Iñaki Ruiz-Trillo's Avatar

Iñaki Ruiz-Trillo

@multicellgenome.bsky.social

Leading a research lab with Elena Casacuberta. We aim to unravel how #protists evolved into multicellular animals. #Multicellularity #Ichthyosporea #holozoans #filastereans #development #diversity #genomes #modelsystems https://multicellgenome.com

1,841 Followers  |  1,734 Following  |  126 Posts  |  Joined: 11.11.2024  |  2.3155

Latest posts by multicellgenome.bsky.social on Bluesky

Buenísimo Sergio! & thanks! 📱🦠 But then, we have outsourcing. We argue that animals outsourced metabolic costs (losing genes for amino acids) to their food. Smartphones ffloaded data/processing to the Cloud. The goal of the analogy isn't to fit perfectly, but to show us where the new questions are!

19.01.2026 08:44 — 👍 1    🔁 0    💬 0    📌 0
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CONGRESO FUTURO 2026 | SÁBADO 17 DE ENERO (IDIOMA ORIGINAL) YouTube video by Congreso Futuro

What do unicellular organisms teach us about cancer? 🦠 Elena took the stage at @congresofuturo.bsky.social (LatAm's biggest science event!) to explain the connection.🎥 Watch Elena's talk:
www.youtube.com/live/eyEYS3a...
@ibe-barcelona.bsky.social @csic.es @prbb.org @icreacommunity.bsky.social

19.01.2026 08:36 — 👍 9    🔁 2    💬 1    📌 0

Congrats Roberto!!

18.01.2026 07:29 — 👍 0    🔁 0    💬 1    📌 0
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🎓Gonzalo defended his PhD on #Capsaspora aggregation & animal origins. Privilege to co-supervise with Koryu—watching a former trainee mentor the next generation is so cool! Thanks Núria, Nick & Cristina for the stimulating discussion! @icreacommunity.bsky.social @ibe-barcelona.bsky.social

17.01.2026 22:07 — 👍 9    🔁 0    💬 0    📌 0
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Elena presenting our work on animal origins at Universidad Católica del Norte, Antofagasta, as part of the #CongresoFuturo #multicellularity #ichthyosporeans @prbb.org @csic.es @csicdivulga.bsky.social @csiccat.bsky.social @ibe-barcelona.bsky.social

16.01.2026 21:51 — 👍 11    🔁 0    💬 0    📌 0
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The EMBO Journal Launched in 1982, The EMBO Journal is EMBO’s flagship publication, recognised worldwide for its originality, breadth, and enduring contributions to molecular ...

Link: bit.ly/4jKdkpV

15.01.2026 10:59 — 👍 4    🔁 0    💬 0    📌 0

What was missing wasn't the parts, but the "Animal Operating System" (Animal OS). We propose the innovation was the integration and repurposing of these pre-existing components. And we use a powerful scientific tool (analogies) to maje our argument. We hope you will enjoy it!

15.01.2026 10:59 — 👍 7    🔁 0    💬 1    📌 0

Think of the smartphone. It didn't appear out of nowhere. First came batteries, chips, camera, mp3, etc developed independently for years. Then came integration into one single entitity! The same happened with animals: unicellular ancestors already had most of the mechanisms to be #multicellular

15.01.2026 10:59 — 👍 5    🔁 0    💬 1    📌 0

For decades, it was thought animals arose via a rapid burst of genetic innovation. But by sequencing their closest unicellular relatives (our beloved protists), we now know most of those genes originated before animals evolved. We have tons of data on that! 😀

15.01.2026 10:59 — 👍 6    🔁 1    💬 1    📌 0
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📱Is the origin of animals comparable to the origin of the smartphones? Yes! See our new review in @embojournal.org where we show how important it was the new "Operating System" (animalOS)for animals to evolve! with @ricardsole.bsky.social, Nick and Elena @ibe-barcelona.bsky.social @csic.es @prbb.org

15.01.2026 10:59 — 👍 41    🔁 15    💬 4    📌 1

Cool!

08.01.2026 19:20 — 👍 1    🔁 0    💬 0    📌 0
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Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history Sponges have a cryptic Ediacaran history because ancestral sponges were soft-bodied and had low fossilization potential.

Our latest: Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history, led by @meleonora-rossi.bsky.social with help from friends @bristolpalaeo.bsky.social including @anariesgo.bsky.social @evopalaeo.bsky.social Davide Pisani and many others

08.01.2026 07:39 — 👍 67    🔁 25    💬 1    📌 2
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How did organs originated in the evolution of multicellularity? Despite their obvious importance, we still lack a theory of evolutionary organogenesis. Here's a @cp-trendsecolevo.bsky.social paper on how the placenta can offer answers @multicellgenome.bsky.social www.researchgate.net/profile/Oliv...

26.12.2025 11:28 — 👍 36    🔁 7    💬 0    📌 0

📝 Abstract deadline: Tuesday, Feb 3, 2026.
Let’s fill #SMBE2026 with #protistsonSky love!

