@gjbrainresearch.bsky.social
The Geoffrey Jefferson Brain Research Centre combines discovery science and experimental medicine to rapidly translate research into healthcare benefit. Our research focuses on brain tumours, stroke and dementia, Parkinson's disease and rehabilitation.
🧠 Thanks for joining us this #WorldStrokeDay!
From research breakthroughs to patient involvement, and clinical trials, we’ve shared how we’re shaping the future of stroke care.
📖 Read the full roundup here:
linkedin.com/posts/geoffr...
#StrokeResearch #GJBRC #StrokeCare
🪥Can better oral health reduce pneumonia risk after stroke?The CHOSEN trial tested enhanced oral care in stroke patients with dysphagia across 4 NW stroke units.
✅ 91% adherence
✅ Safe & feasible
🧑⚕️ Lays groundwork for a full-scale trial
www.ahajournals.org/doi/10.1161/...
🧠 A new clotbuster drug-caADAMTS13-shows promise for treating platelet-rich brain clots in stroke.
🧪 In mice, it outperformed therapies like rtPA & TNK.
👏 Developed by @manchester.ac.uk researchers & funded by
@thebhf.bsky.social & @uomif.bsky.social
📄 shorturl.at/piVBQ
Cognitive problems after stroke are common—but full assessments take too long
🕒 StrokeCog-15: a 15-min test battery validated in 2 stroke cohorts, outperforming longer tools
👏Developed by Stroke IMPaCT researchers and funded by
Fondation Leducq
#WorldStrokeDay
🔗https://shorturl.at/f6hb0
🚑Diagnosing Stroke in the Ambulance
The DIAGNOSIS study aims to detect brain bleeds before hospital arrival.
Combining clinical signs with GFAP testing could transform early stroke care.
🙋 PCPIE members shared views on data use & meaningful outcomes.
🔗https://t.co/zBhgMHlT9j
🧠Saving Lives with the ABC Care Bundle
Intracerebral haemorrhage = 1 in 10 strokes, high mortality.
Prof Parry-Jones's ABC Care Bundle saves 2–3 lives/month.
@ncaresearchnhs.bsky.social
🧑🤝🧑 PCPIE group informed future research directions.
#StrokeInnovation #ICH #PCPIE
Swallowing & Brain Stimulation
Post-stroke dysphagia affects up to 65% of survivors.
Dr Ayodele Sasegbon is exploring cerebellar rTMS to improve swallowing.
📃 PCPIE members were invited to help refine the study protocol & outcome measures.
#StrokeCare #Dysphagia #PCPIE
🧠 Vision Problems After Stroke
Stroke survivors often face visual field loss - affecting 1 in 5.
Dr Claire Howard @nihr.bsky.social funded study uses virtual reality to improve recovery.
🧑🤝🧑PCPIE members are shaping the intervention to reflect what matters most.
#StrokeRecovery
PCPIE is central to research at the Geoffrey Jefferson Brain Research Centre.
💬 Our Stroke Group - made up of stroke survivors & those with lived experience - helps shape studies that matter most.
#WorldStrokeDay
Our new research is helping us better understand a type of brain vessel disease that can lead to stroke and dementia.
🔬 Faulty COL4A1 gene = bleeding & vessel damage. Blocking MMP9 = reduced harm.
#StrokeResearch
@dns-uom.bsky.social
sciencedirect.com/science/arti...
29.10.2025 13:29 — 👍 0 🔁 0 💬 1 📌 0
🧠 Every five minutes, someone in the UK suffers a stroke.
🔬 Our researchers are working across discovery science, experimental medicine, and clinical care to change that.
👉 Read on to see how their work is shaping the future of stroke prevention, treatment and recovery.
#WorldStrokeDay
🎉Dr Yolanda Ohene is a finalist for the EDI Award at the @womeninneurouk.bsky.social Awards 2025! Nominated by her colleagues for her inclusive research culture. Good luck in November🌟
🔗http://bit.ly/3WVE1NA
🧠 The latest Prevent the Preventable podcast from The Natalie Kate Moss Trust features Olivia Murray from our imaging theme, exploring how AI and imaging are transforming recovery predictions for brain haemorrhage patients.
🎙️ www.youtube.com/watch?v=BA5q...
🧠New from our brain tumour theme in Neurosurgery.
