Jaime Martinez-Urtaza's Avatar

Jaime Martinez-Urtaza

@jaimemurtaza.bsky.social

(Meta)genomics & evolution of human pathogens. Global health in a planet facing a climate emergency. All opinions are mine. Professor of Genetics at the Universitat Autònoma de Barcelona

103 Followers  |  290 Following  |  9 Posts  |  Joined: 25.11.2024  |  2.161

Latest posts by jaimemurtaza.bsky.social on Bluesky

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Strain displacement in microbiomes via ecological competition - Nature Microbiology Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.

Strain displacement in microbiomes via ecological competition
#microbes #ecology #microSky

www.nature.com/articles/s41...

08.11.2025 01:25 — 👍 8    🔁 3    💬 0    📌 0
Hybridization between previously isolated lineages is main source of diversity within the population.

Hybridization between previously isolated lineages is main source of diversity within the population.

Hybridisation breaks species barriers in long-term coevolution of a cyanobacterial population.
buff.ly/EaJskBA

02.11.2025 23:28 — 👍 5    🔁 7    💬 0    📌 0
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From clonality to complexity: a journey through microbial ecology and evolution Nature Reviews Genetics, Published online: 30 October 2025; doi:10.1038/s41576-025-00910-6Jaime Martinez-Urtaza reflects on two papers by Smith et al., who found that bacteria exist along a continuum from clonal to recombining populations, and introduced the concept of an ‘epidemic’ microbial population structure.

New online! From clonality to complexity: a journey through microbial ecology and evolution

30.10.2025 14:28 — 👍 2    🔁 2    💬 0    📌 0
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🚨 JUST PUBLISHED 🚨

⚠️ The 2025 @lancetcountdown.bsky.social report reveals climate change inaction is costing lives and livelihoods, and harming the economy.

❤️‍🩹 Protecting people’s health demands all hands on deck.

Read more: www.lancetcountdown.org/2025-report/ #LancetClimate25

29.10.2025 00:23 — 👍 129    🔁 84    💬 0    📌 13
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Natural directed evolution in gut microbiota Bacteria undergo rapid genetic changes that are selected by alterations in the human gut environment

Bacteria undergo rapid genetic changes that are selected by alterations in the human gut environment.

Learn more in a new #SciencePerspective: https://scim.ag/4qaRWNh

17.10.2025 19:15 — 👍 36    🔁 9    💬 1    📌 0

please read this thread - even if you don;t get time to read the paper!!!!! just the best - great work, really really great.

25.09.2025 21:48 — 👍 7    🔁 3    💬 1    📌 0
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Vibrio2026: The International Meeting on the Biology of Vibrios Fourwaves - Vibrio2026: The International Meeting on the Biology of Vibrios

Delighted to announce that The International Meeting on the Biology of Vibrios will be back next year!

Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists!

event.fourwaves.com/vibrio2026/p...

18.09.2025 18:24 — 👍 26    🔁 14    💬 0    📌 1
"Health losses attributed to anthropogenic climate change," a brief communication in the journal Nature Climate Change. There's a map showing regions of the world, and pie charts of relevant studies as they apply to different health impacts like "heat-related deaths" and "maternal and child health"

"Health losses attributed to anthropogenic climate change," a brief communication in the journal Nature Climate Change. There's a map showing regions of the world, and pie charts of relevant studies as they apply to different health impacts like "heat-related deaths" and "maternal and child health"

🚨 NEW: Climate change is already causing 30,000 deaths per year - a global annual economic loss of $100-350B USD - but the true damage is probably 10x higher. Out TODAY in Nature Climate Change: the first systematic look at the science of "health impact attribution" 🔓 www.nature.com/articles/s41...

17.09.2025 11:57 — 👍 875    🔁 503    💬 22    📌 36

Our “Less is more” story is out! 🚀 We reveal how gene loss shaped the adaptive evolution of pandemic Vibrio parahaemolyticus, highlight a potentially general mechanism across bacteria. Huge thanks @danielfalush.bsky.social @campy-bara.bsky.social @jaimemurtaza.bsky.social & all coauthors

27.08.2025 13:06 — 👍 10    🔁 5    💬 0    📌 0
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Wave succession in the pandemic clone of Vibrio parahaemolyticus driven by gene loss - Nature Ecology & Evolution A combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows that gene loss in the putrescine utilization pathway has enhanced biofilm formation an...

Combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows sheds light on how a pandemic clone of Vibrio parahaemolyticus was able to spread worldwide

www.nature.com/articles/s41...

27.08.2025 11:04 — 👍 18    🔁 10    💬 0    📌 2

Beautiful work on the emergence of the pandemic clone of V. parahaemolyticus

27.08.2025 11:21 — 👍 15    🔁 6    💬 0    📌 0
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How to get introgressed fragments in genomic data? Everything you always wanted to know you find in our review in @cp-trendsgenetics.bsky.social, led by Xin Huang:
doi.org/10.1016/j.ti...

24.07.2025 02:04 — 👍 25    🔁 11    💬 0    📌 0
The History of the Panmictic Population Concept and Its Legacy in Contemporary Population Genetics ABSTRACT The panmictic population concept is at the heart of population, evolutionary and conservation genetics. However, in nature, true panmictic populations are vanishingly rare. As an idea conce...

Really excited to share the first paper from my PhD - it’s all about assumptions in modelling and the history of early population genetics… 🧵

doi.org/10.1111/ahg....

01.08.2025 22:47 — 👍 38    🔁 12    💬 1    📌 0
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Long et al. integrate population genomics, experimental evolution, and environmental modeling to elucidate the evolutionary responses to climate change in Populus lasiocarpa.

This study has made the July cover of MBE.

🔗 doi.org/10.1093/molbev/msaf116

#evobio #molbio

20.07.2025 06:14 — 👍 4    🔁 3    💬 0    📌 0
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Evolution of hunt, kill, devour in a Vibrio ecospecies Bacterial ecospecies are a recently recognized genetic structure that is hypothesized to arise by complex adaptation to a new niche. Using coadaptation analysis as a foundation for laboratory experime...

Happy to share the preprint from here in Shanghai, together with @danielfalush.bsky.social, as well as with team Zhizhou Jia, Huqi Wen, and Zhe Xie!

www.biorxiv.org/content/10.1...

30.06.2025 07:45 — 👍 28    🔁 15    💬 1    📌 0
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Cleanifier: A fast and lightweight k-mer based tool to remove contamination in microbial sequence data. #MicrobialSequences #ContaminationRemoval #Kmers #Genomics #Bioinformatics @biorxivpreprint
www.biorxiv.org/content/10.1...

01.07.2025 08:31 — 👍 6    🔁 3    💬 1    📌 0
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Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer - Nature Medicine An analysis of 18 metagenomic datasets of individuals with colorectal cancer, adenomas and healthy controls yields improved cancer prediction accuracy based solely on gut metagenomics, as well as the ...

🥁NEW publication from our lab:
the largest meta-analysis of gut microbiome associations with CRC!

www.nature.com/articles/s41...

🧵⬇️

1/6

03.06.2025 10:43 — 👍 42    🔁 22    💬 3    📌 1
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Longitudinal profiling of low-abundance strains in microbiomes with ChronoStrain - Nature Microbiology ChronoStrain accurately profiles low-abundance strains in longitudinal samples by jointly modelling nucleotide sequencing errors, strain presence/absence and the temporal information associated with e...

🚨 Out now!

Chronostrain - a method to profile low abundance strains in longitudinal microbiome samples 🦠💻

@travis.gibsonlab.io @younhk.bsky.social @gibsonlab.io @harvardmed.bsky.social @broadinstitute.org

#MicroSky 🦠 #MicrobiomeSky

www.nature.com/articles/s41...

06.05.2025 18:54 — 👍 41    🔁 29    💬 0    📌 2
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Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution - Nature Biotechnology The evolution of microbial strains is revealed by analyzing structural variation.

Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution

@natbiotech.nature.com from @microbiome.bsky.social

www.nature.com/articles/s41...

17.05.2025 07:35 — 👍 20    🔁 5    💬 0    📌 0
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Release RAxML-NG v2.0-beta2 · amkozlov/raxml-ng Main new features Adaptive tree search heuristic (Togkousidis 2023) , (Togkousidis 2024) Multiple fast branch support measures Integrated model testing Full Changelog: 1.2.2...2.0-beta2

RAxML-NG v2.0 beta is here

github.com/amkozlov/rax...
Features
1. Difficulty prediction
academic.oup.com/mbe/article/...
2. Adaptive search academic.oup.com/mbe/article/...
3. Early Stop
www.biorxiv.org/content/10.1...
4. Model selection
5. Rapid bootstrapping academic.oup.com/mbe/article/...

