Janet Iwasa

Janet Iwasa

@jiwasa.bsky.social

Molecular animator, cell biologist, biochemist, science communicator. Head of the Animation Lab, Director of the Stark Science Learning Center at the University of Utah, and writer of the RCSB PDB Molecule of the Month

2,447 Followers 195 Following 31 Posts Joined Dec 2023
2 days ago
Structural studies have provided new insights into lenacapavir's unique mechanism of action. Using electron cryotomography, researchers found that treatment of intact HIV capsids with lenacapavir causes capsids to rupture, with ruptures occurring first in areas of the capsid with the highest level of curvature. The walls of lenacapavir-treated capsids were observed to flatten during early time points and fragment over the course of the experiment. This process is shown in the animation, created by Rachel Torrez in collaboration with Owen Pornillos (University of Utah). The animation was created using pdb_00009pry and pdb_00009y7j and their corresponding models in the EM Data Bank, EMD-71816 and EMD-72657.

Researchers found that treatment of intact HIV capsids with lenacapavir causes capsids to rupture, with ruptures occurring first in areas of the capsid with the highest level of curvature. #ASBMB2026 #ASBMB26
Watch in 3D at PDB-101: pdb101.rcsb.org/motm...

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4 days ago
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I am excited to share with you an amazing video on the NLRP3 inflammasome pathway generated by talented Ann Liu from the Janet Iwasa lab @jiwasa.bsky.social @ann-hl.bsky.social. It shows the real structures of the pathway from #NLRP3, #ASC, #caspase-1, #GSDMD, #IL-1b, to #NINJ1. Enjoy!

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2 weeks ago
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Interested in molecular animation and in SF for #BPS2026? Stick around for the evening Structural Biology workshop (Rm 204/205/206) and my talk at 8:45pm (New Tools for Visualizing Dynamic Molecular Models) to learn about ProteinBlender! animation-lab.github.io/ProteinBlend...

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2 months ago

This was a really fun and interesting Molecule of the Month to do! Check out the article to see even more elaborate RNA-only structures.

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3 months ago
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Today, our animation synthesizing decades of research on actin-mediated endocytosis in budding yeast was published:
journals.biologists.com/jcs/article/...

The result of a fantastic Iwasa-Drubin lab collaboration.

@margotriggi.bsky.social @jiwasa.bsky.social
movie.biologists.com/video/10.124...

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3 months ago
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All #CellBio2025 attendees! Here’s our phenomenal lineup for our session on #SciArt & #SciComm: @ahnaskop.bsky.social, @jiwasa.bsky.social, @mag2art.bsky.social, @nat-prunet.bsky.social, and Julia Licholai. Please come by and spread the word! Huge thanks to @ascbiology.bsky.social and co-organizers!

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4 months ago
Check Your Health- Fun & Easy Ways to Talk to Your Family About Health History Did you know that talking about your family health history could be one of the most important traditions you make with your family? Health problems that tend to

Thanks, @kutv2news and @utahdhhs for the shout-out in your online story about learning your family's health history!
kutv.com/features/hea...
Check it out - our activities are FREE, easy and printable: learn.genetics.utah.edu/content/basi...

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5 months ago
Promotional infographic for the speakers of the first WALII symposium. This promo highlights Dr. Amy Gladfelter of the Duke University, and includes her bio, headshot, and link to her website.

Meet the speakers of the very first inaugural WALII Symposium: Exploring Life Without Water, happening Tuesday, Nov 18! 💧

To Learn More about the symposium: walii.science/virtual-symp...

To Learn More about Dr. Amy Gladfelter: www.cellbio.duke.edu/amy-gladfelter

@gladfelterlab.bsky.social

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7 months ago

I'm so honored to receive the 2025 Bruce Alberts Award for Excellence in Science Education. Thank you @ascbiology.bsky.social and I look forward to this year's annual ASCB meeting in Philly!

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7 months ago
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Licensed to live | Cold Spring Harbor Laboratory The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

“In bone marrow alone ~500 million cells are born every min” says Bruce Stillman. Each must duplicate 2+ meters of DNA to avoid errors that can cause cancer & autism. See more from Stillman, @crick.ac.uk’s John Diffley & @uuhsresearch.bsky.social's @jiwasa.bsky.social
www.cshl.edu/licensed-to-...

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7 months ago

The Animation Lab will be giving an animation workshop and table demos, and the GSLC will have a table all day with demos! Come join us!

