Libusha Kelly

Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation - Nature Communications In this study, Dahmane et al use a method called cryo-electron tomography to uncover new details of how tick-borne flaviviruses transform cells into virus factories.

I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look!
#virology #teamtomo
www.nature.com/articles/s41...

What your breath says about the bacteria in your gut Metabolites in mouse and human breath correlate to gut-microbe populations and might be helpful in diagnosing disease.

The chemicals found in a person’s breath might reveal the identity of the microbes in their guts

go.nature.com/49TbAWP

Cell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbation - Nature Microbiology Without key cell cycle control genes, SAR11 cells experience aneuploidy and growth inhibition when exposed to changes in nutrients, carbon sources or temperature stress, a vulnerability that may repre...

Our latest. Led by the very talented @ahoiching.bsky.social

Cell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbation www.nature.com/articles/s41... #jcampubs 🌊

mvif 46 program

It's Friday!
...and a new #MVIF program is out! 🤩

Free registration: cassyni.com/s/mvif-46

Highlights:
🇺🇸 Rebecca L. Knoll
🇯🇵 Akito Sakanaka

Keynote:
🇺🇸 @simrouxvirus.bsky.social

⭐️ Talks:
🇦🇺 @jeremyjbarr.bsky.social
🇨🇦 @erikbakkeren.bsky.social
🇨🇳 Guanxiang Liang

Bioinformatician in Microbiome Research

🚨We are hiring a Bioinformatician who will be embedded in our lab and work with members of the NCCR Microbiomes at ETH Zurich, as well as the Institute of Microbiology.🚨
nccr-microbiomes.ch
jobs.ethz.ch/job/view/JOP...

A scientist wearing a lab coat is shown from behind, as she works at a fluorescence microscope.

Think outside the box and address the most pressing challenges in infection research with us!🧑‍🔬 We're offering 10 PhD positions at five HZI sites across Germany.
👉Don’t miss out—apply by February 28, 2026 and contribute to shaping the future of infection research
jobs.helmholtz-hzi.de/job/Braunsch...

What kinds of cognitions are possible? Are there discrete classes of cognition? Here's our new paper with @brigan.bsky.social @jordiplam.bsky.social @mitibennett.bsky.social @mkhochb.bsky.social and @drmichaellevin.bsky.social arxiv.org/abs/2601.12837 We explore basal, neural and human-AI spaces.

CELL MIGRATION LAB We study cell migration in health and disease

🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs).
Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬
Details in thread 🧵👇
#ScienceSky #Postdoc #AcademicJobs Please RT🫶

Engineering a streamlined virus-like particle for programmable tissue-specific gene delivery - Nature Communications Virus-like particles (VLPs) offer powerful gene delivery but face limits in targeting and complexity. Here, the authors create a streamlined SFV-based VLP platform that delivers mRNA, protein, or RNP ...

Today, Fish Hui Xian Poh presented this work by groups at the Chinese Academy of Sciences in Beijing. They dissected alpha virus SFV into nsPs, Capsid, Envelope to make VLPs for RNA or protein delivery - in some cases to target the blood-brain barrier. Very cool work!

doi.org/10.1038/s414...

Directors

Expressions of interest: Director at MPI EvolBio (f/m/d) — We invite expressions of interest from distinguished scientists in evolutionary biology with a bold, long-term research vision that complements our Institute. More information: www.evolbio.mpg.de/3856225/Dire...

My collaborator at University of Copenhagen, Anders Garm, is looking for a 3 year postdoc to work on bioluminescence, neurobiology and ecology of ctenophores. More information here:
candidate.hr-manager.net/ApplicationI...

Twist-ONT: Combining nanopore sequencing with the twist comprehensive viral research panel The Twist Comprehensive Viral Research Panel (Twist CVRP) is a probe-based hybridization capture enrichment method for whole-genome sequencing, design…

Interested in virome sequencing on @nanoporetech.com instruments? Check out our latest paper where we publish Twist-ONT, a modified protocol for the Twist Comprehensive Viral Research Panel (by @twistbioscience.com) so that it can be used with ONT.
www.sciencedirect.com/science/arti...
🧵1/7
🧪

A phage protein screen identifies triggers of the bacterial innate immune system - Nature Microbiology A library of 400 phage protein-coding genes is used to find a trove of antiphage systems, revealing systems that target tail fibre and major capsid proteins.

I’m thrilled to share our work on phage triggers of the bacterial immune system in its final form @natmicrobiol.nature.com www.nature.com/articles/s41...

🍄Transposon traffic in the mycocosmos🍄
Fascinating work reveals extensive horizontal TE transfer across fungi (@jromeijn.bsky.social, Iñigo Bañales & @mfseidl.bsky.social; doi.org/10.1016/j.cu...). I wrote a Dispatch to prime non-specialists,check it out here: doi.org/10.1016/j.cu....
#TEworldwide

TODAY

Screenshot from GRC portal confirming microbial population biology meeting June 27, 2027 in Andover, New Hampshire.

