@pennmemorycenter.bsky.social
A Penn Medicine organization evaluating, diagnosing and researching Alzheimer's disease and related diseases.
The FDA recently approved a safer way to give donanemab, a treatment that targets amyloid in the brain. This new approach lowers the risk of serious side effects, especially for people with a genetic risk factor called APOE4.
Learn more: bit.ly/3Hkk6ni
In the Season 3 finale of The Age of Aging, Dr. Jason Karlawish, co-director of the Penn Memory Center, highlights the urgent need to better diagnose and understand Lewy Body Dementia (LBD).
🎙️ Full episode: bit.ly/4eY8L8K
Day 4 at #AAIC25 is packed with Penn-led insights on improving memory care, advancing AI in neuroimaging, and shaping inclusive research protocols.
Here’s what our team is sharing today:
Swipe through the full lineup. #PennatAAIC25
Day 3 at #AAIC25 shows how every piece of the puzzle matters, from students to established clinicians.
Katrina Bazemore breaks down how gene-variant strategies impact Alzheimer’s risk scores.
Dr. Sandhitsu Das explores how ARIA affects brain changes during anti-amyloid treatment. #PennatAAIC25
Congratulations to Dr. Christos Davatzikos, recipient of the 2025 de Leon Prize in Neuroimaging at #AAIC25!
One of 10 researchers honored for his work in Alzheimer’s science, he was recognized for a top paper in neuroimaging of neurodegenerative disease.
🔗 bit.ly/472qKZK
#PennatAAIC25
It’s day 2 of #AAIC25 and Penn researchers are leading conversations around biomarkers, brain imaging, digital tools, and data systems shaping the future of care and prevention.
#PennatAAIC25
AAIC 2025 officially kicks off today, and Penn is showing up in full force.
From biomarkers to global collaboration, our researchers are shaping the future of Alzheimer’s care.
👉 Follow #PennatAAIC25 for updates all week from Toronto.
AAIC 2025 is almost here and Penn is already on the ground!
Today marks the pre-conference day of the Alzheimer’s Association International Conference, with many of our researchers sharing their latest findings. Follow along all week at #PennatAAIC25 as Penn experts present their work in Toronto.
“I tried to be strong. I thought I could do it alone. I broke.”
In the season finale of the Age of Aging, caregiver Linda Szypula reflects on the emotional toll of caring for a loved one with Lewy Body Dementia, and the power of letting others in.
🎧 Listen now: bit.ly/4eY8L8K
All adults with Down syndrome develop Alzheimer’s pathology by age 40, yet were long excluded from trials.
Dr. Michael Rafii is changing that, building a pipeline of inclusive research from biomarkers to global studies.
Learn more about his work: bit.ly/46pljnv
Lewy Body Disease is the second most common cause of dementia, yet it’s often misdiagnosed and misunderstood.
In our Season 3 finale, we spotlight this complex condition through film, caregiving stories, and expert insights from Penn Memory Center Co-Director Dr. Jason Karlawish.
🎧 bit.ly/4eY8L8K
“He wasn’t a burden to me. But I shouldn’t have had to fight so hard for someone I loved. That was the burden.”
Mary’s brother Pete had Down syndrome. When he was diagnosed with Alzheimer’s, she became his care partner and advocate.
Read the full story, part of our Disability and Dementia Series
What happens to intimacy when dementia enters a relationship?
In the latest Age of Aging episode, Penn Memory Center Director of Social Work Alison Lynn opens up a quiet but common part of caregiving—and gives families permission to talk about it.
🎧 Listen now: bit.ly/3IlJ1Hb
“She went home to live with her family for another 10 years after it looked like she wasn’t going to live another day.”
When medications failed, Dr. Brent Forester turned to electroconvulsive therapy for an Alzheimer’s patient with severe aggression. What happened next sparked a new clinical study.
In our latest episode, caregiver and author Lisa Marshall shares the deeply personal story of loving—and letting go of—physical intimacy with her husband, Peter, after his Alzheimer’s diagnosis.