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8 months ago
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Almost fifty U of U researchers are giving over 80 demos, lab tours, workshops and talks for the public this Saturday, July 12th! Science-curious? We have something for everyone! 10am-4pm @utah.edu. Schedule and directions here: gslc.utah.edu/summer-scien...

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8 months ago
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Zoom In. Geek Out. Take a Backstage Pass to the Secret Life of Cells! Take a tour of the HSC Cell Imaging Core at 12, 1 or 2pm during Summer Science Day this Sat July 12th!
Find the full Summer Science Day schedule here: gslc.utah.edu/summer-scien...

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8 months ago

Yes - there are lots of IDRs in the MCMs. The animation focuses on their role in DNA binding (the close up) but they are thought to play other important roles as well. There's lots of discussion about IDRs in the review!

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8 months ago
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a dog is dancing in a room with the words happy dance written on the bottom . ALT: a dog is dancing in a room with the words happy dance written on the bottom .

So grateful to be posting happy work-related news. First- I'm now tenured! Thank you @uofubiochem.bsky.social, @utah.edu, and Animation Lab collaborators! Also, 2 of GSLC's (@learngenetics.bsky.social) terminated science education grants were reinstated! AND Summer Science Day is next week!

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8 months ago
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One week until Summer Science Day! Everyone is welcome to visit @UofUHealth for lab tours, public-friendly talks, demos, and workshops! Saturday July 12th from 10am-4pm. Check out our action-packed schedule here: gslc.utah.edu/summer-scien...

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8 months ago
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Artists belong in science! Come to Summer Science Day & learn about:
+ How to draw dinosaurs!
+ Animating science w stop-motion animation!
+ Making a science comic!
+ Using 3D animation to bring science to life!
Sat 7/12, 10am-4pm. Free all-ages open house at the U. gslc.utah.edu/summer-scien...

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8 months ago
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Check out this new review (with animations, natch) of mechanisms of licensing origins of DNA replication - a wonderful (and continuing!) collaboration with Bruce Stillman @cshlnews.bsky.social and John Diffley @crick.ac.uk! www.nature.com/articles/s41...

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8 months ago

Working with collaborators at the Crick Institute and the University of Utah, CSHL's President and CEO Bruce Stillman explores how pre-replicative complexes (pre-RCs)—even earlier than ORCs—assemble to initiate DNA replication in all plants, animals, and fungi.

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8 months ago
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You're trying to fill the summer days. What do we have that might be interesting for you and your kids? How about electron microscopes? Glowing fish?! Pig lungs??!! Come to Summer Science Day at the U on Saturday, July 12. Free and open to the public! gslc.utah.edu/summer-scien...

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8 months ago
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U of U Summer Science Day is less than two weeks away! Come to the U on Saturday July 12th between 10am-4pm for lab tours, science demos, talks, and fun for all ages! Free and open to the public. Schedule will be coming out in the next day or two! gslc.utah.edu/summer-scien...

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9 months ago

Paper Published: A new chapter for Molecule of the Month
Read how @jiwasa.bsky.social has taken over as the series creator of stories about critically important biological macromolecules

pubs.aip.org/aca/sdy...

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9 months ago
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...and big thanks to @jiwasa.bsky.social for making this amazing video to illustrate the strand-sliding mechanism!

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10 months ago
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📣New FREE module drop!

In Genetic Tech Investigations, students explore what technologies like sequencing, mass spec, and others reveal about the process from genes to proteins.
➡️ teach.genetics.utah.edu/content/gent...

#ScienceTeachers #NGSS #Genetics #STEM

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10 months ago

Thanks to Rachel and Laura for this great collaboration!

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10 months ago
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Outside the lab, Laura likes to hang out with her almost 2- and 5-year olds!

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10 months ago
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The Dassama group uses detailed understanding of factors that enable interactions between biological molecules to provide insights that allow functional control of those molecules. Applications include host-microbe interactions and targeted control of disease-relevant proteins.

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10 months ago
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Meet Dr. Laura Dassama, an Assistant Professor at Stanford University. This illustration by Rachel Torrez showcases how the Dassama Group uses tools of chemistry and physics to provide molecular insights into complex biological processes.

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10 months ago

Thank you! I had a wonderful time at Augsburg. Getting to chat with students about their research was definitely a major highlight!

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10 months ago
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How ‘Science Interpreters’ Make Hidden Science Visible A cell animator and a museum designer tell us how they translate scientific findings into visual experiences.

Had a great time chatting with Flora Lichtman and Tim Lee @nhmu.bsky.social a couple of weekends ago here in SLC, and excited that our Science Friday @scifri.bsky.social piece will be airing today! www.sciencefriday.com/segments/sci...

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