The Lancet Regional Health - Western Pacific

#LowBirthRate in Asia Pacific consists of complex drivers. Check out our two #podcasts with experts in #fertility!

🎧 Listen to Cuilin and Jean about both the biological and social determinants of fertility tinyurl.com/yzkk84f4

🎧 Listen to David and Lee about male #infertility tinyurl.com/548ae2p8

#LowBirthRate is a concern in the #WesternPacific, where countries begin to have total #fertility rates below 2.1 per woman.

Check out our series on #LowBirthRate discussing how #women’s and #men’s health & #socioeconomic factors shaped the change.

Link to the series 👉 lnkd.in/gaYkdpP7 #ObgynSky

Risk of dengue following prior SARS-CoV-2 infection: a population-based cohort study Increased risk of DENV-infection (primarily DENV3) was observed up to 300 days post-SARS-CoV-2 infection (predominantly Omicron). While not irrefutable proof for possible antibody-dependent enhancemen...

Risk of dengue following prior SARS-CoV-2 infection: a population-based cohort study - The Lancet Regional Health – Western Pacific www.thelancet.com/journals/lan...

New issue is live!🙌

Read about smoking & #vaping in #Oceania, pediatric #MASLD in #China, smartphone-based #CBT in #Japan, #Malaria microscopy in #Indonesia & more!

🖋️ Editorial: #Diabetes underdiagnosis
🎨 Cover by Van-Mai CAO-LORMEAU
🔗 tinyurl.com/4haau2s3

#MedSky #IDSky #PsySky

In #Australia, urban-rural #disparities exist in cancer health. Facility & staff shortage lead to late diagnosis, fewer options and poorer outcomes.

Check out our series about #Rural Cancer Health. #Cancer survivorship shouldn't depend on where you live.

🔗 tinyurl.com/pmr3rety #MedSky #OncSky

Tracking the course of vaping and cigarette smoking across adolescence: the Child to Adult Transition Study These patterns of vaping and smoking in young Australians affirm that regulations and public health initiatives are urgently needed to prevent uptake of all nicotine and tobacco products.

Recent study in #Australia shows that 47% of adolescents reported #vaping at any frequency at age 20.

In contrast to the belief that vaping is short-lived, almost half of these adolescents were vaping across consecutive years & more than one-third reported #escalating use.

🔗 Full text below

Mortality among transgender persons: a Taiwan matched-population and sibling-comparison cohort study In Taiwan, transgender persons had higher all-cause and suicide mortality than population controls; in within-family comparisons, the suicide mortality excess persisted, indicating influences beyond s...

#Transgender persons were reported to have excess #mortality in Western cohorts. A study in #Taiwan also identified increased risks of both #AllCause and #ExternalCause of deaths especially due to #suicides.

Time to prioritize targeted mental health & #equitable access to gender-affirming care.

Adverse health outcomes among migrant workers and transnational families in the Asia–Pacific: a systematic review and meta-analysis Migrant workers in the Asia–Pacific face substantial risks of a wide range of occupational injuries and illnesses. Although some studies support the “healthy migrant effect,” this advantage clearly di...

Labor migration is growing globally - #migrant workers are more likely to experience exploitative work.

A meta-analysis in #AsiaPacific region identified 88% of migrant workers had #occupational injuries, pesticide #poisoning symptoms & #respiratory diseases, and 75% worked in high-risk sectors.

Drug-resistant gram-negative bacterial infections in children in the Oceania region: review of the epidemiology, antimicrobial availability, treatment, clinical trial and pharmacokinetic data, and key... Gram-negative bacterial infections remain a major cause of morbidity and mortality in children and neonates globally, compounded by the rise of antimi…

Excited to publish this review with kidsdose.org.au network summarising the available clinical trial, pk data and evidence gaps in antibiotic tx for resistant Gram neg infections in kids. www.sciencedirect.com/science/arti.... #idsky #paedsid #pedsid @mcri.bsky.social @lancetrh-wpac.bsky.social

New issue is live!🙌

Read our series about child & adolescent #MentalHealth in the #WesternPacific, public misuse of #Antibiotics in #China, epidemiology of young adults with #HeartFailure & more!

🖋️ Editorial: #BloodPressure control in Asia
🎨 Cover by Zidi Wu
🔗 tinyurl.com/mt8578w7

Cover picture. Image by Dr Diego Pitta.