🎧 Listen now → bit.ly/3IlJ1Hb
📘 Explore Lisa’s memoir Oh Hello Alzheimer's → bit.ly/4kDMMFC
Stay connected with Penn Memory Center!
Whether you're looking for research updates, caregiver tips, or event announcements, we're just a follow away.
📍Find us on Instagram, Facebook, YouTube, LinkedIn, and Bluesky!
💬 “I felt like his wife again—not his caregiver.”
In our most vulnerable episode yet, caregiver and author Lisa Marshall opens up about love, grief, and the moment she chose to say goodbye to physical intimacy—with tenderness and intention.
Listen now: bit.ly/3IlJ1Hb
Learn more about the project by Dr. Kyra O'Brien and her team on a Warning Assessment and Alerting Tool for Cogntive Health (WATCH), one of our Year 4 awardees, here:
youtu.be/sy77pszD2g0?...
“We need to move in the direction of oncology. Early detection matters.”
Dr. Kyra O’Brien joined The Age of Aging to talk anti-amyloid therapies, new blood tests for Alzheimer’s, and why the GUIDE program could transform care for both patients and caregivers.
🎧 Listen now: bit.ly/408tb9d
After years of compassionate care, research, and mentorship at Penn Memory Center, Dr. Jeffrey Maneval is headed to MaineHealth to expand dementia care and research across rural Maine. His impact on patients, families, and future specialists will be long remembered.
03.07.2025 16:03 — 👍 0 🔁 0 💬 0 📌 0
Traveling this 4th of July with a loved one who has dementia? It can be done—with the right plan.
Penn Memory Center Director of Social Work Alison Lynn offers guidance for caregivers on managing expectations, staying flexible, and putting support systems in place.
As Chief Medical Officer at Penn Medicine, Dr. PJ Brennan helped lead the health system through the COVID-19 crisis.
In our latest episode, he reflects on what the pandemic revealed about how we care for older adults—and where we go from here.
🎧 Listen to the full episode: bit.ly/408tb9d
Bipolar disorder in older adults is more complex than many realize—and closely tied to dementia, depression, and aging.
Dr. Brent Forester, a leader in geriatric psychiatry, is uncovering why bipolar disorder may raise the risk for Alzheimer’s and related dementias.
Bipolar disorder in older adults is more complex than many realize—and closely tied to dementia, depression, and aging.
Dr. Brent Forester, a leader in geriatric psychiatry, is uncovering why bipolar disorder may raise the risk for Alzheimer’s and related dementias.
Formal help + family caregiving = better outcomes.
Economist Norma Coe lived it and studied it—finding that combining both led to better mobility, less depression, and higher self-rated health.
Read about her journey and research 👇
💡In this month’s Research Roundup, Postdoctoral Fellow Rory Boyle PhD outlines ways that researchers can study resistance and resilience to Alzheimer’s disease in people with Down syndrome.
Read now at the link in our bio or by visiting our website!
The Healthcare system is changing. Will dementia care keep up?
Dr. PJ Brennan and Dr. Kyra O’Brien talk dementia care, anti-amyloid therapies, and what the new GUIDE program means for patients and caregivers.
🎧 Tune in here: bit.ly/408tb9d
If you missed Dr. Walter Curioso's presentation on "AI for Strengthening Healthcare Systems in Low- and Middle-income Countries: A Perspective from Peru" you can watch the recording on our YouTube channel here:
youtu.be/PkfK3Ffvvpg?...
“The story started with love.”
After early-onset dementia changed their families, Diana Cose and Patty LaFleur built Lorenzo's House—a lifeline for young caregivers.
From peer matches to youth support groups, they’re reshaping dementia care.
🎧 Listen now: bit.ly/3Zr2VGC
At 8, Sierra’s dad was diagnosed with dementia.
At 16, she’s stepping into caregiving—and advocacy.
In the latest Age of Aging episode, Sierra shares what it’s like to grow up while helping a parent forget less and live more.
🎧 Hear her story on the latest Age of Aging episode: bit.ly/3Zr2VGC
