The Lancet Regional Health - Western Pacific

New issue is live!🙌

Read our series about child & adolescent #MentalHealth in the #WesternPacific, public misuse of #Antibiotics in #China, epidemiology of young adults with #HeartFailure & more!

🖋️ Editorial: #BloodPressure control in Asia
🎨 Cover by Zidi Wu
🔗 tinyurl.com/mt8578w7

Cover picture. Image by Dr Diego Pitta.

Our joint series with @thelancethaem.bsky.social on Mature T-/NK-Cell #Lymphoma is online.

🔗 Epidemiology: East & West tinyurl.com/ytmywjr4
🔗 Update on molecular characterization & tumor microenvironment tinyurl.com/tvfzchb6
🔗 Emerging treatments tinyurl.com/bdesbfnv

🎨 Image by Dr Diego Pitta.

Insulin resistance and the risk of incident depression: the role of age, glycemic status, and adiposity in a prospective cohort study Insulin resistance may be a modifiable risk factor for depression, underscoring the importance of early screening and management of insulin resistance to potentially reduce the burden of depression, e...

🆕 #InsulinResistance may be a modifiable risk factor for #depression, underscoring the importance of early #screening and management to potentially reduce the burden of depression, especially among at-risk subgroups.

#MedSky #EndoSky
🔗 Full text: tinyurl.com/5b69328x

August issue is live!🙌

Read our series about #Cancer in #FirstNations Australians, #tuberculosis development in #China and #Vietnam, #AMR partnership by #Bhutan and #Philippines & more!

🖋️Editorial: Our first 5 years: advancing the health and wellbeing in the #WesternPacific
🔗 tinyurl.com/mbukkhkt

Research in context (RIC) panel

🆕 Routine AI assistance may lead to loss of skills in health professionals who perform colonoscopies, study suggests in @lancetgastrohep.bsky.social.

Find out more 👉 bit.ly/4fFEyMo

Plots show Insulin Secretion-Sensitivity Index-2 (ISSI-2) hyperbolae relating insulin sensitivity (Matsuda index) and insulin secretion (AUCinsulin/AUCglucose) on oral glucose tolerance testing in individuals with and without remission of prediabetes at visit 1 (A) and visit 2 (B); red dots and blue dots indicate individual data points. In (C), corresponding sections of the four hyperbolae are superimposed for direct comparison; arrows indicate the changes in the median values of insulin sensitivity and insulin secretion (dots) between visit 1 and visit 2 in the remission and non-remission groups. ISSI-2=Insulin Secretion-Sensitivity Index-2.

Recovery of β-cell function is the dominant determinant of the remission of prediabetes, akin to its role in remission of diabetes but at an earlier point in the natural history of dysglycaemia www.thelancet.com/journals/lan...
#prediabetes #remission

#MedSky #EndoSky

Circulating tumour cells & ctDNA in patients with resectable colorectal liver #metastases: a prospective observational biomarker study

Postoperative ctDNA and CTC detection are strong, independent predictors for a shorter RFS after local treatment

www.thelancet.com/journals/ecl...
#OncoSky #MedSky

The psychological impact of conflict in the Middle East from 2023 to 2025 on Australian communities: a prospective cohort study This is a unique study of women’s mental health in a multicultural, high-income country, undertaken during conflict occurring in another region of the world. Panic Disorder symptoms, poorer quality of...

🆕 #MentalHealth risks are faced by populations in high-income countries during a #war in their country of origin.

New study in #Australia shows #PanicDisorder, poor quality of life & psychosocial #stress increased in women connected by #migration to conflict-affected regions.

🔗Full text #MedSky

July issue is live!🙌

Read contributions of #CVD risk factors in #Japan, #Antimicrobial stewardship interventions in #Vietnam, associations of #STI and #pregnancy outcomes in #Australia & more!

🖋️Editorial: Equitable, safe and reliable #BloodSupply in #WesternPacific
🔗 tinyurl.com/5xb2u7xk

Myopia and high myopia trends in Chinese children and adolescents over 25 years: a nationwide study with projections to 2050 Despite stabilization in overall myopia prevalence, the continued rise in high myopia underscores the need for targeted control measures. Projections emphasize the importance of addressing regional di...

🆕 Global rise in #myopia particularly in #Asia presents public health challenges.

In #China, overall myopia prevalence is stabilized but not for #HighMyopia, which is expected to rise to 22.1% by 2050. Targeted control for #adolescents are urgently needed.

🔊 Listen to Podcast tinyurl.com/ymnr3cd9

Our August issue is out now at www.thelancet.com/gastrohep!

