The new Enabling Discovery through GEnomics (EDGE) Program page is posted. Please contact us at BIOEDGE@nsf.gov if you have questions. www.nsf.gov/funding/oppo...
08.12.2025 21:00 β π 80 π 53 π¬ 1 π 2@mikelove.bsky.social
Genetics, bioinformatics, comp bio, statistics, data science, open source, open science!
The new Enabling Discovery through GEnomics (EDGE) Program page is posted. Please contact us at BIOEDGE@nsf.gov if you have questions. www.nsf.gov/funding/oppo...
08.12.2025 21:00 β π 80 π 53 π¬ 1 π 2Ten years ago I had sent off my applications for faculty positions and found out that I was getting an interview with Chapel Hill Biostatistics.
08.12.2025 21:58 β π 21 π 0 π¬ 0 π 0Let us know, e.g. @stemang.bsky.social or I if you have any ideas for something to post re: use cases for tidyomics to share or to develop.
08.12.2025 17:29 β π 1 π 0 π¬ 0 π 0tidyomics project π R-bloggers!
www.r-bloggers.com/2025/10/the-...
Thanks to @stemang.bsky.social, Maria Doyle @bioconductor.bsky.social, @jhsanchez.bsky.social, Mengyuan Shen, Jonathan Carroll and others in tidyomics for testing and getting this up and running
Impressive!
04.12.2025 12:12 β π 0 π 0 π¬ 0 π 0Happy to see this out now in Cell Genomics: A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines: www.cell.com/cell-genomic...
03.12.2025 09:17 β π 26 π 9 π¬ 3 π 1en.wikipedia.org/wiki/Hertzsp...
03.12.2025 00:57 β π 0 π 0 π¬ 0 π 0"HertzsprungβRussell diagram. A plot of luminosity (absolute magnitude) against the colour of the stars ranging from the high-temperature blue-white stars on the left side of the diagram to the low temperature red stars on the right side."
Is this the coolest scatterplot?
03.12.2025 00:57 β π 35 π 0 π¬ 2 π 0Pretty neat to see our paper - led by @kr-maynard.bsky.social @lcolladotor.bsky.social on the 2021 list of most cited neuroscience papers π§ π¬π§ͺ
www.thetransmitter.org/publishing/w...
As promised, a longer thread on what I consider to be some of the most interesting and important contributions of this paper (1/10)
01.12.2025 21:20 β π 13 π 7 π¬ 1 π 2Consider submitting an abstract for an invited talk or poster at STATGEN 2026 by December 15th!
Amazing keynote speakers and statistical leaders in #genetics and #genomics! π
Hope to see you there! statgen26.emory.edu
π§ͺ 𧬠π₯οΈ π§ #statssky #imaging #SingleCell #spatial #omics #DigitalPathology
A nice paper on distilling AI-based splicing models into much simpler additive models:
"[...] the distilled models achieve this without modeling RNA structure or feature interactions, indicating that [AI]-based splicing models recognize exons primarily through simple additive sequence features."
High-quality mouse reference genomes [PacBio Long Read genomes of 17 strains] reveal the structural complexity of the murine protein-coding landscape, Cell Genomics. www.cell.com/cell-genomic... Genomes and annotations here: projects.ensembl.org/mouse_genomes/
02.12.2025 04:30 β π 28 π 9 π¬ 1 π 0π’ We are taking applications for our Postdoctoral Fellows Program at Harvard/DFCI!
πΉJoin a research group in our department
πΉCo-mentoring opportunities with 2+ faculty
πΉCollaborate with investigators beyond our department
πΉSalary starts at $75K
Apply here: t.co/B7SLZzQFKu
We are thrilled to announce the first official release (v0.1.8) of #π―π²π±π±π²πΏ, the successor to one of our flagship tool, #π―π²π±ππΌπΌπΉπ! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.
1/n
β° Only a few hours left to register!
