seeing the wildlifeπ¦π¦π¦
23.05.2025 15:22 β π 2 π 0 π¬ 0 π 0Annotation of 200 insect genomes. Work driven by @stepbystepsolution.bsky.social and Mario Stanke within @gevol.bsky.social : www.biorxiv.org/content/10.1...
21.04.2025 05:37 β π 39 π 26 π¬ 1 π 1Simplify and elevate your data visualization with GGally, an R package designed to extend ggplot2.
Visualization: https://ggobi.github.io/ggally/
Details: https://statisticsglobe.com/online-course-data-visualization-ggplot2-r
#tidyverse #datavisualization #datasciencecourse #data #package
πGreat to have this out @molbioevol.bsky.social and well done Hongfei Xu (not on BlueSky) for all the hard work
16.04.2025 15:53 β π 5 π 3 π¬ 0 π 0Review: Transcriptomics in the era of long-read sequencing www.nature.com/articles/s41... (read free: rdcu.be/efBjP) π§¬π₯οΈπ§ͺ
29.03.2025 08:57 β π 32 π 12 π¬ 1 π 0A local synteny visualization with 3 genes across 4 genotypes.
Using my Tidyverse local synteny visualization tools first time in 3 months. This a biosynthetic gene cluster with 2 P450s and a O-methyltransferase. Visualized across assemblies for 4 cultivars.
GitHub: github.com/cxli233/Tidy...
Our review on k-mers + pop gen is now published!
doi.org/10.1093/molb...
Friends, LiftOn is now published in @genomeresearch.bsky.social! LiftOn maps genes across genomes using a protein-centric, homology-based approach with both DNA & protein alignments
@stevensalzberg.bsky.social Mihaela Pertea, Jakob Heinz, Alaina Shumate, Celine Hoh, Alan Mao
doi.org/10.1101/gr.2...
Resulting from an @snsf-ch.bsky.social SPARK grant this took some time to mature, but the outcome is very imformative and builds a foundation for where to head next - how to liberate facts/information locked in the published literature www.biorxiv.org/content/10.1... #textmining #biodiversity
25.02.2025 19:31 β π 21 π 12 π¬ 1 π 0Bitte am Sonntag wΓ€hlen gehen! Noch nie war eine Wahl so wichtig fΓΌr Deutschlands Zukunft.
#Btw2025
Wow. This is sooo good. Echoing @urbanevol.bsky.social this userβs manual for Ne should be required reading for popgen and conservation genetics folks. onlinelibrary.wiley.com/doi/10.1111/...
17.02.2025 18:26 β π 89 π 41 π¬ 1 π 4With @katiejenike.bsky.social and a bunch more of our fellow k-mer enthusiasts, we put together a manuscript on k-mers in biodiversity genomics. A guide if you will, that covers k-mers from basics to some really funky stuff...
genome.cshlp.org/content/35/2...
Finally ready to see the world! Theories of balancing selection - past, present and future: www.biorxiv.org/content/10.1... A true collaborative effort that brought together theoreticians and empiricists, models, data, and fresh perspectives on how balancing selection can shape genetic variation.
14.02.2025 16:49 β π 29 π 15 π¬ 2 π 1OlΓ‘, Brasil! π§π· Interested in a research stay in Germany? Are you currently a postdoc at a uni or research institution in Brazil? Our CAPES #Fellowship offers you funding for a #research stay for 6-24 mth! Join our info event on 18 Feb! www.humboldt-foundation.de/en/connect/i...
13.02.2025 15:08 β π 26 π 10 π¬ 0 π 1Principled PCA separates signal from noise in omics count data www.biorxiv.org/content/10....
13.02.2025 15:15 β π 12 π 2 π¬ 0 π 0ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity π§¬π₯οΈπ§ͺ
Paper: https://www.biorxiv.org/content/10.1101/2025.02.06.636847v1
#Rstats Code: https://github.com/Yunuuuu/ggalign
Docs: https://yunuuuu.github.io/ggalign/
Book (Quarto): https://yunuuuu.github.io/ggalign-book/
New paper with Sarthak Mishra! Maybe it will bring you some joy given all this (waves arms around).
"Estimating recombination using only the allele frequency spectrum"
1/2
www.biorxiv.org/content/10.1...
What is a differentially expressed gene? https://www.biorxiv.org/content/10.1101/2025.01.31.635902v1 π§¬π₯οΈπ§ͺ https://github.com/Morris-Research-Group/bayexpress
05.02.2025 21:00 β π 38 π 11 π¬ 1 π 0A new tool, vcfsim, developed by Paimon Goulart, a stellar undergraduate researcher in my lab! vcfsim allows for the quick and easy simulation (via parameterized msprime simulations) of "all-sites" vcfs, with arbitrary ploidy and amounts of missing data.
www.biorxiv.org/content/10.1...
CASTER: Direct species tree inference from whole-genome alignments https://www.science.org/doi/10.1126/science.adk9688 π§¬π₯οΈπ§ͺ https://github.com/chaoszhang/ASTER
31.01.2025 21:00 β π 15 π 6 π¬ 0 π 0locuszoomr: an R package for visualising publication-ready regional gene locus plots https://academic.oup.com/bioinformaticsadvances/advance-article/doi/10.1093/bioadv/vbaf006/7958574 π§¬π₯οΈπ§ͺ #Rstats https://github.com/myles-lewis/locuszoomr
28.01.2025 21:00 β π 18 π 6 π¬ 0 π 0doubletrouble: an R/Bioconductor package for the identification, classification, and analysis of gene and genome duplications https://pubmed.ncbi.nlm.nih.gov/39862387/ π§¬π₯οΈπ§ͺ #Rstats https://github.com/almeidasilvaf/doubletrouble
28.01.2025 16:30 β π 14 π 5 π¬ 1 π 0In a new Science study, researchers present CASTER, a tool that uses arrangements in DNA sequences known as site patterns to infer βspecies trees,β which are diagrams that depict the evolutionary relationships among species.
Learn more:
Lestrimelitta robber bees standing on the entrance tube
Melipona flavolineata stingless bee guards standing on their nest entrance tube
π 3-year Postdoc position π
Join us @bristolbiosci.bsky.social to study the impacts of parasitic bees on tropical bee communities using eDNA, SNPs & field-based surveys.
π
Deadline: 23 Feb 2025
πVibrant city
π Collaboration with USP π§π·
π Details here: tinyurl.com/586u7vau
@leverhulme.bsky.social
Fantastic having @tegangaetano.bsky.social visit @unimainz.bsky.social and a nice experience to develop scientific links between my adopted homeland π©πͺ and the country I get most mistaken for π΄σ §σ ’σ ³σ £σ ΄σ Ώ π
24.01.2025 16:36 β π 4 π 0 π¬ 0 π 0