Content includes Crohn’s disease, MASLD, faecal incontinence, variceal bleeding, food allergies, and more…

#GastroSky #LiverSky #MedSky #IBDSky

Are you ready for your research to spark global conversation? ✨ Begin your publication journey with us today and help to advance health and science worldwide.

🔗 hubs.li/Q03vpxN70

Congratulations to our authors and peer reviewers, whose expertise and hard work enable us to publish high-quality, evidence-based research focused on the Western Pacific. This is as much your achievement!

We are a world-leading clinical and health services journal dedicated to the Western Pacific. While a partial measurement of our impact, we are pleased to share our Impact Factor of 8·1 and CiteScore of 11·4.

🔗 hubs.li/Q03vfn5J0

Recording during the podcast preparation process.

#Biologics is commonly used in #rheumatology but inequitable access exists in the #AsiaPacifc & #LMICs.

Our joint podcast with @thelancetrheum.bsky.social with Prof Xue Li discusses the factors that delay access in Asia, any #policy changes & role of #biosimilars.

🔊Listen now: tinyurl.com/ys5x7uxn

Read our July Issue, featuring thyroid eye disease, type 2 diabetes remission, IcoSema, adrenal incidentalomas, CGM, gestational diabetes, congenital hypogonadotropic hypogonadism, junk food and soda taxes, childhood obesity, Prader-Willi syndrome, and more bit.ly/2LArJXX

#MedSky #EndoSky #OncSky

🚨Our July issue is now live: thelancet.com/issue/S1470-...

Explore articles on #gastrointestinalcancer, #prostatecancer, #WHO essential medicines, #NSCLC, #breastcancer, and cancer genomics

First Nations Cancer Series cover picture. Copyright: Mayall/ullstein bild via Getty Images

🆕 Check out new series: #Cancer in First Nations Australians.

4 papers in the series highlight the needs of #children with cancer, education insights, #genetic factors on cancer risk & cancer #research in #FirstNations Australians.

🔗 tinyurl.com/uw8j5zc4
#OncSky #Aboriginal #TorresStraitIslander

June issue is live!🙌

Read #AI model to detect #CognitiveImpairment in Japan, #ChildhoodAdversity and #perinatal mental health, #tick-borne diseases in China & more!

🖋️Editorial: Delayed #endometriosis diagnosis in #AsiaPacific

🎨Cover: Xiaolin Xu, a painting with real leaf
🔗 tinyurl.com/4m7445jb

A scoping review of health research in four Pacific Island countries and areas (Cook Islands, Fiji, Guam and Tonga) from 2014 to 2024 Health research capacity remains constrained in Pacific Island Countries. This scoping review examined health research output in the Cook Islands, Fiji, Guam, and Tonga from 2014 to 2024 following the...

Health research capacity is constrained in #PacificIslandCountries.

A scoping review in the #CookIslands, #Fiji, #Guam & #Tonga shows insufficient solution-focused studies and few studies had local authors - Calls for a greater local ownership, domestic #funding & ethical oversight.

🔗Full text

Effect of aspirin on small for gestational age neonates in pregnancies at high-risk for preeclampsia: a secondary analysis of a cluster randomised clinical trial Aspirin prophylaxis appears to be associated with a reduction in the rate of early-SGA and a simultaneous increase in the rate of late-SGA neonates born at or after 32 weeks. These findings underscore...

Small for gestational age #SGA neonates are at higher risk for adverse #perinatal outcomes.

An analysis of #FORECAST trial shows #aspirin prophylaxis was associated with reduced rate of early-SGA and increased rate of late-SGA neonates born >= 32 weeks 🧑‍🍼

🔗Full text #MedSky #ObGynSky #ReproSky

Hyperuricemia, gout and the associated comorbidities in China: findings from a prospective study of 0.5 million adults In Chinese adults, gout was associated with several comorbidities and a poor health trajectory. Our findings reinforce the need for prevention and management of gout and associated comorbidities.

🆕A study covering 0.5 million adults from #China Kadoorie Biobank #CKB led by Dr Pek Kei Im et al. from Oxford and Peking University has found that #gout, the most common form of inflammatory arthritis, is linked to increased risks of several diseases.
#Comorbidity #MedSky @beckyim.bsky.social

New #geospatialmaps from The Kids & @curtinmedia.bsky.social ‪reveal Western Pacific hotspots for #parasiticworms. Soil-transmitted helminth infections like hookworm, roundworm & whipworm affect ~1.5B people globally but eradication efforts have stalled: shorturl.at/4v4og @lancetrh-wpac.bsky.social

Abstract of article named "Lessons for future outbreaks from successful contact tracing systems in Asia"

A new article compares the #ContactTracing systems of #Japan, #Thailand, #Singapore & #Vietnam 🌏

"We uncovered the key elements within these successful systems, namely Speed, Capture and Accuracy, designed specific for the countries’ settings."