It’s officially happening folks! The Microbial Population Biology Gordon Research Conference is back in Andover, New Hampshire starting June 27th of 2027!
See you there!!

@wcratcliff.bsky.social @ksbakes.bsky.social @surtlab.bsky.social

#microsky #mevosky

Chiral catalysis-driven rotary molecular motors - Nature Chemistry The structural anisotropy necessary for the powered directional rotation of chemically fuelled molecular motors had previously been provided by chiral fuels or enzymes. Now it has been shown that asym...

Out today in @natchem.nature.com 😃 Huakui, @stefanborsley.bsky.social @benjaminoacid.bsky.social & co illustrate why catalysis-driven motors (like motor proteins) can't use designs based on light-driven motors or molecules-that-rotate-through-multi-reaction-sequences www.nature.com/articles/s41...

Last Friday over dinner, we talked with @svenklumpe.bsky.social and @jnoms.bsky.social about this very creative paper—and quickly went off track. Why? Because, as Sven put it, Vaults ( #Vaults ) remain the “siren 🧜‍♀️ of cell biology 🔬” intriguing and attractive, but maddeningly hard to figure out. 1/3

Locum Associate or Senior Editor Job Title: Locum Associate or Senior Editor (Chemical Biology / Biological Chemistry), Nature Chemistry Company: Nature Portfolio Contract Type: Full-time, Fixed Term (maternity leave cover) Location(...

We're hiring! We're looking for a Locum Editor to cover our chemical biology/biochem. The role can be located in either our London or Pune offices. Planned start date is June 1st. Closing date for applications is Feb 2nd. #chemjobs #chemsky springernature.wd3.myworkdayjobs.com/SpringerNatu...

Together with Jeroen Krijgsveld, we are looking for a postdoc to help us unlock single-cell proteomics (SCP) through the establishment of a scalable computational framework.

For more information, see the @hlsalliance.bsky.social Postdoc Program:
www.health-life-sciences.de/opportunitie...

PULSE postdoc program advances training through academic and industry secondments The SciLifeLab PULSE postdoc program, currently recruiting the second cohort of international talent to Swedish universities has two tracks: the academic and the entrepreneurial, industry supported…

SciLifeLab PULSE postdoc program focuses on innovative, fundamental, translational research. "The entrepreneurial track sparks the next generation of life-science ventures based on ground-breaking research at universities” says Kristian Sandberg. 🧪🌍

Apply today!
www.scilifelab.se/news/pulse-p...

Unveiling the global urban virome through wastewater metagenomics - Nature Communications Wastewater-based surveillance tends to focus on specific pathogens. Here, the authors mapped the wastewater virome from 62 cities worldwide to identify over 2,500 viruses, revealing city-specific virome fingerprints and showing that wastewater metagenomics enables early detection of emerging viruses.

#Viruses & #Epidemiology

Unveiling the global urban virome through wastewater metagenomics

@marionkoopmans.bsky.social @nathalieworp.bsky.social @bom1986.bsky.social

#metagenomics #viromics

"Machine learning-based lineage prediction from antimicrobial susceptibility testing phenotypes for Escherichia coli sequence type 131 clade C surveillance across infection types" Spoiler: the MDR ST131-C is pervasive in UTIs, underlying BSI trends. doi.org/10.1099/mgen... @microbiologysociety.org

Come work with us at Nature Chemistry! We're hiring a locum editor to handle our chembio content in London or Pune.

A chemically defined medium to support the growth of food-relevant Bacillus species

J Appl Microbiol from Dennis Nielsen #KUFood

academic.oup.com/jambio/advan...

New in JB: Khan, Palmer & Guan identified the genes for glucosaminyl phosphatidylglycerol biosynthesis, opening the way to study this lipid in P. aeruginosa.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

Mirdita Lab - Laboratory for Computational Biology & Molecular Machine Learning Mirdita Lab builds scalable bioinformatics methods.

My time in @martinsteinegger.bsky.social's group is ending, but I’m staying in Korea to build a lab at Sungkyunkwan University School of Medicine. If you or someone you know is interested in molecular machine learning and open-source bioinformatics, please reach out. I am hiring!
mirdita.org

We just released #anvio v9, "eunice" 🎉

This version represents over 2,000 changes in the codebase since v8, increasing the total number of programs in the anvi'o ecosystem to 176.

Read the release notes:

github.com/merenlab/anv...

Visit our up-to-date web page:

anvio.org

Deadline is approaching (Feb 9) to apply for a PI position at Institut Pasteur. Come join us and contribute to an amazing scientific environment!!!

Eco-evolutionary genomics of microorganisms Genomic approaches have transformed how we study microorganisms, which shape nearly every aspect of life on Earth.

Really happy to see Nature Reviews Genetics dedicate a whole focus issue to the eco-evolutionary genomics of microorganisms. Great to see this field getting the spotlight!

www.nature.com/collections/...