Stig Ove Bøe

Stig Ove Bøe

@stigoveboe.bsky.social

Epithelial Mechanics, Active Matter, Biology and Physics

78 Followers 112 Following 8 Posts Joined Nov 2024
4 days ago
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PhD position: Quantitative Imaging & Cell Mechanics, studying how mechanics and cell dynamics shape early mammalian embryos. Interdisciplinary project (physics, dev. biology, ML) in Oslo. Deadline: 10 April 2026. See poster/QR for details. www.jobbnorge.no/en/available...

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1 month ago
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Postdoctoral Fellowship on Tissue mechanics and inflammatory processes in human skin | FINN.no Project titleNavigating the Tunnel: Keratinocyte Dynamics & Therapeutic Targeting of IL-17 in Hidradenitis Suppurativa Position summaryWe seek a motivated

Searching for a new job?
We’re hiring a Postdoctoral Fellow for an exciting new research project on Hidradenitis Suppurativa.
Apply now and please pass this on to anyone who might be interested!

www.finn.no/job/ad/44835...

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1 month ago
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Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de

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2 months ago
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Our review article is now available in Annual Review of Condensed Matter Physics: “Full-Integer Topological Defects in Polar Active Matter.” @luizaangheluta.bsky.social @emmalaang.bsky.social doi.org/10.1146/annu...

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4 months ago
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Active nematic pumps | PNAS Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alte...

Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps.

@pnas.org @ub.edu

www.pnas.org/doi/10.1073/...

#ActiveMatter #Microfluidics #SoftMatter

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4 months ago

Is it the "against the stream-cell" that is moving, or the other ones?

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5 months ago

fusilli bacteria?

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6 months ago
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New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...

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6 months ago
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Collective cell motion has many forms, but rotation is the coolest of them all.

I'm @onenimesa.bsky.social , and in this short🧵, I'll highlight some instances of global tissue rotation like this one from @BauschLab

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11 months ago
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Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...

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8 months ago
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New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.

The tissue morphogenesis logic, now engineered into living, programmable materials.

www.biorxiv.org/content/10.1...

#ActiveMatter #TissueEngineering

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8 months ago

Please don't throw more garbage into the ocean!

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8 months ago
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FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!

It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀

www.science.org/doi/10.1126/...

#DevBio #CellBio #Microscopy

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9 months ago
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What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?

I'm @juliaeckert.bsky.social. Let's explore some analysis software!‬

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9 months ago
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Development of a transgenic zebrafish embryo. Credit to Dr. Mario Mendieta-Serrano. #ZebrafishZunday 🧪

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9 months ago
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Happy #FluorescenceFriday!

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10 months ago
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The tip of the cantilever consists of a fluorescent bead that contacts the epiblast. Because we know the force necessary to bend the cantilever, we can perform mechanical assays by driving the bead across the embryo and measure in real time the force applied to the tissue.

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10 months ago
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Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...

🚨📣 New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics

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10 months ago
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Collective cell migration is fascinating!
Some tissues behave like fluids (motile), others like solids (jammed).

Check out some papers exploring this topic in this thread.

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10 months ago

"Exactly! Epithelia aren't just one thing. They can behave as fluids or solids and exhibit either nematic or polar order. Thank you @epimechfc.bsky.social for highlighting this!"

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10 months ago
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Trichoplax adhaerens is one of the simplest and most enigmatic animals on earth. Its body shows incredible fluidity, changing shape within minutes. In a recent visit by Andrea Pasini we had the chance to host and observe these amazing animals live.
[movie accelerated 3x; animal 0.5 to 1 mm in size]

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10 months ago
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B. Aigouy et al., Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila. Cell (2010). #EpithelialMechanics buff.ly/vH41dfH

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10 months ago
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New in Nature Physics! In a great collaboration with @junlab.bsky.social and my students Henrik Weyer & @lwuerthner.bsky.social, we show how Min proteins in E. coli self-organize into robust, efficient patterns ensuring accurate cell division across conditions.
📄 www.nature.com/articles/s41...

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10 months ago
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It's #MicroscopyMonday, so let's take a peek into the 🔬
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.

Dr. Inuoe premiered his research at MBL.

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11 months ago

How can organs regenerate fast? Bioelectricity helps -- by coupling sub-second electrical injury signals to regenerative proliferation.

First preprint from my potsdoc :D with @liujinghui.bsky.social @ritamateus.bsky.social @mpi-cbg.de and collaborators @mpipks.bsky.social @csbdresden.bsky.social

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10 months ago
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Topology-Driven Ordering of Flocking Matter New experimental and theoretical work solves the problem of how initially disordered ensembles of moving bodies can self-organize into coordinated flocks.

This paper was inspired by Amélie Chardac's studies on flocking colloidal particles:
journals.aps.org/prx/abstract...
It's pure Physics!

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10 months ago
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Flocking and active solid behavior of epithelial cells in our new study in @pnas.org
Great work of Y. Shen, J. O'Byrne and
@andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez!
| PNAS www.pnas.org/doi/10.1073/...

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10 months ago
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Biomechanics of orientationally ordered epithelial tissue Organogenesis involves large deformations and complex shape changes that require elaborate mechanical regulation. Models of tissue biomechanics have been introduced to account for the coupling between...

New paper on a field theory for coupling nematic ordering of the actin filaments with tissue elasticity.

arxiv.org/abs/2504.10689

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11 months ago
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Our new review on topological defects 🌀 in polar active matter is out on arXiv! Co-authored by Luiza Angheluta, Anna Lång, @emmalaang.bsky.social, and @stigoveboe.bsky.social. #ActiveMatter #TopologicalDefects #CollectiveBehavior
arxiv.org/abs/2504.03284

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1 year ago
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Integer topological defects offer a methodology to quantify and classify active cell monolayers - Nature Communications The orientation of elongated cells often rotates once around the center in tissue. Such structures are called +1 topological defects and play some roles in biological development. By inducing various ...

Congratulations to Zihui, Sano-san, and the team on this interesting work! They found that +1 topological defects attract neural progenitors—an observation that seems at odds with expectations for an extensile active nematic. www.nature.com/articles/s41...

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