15.05.2025 05:35 — 👍 63    🔁 34    💬 0    📌 1
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Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes - Nature Biotechnology A workflow using conserved amino acid domains identifies viruses in sequence data at single-cell resolution.

Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes - @lauraluebbert.com @lpachter.bsky.social go.nature.com/4lGrSY3

22.04.2025 13:04 — 👍 44    🔁 14    💬 3    📌 1
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Genomic and genetic insights into Mendel’s pea genes - Nature Characterization of the genetic architecture underlying the 7 pairs of contrasting traits studied by Mendel and the over 70 additional agronomic traits in pea (Pisum sativum) reveals their m...

New genomic & genetic insights into Mendel’s pea genes, including previously uncharacterised alleles

159 years after Mendel published his work, this is a real delight (especially for a geneticist)

🧪
@nature.com

www.nature.com/articles/s41...

24.04.2025 05:37 — 👍 139    🔁 75    💬 2    📌 6

This new Hifiasm --ont option is amazing. It worked like a charm for us in the nanopore adaptive sampling based assembly paradigm we introduced in a preprint recently.

www.biorxiv.org/content/10.1...

19.04.2025 02:31 — 👍 16    🔁 6    💬 2    📌 0
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Our rising seas. This is only going to get harder to ignore.

This NASA visualization was created by svs.gsfc.nasa.gov/5520/

13.04.2025 02:21 — 👍 926    🔁 436    💬 29    📌 43
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Ocean heat content in 2024 - Nature Reviews Earth & Environment Global full-depth ocean heat content (OHC) gain since 1960 reached a record 452 ± 77 ZJ in 2024. OHC was 15 ± 9 ZJ higher than in 2023, primarily associated with warming in the Atlantic and Indian Oce...

Ocean heat content (OHC) in 2024

Global full-depth OHC gain since 1960 reached a record 452 ± 77 zetajoules (ZJ) in 2024. OHC was 15 ± 9 ZJ higher than in 2023, primarily associated with warming in the Atlantic and Indian Oceans

1 ZJ = 1,000,000,000,000,000,000,000 J
www.nature.com/articles/s43...

13.04.2025 06:18 — 👍 65    🔁 38    💬 2    📌 1
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The value of gene duplication Experiments in bacteria test a 50-year-old hypothesis on how duplicate genes help living things evolve.

Experiments in bacteria test the 50-year-old Ohno’s hypothesis that having duplicates of a gene (true for about 50% of them) allows evolution to accelerate. #EvoBio #Evolution

10.04.2025 15:12 — 👍 10    🔁 2    💬 0    📌 0
A phylogeny of the 7 ape genomes that have now been completed from "T2T", with Homer Simpson representing mankind.

A phylogeny of the 7 ape genomes that have now been completed from "T2T", with Homer Simpson representing mankind.

A project five years in the making, we've now published complete "T2T" genomes for six additional ape species! It turns out that finishing (and analyzing) six genomes is slightly more work than one... doi.org/10.1038/s415...

09.04.2025 21:31 — 👍 156    🔁 77    💬 5    📌 3

So glad this is finally out. The method has been instrumental in allowing us to compress the AllTheBacteria data - ~2 million bacterial genomes shrink from 3Terabytes (gzipped) to 100Gb using phylogenetic compression. Great work by @brinda.eu

09.04.2025 22:27 — 👍 126    🔁 51    💬 4    📌 1

It's finally out!!!! Our review on long-reads transcriptomics was published in @natrevgenet.bsky.social!! You can have a look at the paper here rdcu.be/efugl! We hope you like it 😀

28.03.2025 11:25 — 👍 27    🔁 10    💬 2    📌 0
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Anthropogenic activity and climate change exacerbate the spread of pathogenic bacteria in the environment Climate change and human activity will increase global richness and abundance of pathogenic bacteria, threatening public health.

Anthropogenic activity and climate change exacerbate the spread of pathogenic bacteria in the environment | Science Advances www.science.org/doi/10.1126/...

28.03.2025 06:49 — 👍 2    🔁 0    💬 0    📌 0

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