01.01.2026 10:45 — 👍 4    🔁 1    💬 0    📌 0

The real drama of life happened "backstage" in the unicellular world. 🎭🧬 #protistsonSky
Our postdoc Vika Shabardina is co-organizing this symposium with Annia (@ankarn.bsky.social). Two brilliant minds leading the evocell way!
Plus, a talk by @vikramalva.bsky.social. 👇

01.01.2026 10:45 — 👍 17    🔁 5    💬 1    📌 0
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New preprint out! Using ~75k environmental OTUs + 77 fossil calibrations, we reconstructed a Proterozoic timeline of eukaryote evolution. Our results show crown eukaryotes were already diversifying >1.6 Ga, long before the first undisputed fossils (~1.05 Ga).
🔗 DOI: www.biorxiv.org/content/10.6...

15.12.2025 08:19 — 👍 110    🔁 54    💬 4    📌 4
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Are you very busy but still want to learn what Aphelids are and why they are important to understand the evolution of Fungi?
Then check out our “Quick guide” on Aphelids published in collaboration with @deemteam.bsky.social, Sergey and Guifré. #protistsonsky
doi.org/10.1016/j.cu...

15.12.2025 17:41 — 👍 72    🔁 27    💬 2    📌 1
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Endogenized polinton-like viruses in the dinoflagellate Oxyrrhis marina uncover novel PolB fusion Marine viruses are ubiquitous entities that impact the biology of a large fraction of prokaryotic and eukaryotic diversity. Dinoflagellates are heterotrophic, mixotrophic and photosynthetic eukaryotes...

🎄 Just published 🎉! Our ongoing genome sequencing of the basal dinoflagellate Oxyrrhis marina uncovered a new lineage of endogenized Polinton-like viruses, OmPLV. Notably, OmPLV encodes ... [cont]
#VirEvol #MicroSky #Mevosky #SymbioSky #ProtistsOnSky

23.12.2025 16:39 — 👍 29    🔁 11    💬 1    📌 0

Very nice evidence of the power of convergence evolution in #terrestrialization. Congrats to all authors! @martaalvarez.bsky.social Jordi, Davide, @phil-donoghue.bsky.social & Jialin #metazoans

13.11.2025 18:56 — 👍 5    🔁 0    💬 0    📌 0

Indeed! Very nice collaboration with @irenedelrey.bsky.social @sebasn1.bsky.social @konsmitsi.bsky.social @jtrinidad13.bsky.social Montse Elias, Padhu & others to decipher the origin of the #plasmalogen biosynthesis pathway. @ibe-barcelona.bsky.social @icreacommunity.bsky.social @csic.es

12.11.2025 19:05 — 👍 13    🔁 2    💬 0    📌 0

thanks for your contribution, Will! Sad you are not here but happy you can be at home!

11.10.2025 05:33 — 👍 1    🔁 0    💬 0    📌 0
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And for the online participants we had the first round of Backstage Interviews led by Vika interviewing Iñaki Ruiz-Trillo and Laura Nuño de la Rosa. #Multicellverse @multicellgenome.bsky.social

09.10.2025 16:58 — 👍 3    🔁 1    💬 0    📌 0

@multicellgenome.bsky.social @philipcball.bsky.social @ucciuv.bsky.social @sfelena.bsky.social @pablocarb.bsky.social @ccbiologiquesuv.bsky.social @sesbe-org.bsky.social @tonigabaldon.bsky.social @paucarazo.bsky.social
Thanks @pacoalanaranja.es for the pic that captures the mood of the discussions

01.10.2025 16:45 — 👍 9    🔁 4    💬 1    📌 0
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📣The #EMBOWorkshop hosted by @multicellgenome.bsky.social Lab has begun!

🔬Three days filled with talks from international experts exploring the #evolution and origins of #multicellularity🦠🧬

#Multicellverse #UnravellingEvolution #DiscoveringLife

09.10.2025 08:49 — 👍 7    🔁 3    💬 0    📌 0

gràcies!!!

30.09.2025 07:32 — 👍 1    🔁 0    💬 0    📌 0

Thrilled to see choanoflagellates can glide! I think this provide further support to the stunning complexity of the unicellular ancestor of animals, as we have been proposing. Congrats @thibautbrunet.bsky.social ! very nice work. #AnimalOrigins #choanos #multicellularity #protistsOnSky

12.09.2025 10:52 — 👍 12    🔁 1    💬 1    📌 0

cool!

12.09.2025 10:47 — 👍 1    🔁 0    💬 0    📌 0

Less than a month away! 📣 Our lab is so excited to co-host the #EMBOWorkshop on the evolution of #multicellularity.
Get ready to dive deep into the origins of multicellular life across all kingdoms. 🔬See you in Barcelona (or online) soon!

@prbb.org @csic.es

10.09.2025 09:46 — 👍 17    🔁 6    💬 0    📌 0

#PhDposition! Great PI, nice project, wonderful environment.
@IBE_Barcelona #microbes #evolution

10.09.2025 09:36 — 👍 1    🔁 1    💬 0    📌 0

No! This is not one of the Magnificent8! But also pretty interesting one! 🙂

10.09.2025 06:58 — 👍 1    🔁 0    💬 0    📌 0

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