🔗Full text: tinyurl.com/bda98cym
#IDSky #MedSky

A podcast interview with Dr Nickson and Dr Mann.

Do you know how risk-adjusted screening strategies can save lives?

Check out our latest #Podcast with Carolyn Nickson & Bruce Mann, who share their valuable insights on risk-adjusted #BreastCancer screening in #Australia and #WesternPacific.

🔊Link to audio: tinyurl.com/yysu3efs
#OncSky #MedSky

New issue is live!🙌

Featuring #BreastCancer prevention in #WesternPacific, adolescent #MentalHealth in #HongKong, persistent #LymphaticFilariasis in Tonga & more!

🖋️Editorial: Advancing #patient-centred care in clinical #trials

🎨Cover: Sandra Chan, Samara Hussain
🔗 tinyurl.com/28n57466

Evaluating the technical feasibility of serological testing and treatment for Plasmodium vivax in mobile at-risk of malaria Cambodian populations The participation rates and overall technical feasibility of PvSeroTAT in highly mobile individuals living within communities in malaria endemic areas of Cambodia were very promising. PvSeroTAT with a...

In #Cambodia, a new PvSeroTAT approach helps to target #Malaria elimination by 2025.

#Plasmodium vivax prevalence dropped in all villages including both intervention & control areas - Benefit is seen in shared forests as #Hypnozoites were eliminated from the common reservoir🦟

#IDSky #MedSky

Released yesterday in 𝗧𝗵𝗲 𝗟𝗮𝗻𝗰𝗲𝘁 𝗥𝗲𝗴𝗶𝗼𝗻𝗮𝗹 𝗛𝗲𝗮𝗹𝘁𝗵 – 𝗪𝗲𝘀𝘁𝗲𝗿𝗻 𝗣𝗮𝗰𝗶𝗳𝗶𝗰 - 𝘜𝘯𝘥𝘦𝘳𝘦𝘴𝘵𝘪𝘮𝘢𝘵𝘪𝘯𝘨 𝘩𝘦𝘢𝘵-𝘳𝘦𝘭𝘢𝘵𝘦𝘥 𝘮𝘰𝘳𝘵𝘢𝘭𝘪𝘵𝘺—𝘢 𝘤𝘰𝘮𝘱𝘢𝘳𝘪𝘴𝘰𝘯 𝘰𝘧 𝘦𝘹𝘤𝘦𝘴𝘴 𝘮𝘰𝘳𝘵𝘢𝘭𝘪𝘵𝘺 𝘢𝘯𝘥 𝘥𝘦𝘢𝘵𝘩 𝘳𝘦𝘤𝘰𝘳𝘥 𝘴𝘵𝘶𝘥𝘪𝘦𝘴 𝘧𝘰𝘳 𝘈𝘶𝘴𝘵𝘳𝘢𝘭𝘪𝘢

Peer-reviewed correspondence article (open-access) via: www.thelancet.com/journals/lan...
@lancetrh-wpac.bsky.social

Post-pandemic excess mortality of COVID-19 in Hong Kong: a retrospective study Our findings highlight the lasting mortality impact of pandemic among vulnerable populations, specifically the older population, possibly due to the post-COVID conditions and circulating COVID-19, sug...

🆕 Is there a lasting impact of #COVID in the post-pandemic era?

Latest cohort study in #HongKong shows persistent post-pandemic excess #mortality in vulnerable groups vs. pre- #Omicron period. #Old adults are affected, whilst the #young have near-zero excess mortality🦠

🔗 Full text #IDSky #MedSky

Progress towards the UNAIDS 2030 HIV prevention target in New South Wales, Australia: a population-based study HIV notifications in GBM in NSW have dropped by more than half since 2010. In inner Sydney areas with a high prevalence of gay men, prevention uptake was highest, and the decline in notifications appr...

🆕 #HIV among gay, bisexual & men having sex with men #GBM dropped by >half since 2010. Inner #Sydney has the highest #prevention uptake and 90% decline in HIV notifications.

If prevention extended population-wide, #Australia can reach UNAIDS ending #AIDS target by 2030 🩺

#MedSky #HIVSky #IDSky