Insights into surgery after bevacizumab (a tumour-slowing drug) in NF2-related vestibular schwannoma. Study highlights how timing & dosage can help reduce bleeding risks and guide safer treatment planning
shorturl.at/E9c92
#NeuroOncology #research
Prof Adrian Parry-Jones
ICYMI: Hear Prof Adrian Parry-Jones (Northern Care Alliance, @fbmh-uom.bsky.social & @gjbrainresearch.bsky.social) talking about important #stroke research, esp #ICH, in GM on Radio Manchester - it starts at 12.31
www.bbc.co.uk/sounds/play/...
🧠 Tune in this morning to BBC Radio Manchester to hear Prof Adrian Parry Jones from our #stroke theme talk with Mike Sweeney about our work to improve diagnosis and care.
🔊 Listen live: bbc.co.uk/sounds/play/...
@ncaresearchnhs.bsky.social
🚨 We're hiring! Join Prof Petra Hamerlik’s Brain Tumour Biology Lab as a Research Assistant - supporting cutting-edge multi-omics work on brain tumours.
#CancerResearch #ManchesterJobs
@uom-dcs.bsky.social
👉https://www.jobs.manchester.ac.uk/Job/JobDetail?isPreview=Yes&jobid=33559&advert=external
More PhD opportunities across brain inflammation, Parkinson’s, imaging, nanotech, and neurodevelopment
📣 Please share widely and tag anyone who might be interested in joining our research community!
@fbmh-uom.bsky.social @dns-uom.bsky.social @uom-dcs.bsky.social
www.linkedin.com/posts/geoffr...
🎓 Exciting PhD Opportunities in Stroke, Dementia & Brain Health! 🧠
We’re thrilled to announce a wave of new Medical Research Council (MRC) Doctoral Training Partnership (DTP) - funded PhD studentships at the Geoffrey Jefferson Brain Research Centre...
www.linkedin.com/posts/geoffr...
🎉Good news Friday!🎉
Dr Daniel Lewis has been awarded funding from
Cancer Research Horizons part of @cancerresearchuk.org
to help turn advanced imaging software into a clinical tool for brain tumour care.
Early steps in transforming DCE-MRI analysis for real-world impact 👇
🔗 shorturl.at/sj0RO
🧠Exciting news! Further funding for pioneering approach to slow or stop Parkinson’s...
Dr Roy Ng, our preclinical dementia lead joins @parkinsons.org.uk funded project with Cellestial Health to explore astrocyte-targeted therapies for Parkinson’s.
👉https://shorturl.at/O28cN
Professor Petra Hamerlik with study participant Alex and his wife Emma.
Prof Petra Hamerlik, part of our Brain Tumour theme, is leading research funded by #StandUpToCancer (from @cancerresearchuk.org & @channel4.bsky.social) exploring how tear fluid could offer early warning signs of brain tumours.
A simple eye test could be a game-changer. 🧪
🔗 shorturl.at/KQxK5
Join the Dyer Lab (Dr @douglaspdyer.bsky.social) as a Research Associate in Neuro-Immunology & Extracellular Matrix Biology (ImmunoMatrix).
🔬 Focus: chemokines, glycocalyx & inflammatory disease
📍 Cutting-edge biochem, biophysics & in vivo biology
Apply now 👉 shorturl.at/jEQ6G
From a 2015 pilot at Salford Royal Hospital to a nationwide NHS rollout in 2025 - the ABC Bundle led by @adrianpj1 is transforming stroke care, cutting deaths by 30% within a month after brain haemorrhage.
#KnowYourNumbers Week.
🔗 www.nataliekatemoss.co.uk/blog/researc...
📖 Read Prof Greenstein’s editorial here: shorturl.at/2JAAa
🔗 About Microvascular @ Manchester:
microvascularmanchester.com
This #KnowYourNumbers Week, don’t forget to check your blood pressure. 💙
💡 A recent publication in the Journal of Hypertension shows how controlling BP can protect brain health + prevent cognitive decline.
It builds on findings from the SPRINT-MIND study which found keeping systolic BP <130 mmHg reduced risk of mild cognitive impairment + dementia.
Led by Prof Adam Greenstein (@manchester.ac.uk @mft-edi.bsky.social) and @harry-pritchard.bsky.social the group is one of the world’s largest teams dedicated to small artery research.
They’re exploring how hypertension damages the brain’s blood vessels, raising risk of #vasculardementia + #stroke.
🧠 High blood pressure doesn’t just affect your heart – it can also drive dementia + stroke.
During #KnowYourNumbers Week, researchers in the Microvascular @ Manchester group are uncovering how. 👇
Today we’re celebrating two Professorial Inaugural Lectures at @manchester.ac.uk
Congratulations to Prof Catherine Lawrence and Prof Matt Hepworth from our stroke and dementia and inflammation themes.
🔗https://shorturl.at/sVZw5/
