Severin Uebbing

Here, we report a detailed protocol of H3K27-ac ChIP-seq in human cells with chromatin from an ancestral species as a spike-in control.

No, Drosophila is not ancestral to human. Not in any meaning of the word.

26.11.2025 11:39 — 👍 0    🔁 0    💬 0    📌 0

🧬 10 @dfg.de-funded PhD positions at @goettingen-campus.de 🧬
❗Focus: Evolution of gene regulatory networks & Wnt signaling in emerging models (insects, snails, flatworms, cnidarians).
💻 Methods: 'Omics, Bioinformatics, CRISPR/RNAi & Imaging.
📌Start: June 2026.
#EvoDevo #Genomics #Bioinformatics

18.11.2025 14:04 — 👍 10    🔁 8    💬 1    📌 1

Posnien - Georg-August-Universität Göttingen Webseiten der Georg-August-Universität Göttingen

🧬 PhD Position: Evolutionary & Comparative Genomics 🕷️
Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13).
We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes!
More infos 👇 and s.gwdg.de/eDrAAY
#Evolution #Genomics #Bioinformatics

18.11.2025 07:04 — 👍 23    🔁 29    💬 2    📌 0

Q: Name and describe a major challenge for unravelling enhancer function; include a description of an approach or method to tackle the challenge!
Student: It's difficult to what an enhancer's target gene is. AI models can be used to predict interactions! 🙈

30.09.2025 12:58 — 👍 1    🔁 0    💬 0    📌 0

Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development Yim et al. use single-cell transcriptomics to elucidate the molecular outcomes of Chd8 haploinsufficiency in the mouse cortex. Their results provide insight into dynamic, cell-type-biased transcriptio...

Out in Cell Genomics: A comprehensive analysis of the cell-type-specific effects of CHD8 loss of function on gene expression in the embryonic and juvenile mouse cortex. Thread 🧵:
www.cell.com/cell-genomic...

23.09.2025 17:18 — 👍 22    🔁 9    💬 2    📌 1

Genetic Characterization of the Cell Types in Developing Feathers, and the Evolution of Feather Complexity We used single cell sequencing to investigate the cell types of developing chicken feathers. From these data, we are able to describe the transcriptional profile of feather cell types, look at their ....

My feather cell type paper is finally out! doi.org/10.1111/ede.... We’ve packed a ton of stuff into this paper but I’ll go through some highlights in this thread!

26.08.2025 17:22 — 👍 54    🔁 28    💬 2    📌 1

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!

These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.

Save and share the post!

13.05.2025 19:55 — 👍 677    🔁 349    💬 32    📌 6

Deutsche im Ausland - Die Bundeswahlleiterin Informationen für Deutsche im Ausland zur Teilnahme an der Bundestagswahl 2021.

Just a reminder for Germans abroad that you need to re-register to vote in the Federal Election, even if you didn't move houses since 2021 (yes, I'm a political scientist and had to google this). Here are the docs you need: www.bundeswahlleiterin.de/bundestagswa.... (1)

13.01.2025 19:56 — 👍 105    🔁 79    💬 1    📌 0