Donβt miss todayβs Bioconductor Seminar Series session:
βDeep-learning-based Gene Perturbation Effect Prediction Does Not Yet Outperform Simple Linear Baselines.β
ποΈ December 2, 2025
π 9PM CET / 3PM EST / 12PM PST
π Register here: dfci.zoom.us/webinar/regi...
Excited to share work from my postdoc with @docedge.bsky.social and collaborators Matt Pennell and @jgschraiber.bsky.social, newly out over the weekend: www.biorxiv.org/content/10.1... (1/6)
01.12.2025 19:09 β π 60 π 28 π¬ 2 π 2Join EMBL's Interdisciplinary Postdoc Programme!
3 years funding, self-designed interdisciplinary project co-led between EMBL PI and PI in one of EMBL's actual, prospect or associate member states.
In particular: AI&Theory, use mathem. models, physics principles and AI
www.embl.org/about/info/p...
Excited to share that our article on accurate sample deconvolution of pooled snRNA-seq data using sex-dependent gene expression patterns is live on NAR Genomics and Bioinformatics! π
Check it out here: doi.org/10.1093/narg...
#NARGenomicsandBioinformatics #snRNAseq #Genomics #Bioinformatics
#Throwback π§ͺ
COMMENT | Metabolites are not genes β avoiding the misuse of pathway analysis in metabolomics
KS Lee, X Su & T Huan
Figure 1. Proteome compleasm scores for predicted transcripts by annotation method for vertebrates. The score is calculated as 1 β (number missing BUSCOs/total number of BUSCOs searched).
Joint distributions of number of predicted CDSs (normalized by number of NCBI predictions) over median predicted CDS length (nor- malized by median NCBI CDS length) for the reference species for each taxonomic group we examined, as well as M. musculus. Dotted lines indi- cate equivalence to NCBI annotation, such that methods that are closest to the intersection of those lines best approximate CDS length and number of NCBI annotations. A βPβ indicates that the method only makes protein- coding predictions.
Building better genome annotations across the tree of life
genome.cshlp.org/content/35/5...
TOGA, BRAKER3, and the RNA-seq assembler StringTie are top performers when benchmarking 12 different methods for 21 different species spanning vertebrates, plants, and insects.
PanSN-spec: Pangenome Sequence Naming
github.com/pangenome/Pa...
SuSiE 2.0: improved methods and implementations for genetic fine-mapping and phenotype prediction https://www.biorxiv.org/content/10.1101/2025.11.25.690514v1
28.11.2025 10:46 β π 19 π 8 π¬ 0 π 0Portrait photo Katy BΓΆrner
π£ Listen to the BIH Lecture " Multiscale Human Reference Atlas - An Ontological Bridge Between Anatomy and Disease" by Stiftung CharitΓ© visiting fellow Prof. Dr. @katyborner.bsky.social.
π
December 5, 2025, 12:00 - 1:00 pm, online via Zoom
β‘οΈ tinyurl.com/4p9cjhph
Foto Β© Andreas Bueckle
The GenomicRanges (github.com/BiocPy/GenomicRanges) package for Python got a major speed boost (v0.7.0+) thanks to Aaronβs blazing-fast C++ nclist interval indexing!
#Bioinformatics #Genomics #Bioconductor
I am very excited to share this book! It has been so much to collaborate on the project. We hope you find it useful!
21.11.2025 22:11 β π 22 π 7 π¬ 0 π 0We are excited to share our online book and preprint on βOrchestrating Spatial Transcriptomics Analysis with Bioconductorβ!
22.11.2025 12:38 β π 18 π 12 π¬ 1 π 0Many people hours, calls and messages later: OSTA is now βin (pre)printβ, though the real thing lives at bioconductor.org/books/OSTA.
Check it out, get in touch. We welcome any feedback, suggestions, wishes (& contributions).
Itβs been a joy working with you @estellayixingdong.bsky.social!
Representing EuroBioC2026 at the @abacbs.bsky.social Conference this week.
The next European @bioconductor.bsky.social Conference will be in Turku, Finland!
#ABACBS2025
#EuroBioC2026