Dr. Dale Bredesen

People with more protein in their urine had a significantly greater risk of developing dementia, according to new research. Why? The same blood vessel damage that causes high-protein urine is likely harming the brain. https://beingpatient.com/urine-test-dementia-risk/

How Epstein-Barr is linked to Multiple Sclerosis has been a mystery. New research suggests that cross-reactive T cells targeting the brain protein Anoctamin-2 (ANO2) may be the culprit. https://www.clinicallab.com/new-mechanism-links-epstein-barr-virus-to-multiple-sclerosis-28526

A common bacterium that causes pneumonia and sinus infections can linger in the eye and brain for years, creating inflammation and possibly causing Alzheimer's, according to a new study. https://www.newswise.com/articles/common-bacteria-discovered-in-the-eye-linked-to-cognitive-decline

The benefits of weight loss medications may be shorter-lived than originally hoped. Those who stop taking GLP-1s may return to pre-treatment levels of body weight and heart disease risk within two years. https://sciencedaily.com/releases/2026/01/260128075359.htm

Those consuming more preservatives were more likely to develop several cancers and type 2 diabetes. The most significant link was between sodium nitrate, commonly used in cured meats, and prostate cancer. https://www.foodandwine.com/food-preservatives-linked-to-cancer-diabetes-new-study-11890398

As you might well imagine, the brains of those getting around 150 minutes of weekly moderate-to-vigorous exercise appeared biologically younger in MRI scans in new research. https://www.sciencealert.com/exercise-can-actually-make-your-brain-look-younger-mri-scans-reveal

Obesity and high blood pressure can directly cause dementia, not just increase the risk, according to new research. Higher body weight, particularly when it led to elevated blood pressure, actually harmed brain health. https://sciencedaily.com/releases/2026/01/260126231847.htm

Alzheimer's disease blood biomarkers rose much more quickly in obese individuals, showing obesity is a modifiable risk, according to research from our colleague Cyrus Raji. https://sciencedaily.com/releases/2025/12/251210092019.htm

The Randomized Control Trial isn’t just the most successful Alzheimer’s trial ever, it’s a building block for even more future success. Read more about what’s ahead in my new blog for Apollo Health.

https://www.apollohealthco.com/archimedes-alzheimer-and-trials-a-place-to-stand/

Even after years of warnings, millions with dementia are still prescribed drugs linked to falls and confusion. Do not wait for the medical establishment to catch up to the science—take steps now to prevent and reverse cognitive decline. https://sciencedaily.com/releases/2026/01/260113220915.htm

On January 23rd at 2pm PT, Dr. Craig Tanio, one of the key trial investigators, will describe enhancements to the ReCODE protocol.

To register for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_-ROlIql_QtqcawMw_bIEhw#/registration

Arginine can help reduce the risk of tooth decay, shifts the oral microbiome, and reduces acid formation in the mouth. Given the mouth-brain connection, could an arginine oral rinse be neuroprotective? https://scitechdaily.com/goodbye-cavities-this-natural-amino-acid-helps-teeth-fight-sugar/

This is an important chart from our recent preprint of the Evanthea trial, which was based on ReCODE.

You don’t need to accept the standard of care or settle for a reduced rate of decline - it is possible to reverse the symptoms of Alzheimer’s: https://www.apollohealthco.com/evanthea-trial/

The Evanthea randomized clinical trial has concluded, and the cognitive improvements exceed anything previously published. Join Dr. Bredesen on Friday, January 9th at 2 PM PT to discuss: https://us02web.zoom.us/webinar/register/WN_dMG3GyFlSLigtQoSanuUQA#/registration

Your body’s natural cleaning crew, mononuclear phagocytes, do less cleaning as they age. By developing “young” phagocytes using stem cells, researchers improved memory and created healthier microglia in mice. https://www.sciencealert.com/young-immune-cells-partly-reverse-alzheimers-symptoms-in-mice

Happy New Year to all, and I hope that everyone is enjoying time with loved ones. Meanwhile, we have very exciting results from our randomized controlled trial, and these have just been posted as a preprint: https://www.preprints.org/frontend/manuscript/8118568f183e2ba91ec2a1d3b3d08fb9/download_pub

Breakthroughs in medical research are addressing 4 of the world's most serious health problems: Alzheimer's, cancer, pandemics, & antibiotic resistance. Learn about advances provided by 21st-Century medicine in my new blog. https://www.apollohealthco.com/solving-four-of-the-worlds-health-problems/

Free radicals generated in non-neuronal brain cells promote dementia, according to researchers. Their study suggests that blocking this activity can protect the brain. https://news.weill.cornell.edu/news/2025/11/study-pinpoints-source-of-free-radicals-in-the-brain-that-may-fuel-dementia

A longitudinal study found that those with moderate to severe obstructive sleep apnea were far more likely to have visible cerebral microbleeds on MRIs. Identifying yet another way that sleep apnea could contribute to cognitive decline. https://www.medpagetoday.com/pulmonology/sleepdisorders/118302

Those brief bouts of attention wandering may actually be moments of brain maintenance! Attentional failures, particularly after sleep deprivation, could be the result of your brain working to remove waste. https://www.sciencealert.com/zoning-out-may-be-your-brains-rinse-cycle-study-finds

In an observational study, teens who took the antibiotic doxycycline, which is a common prescription for acne, had a reduced risk of developing schizophrenia. https://www.sciencealert.com/common-acne-medication-linked-with-30-lower-schizophrenia-risk

Tooth infections can lead to bacteria in the bloodstream, inflammation, and impaired blood sugar control. But root canals can lower blood sugar levels. https://www.theguardian.com/science/2025/nov/18/root-canal-treatment-could-significantly-lower-blood-sugar-levels-study-suggests

Neuronic is finalizing a study on light therapy. We should wait for the final results, but it's good to see improvements in sleep, quality-of-life, hand-eye coordination, recognition, & auditory perception. https://www.neuronic.online/blog/can-light-therapy-help-with-memory-what-our-study-revealed

An analysis of studies found that nitrous oxide can provide rapid improvements and also sustained benefits after repeat treatments for those with depression, especially for those who haven't responded to other treatments. https://sciencedaily.com/releases/2025/12/251202052213.htm

Clearing beta-amyloid plaques does not repair key brain functions, according to new research on the drug lecanemab. The researchers are, unfortunately, just catching up to what we’ve all known. http://sciencealert.com/one-of-our-biggest-hopes-for-alzheimers-treatment-doesnt-seem-to-work

A research team “rebalanced the activity” of a specific set of overactive neurons in the amygdala of mice and found that they reversed the symptoms of anxiety. https://www.sciencedaily.com/releases/2025/11/251104013004.htm

Walnuts, which are high in omega-3 fatty acids, polyphenols, flavonoids, and antioxidants, supported focus and memory and improved cognitive function in a new study. For max benefit, consume raw to protect the omega-3 fatty acids. https://foodandwine.com/walnuts-breakfast-brain-health-study-11840393

Frequent consumption of ultra-processed foods was associated with altered brain structure, and those differences could be part of a feedback loop promoting overeating, according to a study of 30,000 participants. https://sciencedaily.com/releases/2025/10/251020092824.htm

A new device is helping those with advanced age-related macular degeneration see again, and likely provides cognitive protection by supporting brain stimulation. https://www.nbcnews.com/health/health-news/tiny-eye-implant-special-glasses-legally-blind-patients-can-read-rcna238488

Live from Palm Springs at the California Assisted Living Association Conference! 🌴 Discussing how The Vineyards translates our research into real-life programs for their residents. Learn more about our partnership here: https://lifeatthevineyards.org/cognitive-care