@bobcoelingh.bsky.social
PhD student at Utrecht University Interested in virology and cryo-EM
Had a great time hosting @proteincapsid.bsky.social over the past few days. Thanks for the exciting lecture and for sharing your tomography expertise. Until next time!
14.11.2025 15:45 — 👍 11 🔁 2 💬 0 📌 1Thrilled, and admittedly relieved, to see this major investment in Dutch #cryoEM become reality! 🇳🇱🔬
Honoured to be a co-applicant on this national initiative and very excited for the opportunity to advance our work in cellular structural virology! 🦠
www.uu.nl/en/news/33-m...
"Development of a live-cell imaging assay to elucidate spatiotemporal dynamics of extracellular vesicle fusion with target cells"
www.biorxiv.org/content/10.1...
Interested in our recent norovirus NS3 work? 👇
Join us to dig deeper!
I'm recruiting a PhD candidate to investigate NS3's role in viral replication and assembly using #cryoEM, #cryoET, and other complementary techniques.
🔗 tinyurl.com/4f3t3aae
Please share! 🙏
Latest preprint from the lab, many years in the making!
By combining #cryoEM with #AlphaFold3 modelling, we propose that norovirus NS3 forms a transmembrane RNA translocase.
This could have big implications for our understanding of viral replication & assembly (🧵)
www.biorxiv.org/content/10.1...
Think coronavirus spikes have run out of surprises? Think again.
Our latest preprint dives into the highly unusual spikes of marine mammal coronaviruses.
www.biorxiv.org/content/10.1...
This #cryoEM study was led by @viralfusion.bsky.social, with key contributions from an amazing team.
I’m delighted that we could contribute the #cryoEM data to this incredible antiviral discovery project from the group of @neytsjohan.bsky.social 💊
"A coronavirus assembly inhibitor that targets the viral membrane protein"
www.nature.com/articles/s41...
A huge congrats to everyone involved! 🎉
More picornavirus research from us! 😄
16.03.2025 15:50 — 👍 18 🔁 6 💬 1 📌 1
Latest #virology research from the lab! 👇
Using genetic approaches and live-cell imaging, we show that the viral 2A protease plays a critical role in subverting antiviral responses and establishing a favorable host environment to expedite enterovirus replication.
www.biorxiv.org/content/10.1...
I’m looking for a postdoc to join my team under a recently funded ERC Starting Grant.
If you’re passionate about structural #virology and have experience in #cryoEM SPA and/or #cryoET, get in touch!
Application deadline: January 19th.
Please share with your networks 🙏
Job link: tiny.cc/7v33001
Streamlining segmentation of cryo-electron tomography datasets with Ais pubmed.ncbi.nlm.nih.gov/39704648/
21.12.2024 23:30 — 👍 1 🔁 2 💬 0 📌 0
Poliovirus keeps popping up in European wastewater, perplexing and worrying scientists www.science.org/content/arti...
12.12.2024 17:13 — 👍 35 🔁 8 💬 1 📌 0Amazing science at the Science for Life meeting in Utrecht. The talk by Julia Mahamid was incredible; it most definitely helped me to secure a poster prize too!
02.12.2024 19:14 — 👍 10 🔁 2 💬 0 📌 0me too @danielhurdiss.bsky.social
14.11.2024 12:27 — 👍 1 🔁 0 💬 0 📌 0
Excited to share our first preprint of 2024! 🎉
researchsquare.com/article/rs-3...
This study focuses on PDCoV, an emerging enteric pathogen.
We generated anti-spike mAbs & investigated their inhibitory mechanisms using structural & functional studies.
#virology #cryoEM
Our #TeamTomo adventure continues! 🔬
Here is Bob's first attempt running MemBrain-seg on one of his tomograms 😍
@bobcoelingh.bsky.social