Our joint series with @thelancethaem.bsky.social on Mature T-/NK-Cell #Lymphoma is online.

🔗 Epidemiology: East & West tinyurl.com/ytmywjr4
🔗 Update on molecular characterization & tumor microenvironment tinyurl.com/tvfzchb6
🔗 Emerging treatments tinyurl.com/bdesbfnv

🎨 Image by Dr Diego Pitta.

Insulin resistance and the risk of incident depression: the role of age, glycemic status, and adiposity in a prospective cohort study Insulin resistance may be a modifiable risk factor for depression, underscoring the importance of early screening and management of insulin resistance to potentially reduce the burden of depression, e...

🆕 #InsulinResistance may be a modifiable risk factor for #depression, underscoring the importance of early #screening and management to potentially reduce the burden of depression, especially among at-risk subgroups.

#MedSky #EndoSky
🔗 Full text: tinyurl.com/5b69328x

August issue is live!🙌

Read our series about #Cancer in #FirstNations Australians, #tuberculosis development in #China and #Vietnam, #AMR partnership by #Bhutan and #Philippines & more!

🖋️Editorial: Our first 5 years: advancing the health and wellbeing in the #WesternPacific
🔗 tinyurl.com/mbukkhkt

Research in context (RIC) panel

🆕 Routine AI assistance may lead to loss of skills in health professionals who perform colonoscopies, study suggests in @lancetgastrohep.bsky.social.

Find out more 👉 bit.ly/4fFEyMo

Plots show Insulin Secretion-Sensitivity Index-2 (ISSI-2) hyperbolae relating insulin sensitivity (Matsuda index) and insulin secretion (AUCinsulin/AUCglucose) on oral glucose tolerance testing in individuals with and without remission of prediabetes at visit 1 (A) and visit 2 (B); red dots and blue dots indicate individual data points. In (C), corresponding sections of the four hyperbolae are superimposed for direct comparison; arrows indicate the changes in the median values of insulin sensitivity and insulin secretion (dots) between visit 1 and visit 2 in the remission and non-remission groups. ISSI-2=Insulin Secretion-Sensitivity Index-2.

Recovery of β-cell function is the dominant determinant of the remission of prediabetes, akin to its role in remission of diabetes but at an earlier point in the natural history of dysglycaemia www.thelancet.com/journals/lan...
#prediabetes #remission

#MedSky #EndoSky

Circulating tumour cells & ctDNA in patients with resectable colorectal liver #metastases: a prospective observational biomarker study

Postoperative ctDNA and CTC detection are strong, independent predictors for a shorter RFS after local treatment

www.thelancet.com/journals/ecl...
#OncoSky #MedSky

The psychological impact of conflict in the Middle East from 2023 to 2025 on Australian communities: a prospective cohort study This is a unique study of women’s mental health in a multicultural, high-income country, undertaken during conflict occurring in another region of the world. Panic Disorder symptoms, poorer quality of...

🆕 #MentalHealth risks are faced by populations in high-income countries during a #war in their country of origin.

New study in #Australia shows #PanicDisorder, poor quality of life & psychosocial #stress increased in women connected by #migration to conflict-affected regions.

🔗Full text #MedSky

July issue is live!🙌

Read contributions of #CVD risk factors in #Japan, #Antimicrobial stewardship interventions in #Vietnam, associations of #STI and #pregnancy outcomes in #Australia & more!

🖋️Editorial: Equitable, safe and reliable #BloodSupply in #WesternPacific
🔗 tinyurl.com/5xb2u7xk

Myopia and high myopia trends in Chinese children and adolescents over 25 years: a nationwide study with projections to 2050 Despite stabilization in overall myopia prevalence, the continued rise in high myopia underscores the need for targeted control measures. Projections emphasize the importance of addressing regional di...

🆕 Global rise in #myopia particularly in #Asia presents public health challenges.

In #China, overall myopia prevalence is stabilized but not for #HighMyopia, which is expected to rise to 22.1% by 2050. Targeted control for #adolescents are urgently needed.

🔊 Listen to Podcast tinyurl.com/ymnr3cd9

Our August issue is out now at www.thelancet.com/gastrohep!

Content includes Crohn’s disease, MASLD, faecal incontinence, variceal bleeding, food allergies, and more…

#GastroSky #LiverSky #MedSky #IBDSky

Are you ready for your research to spark global conversation? ✨ Begin your publication journey with us today and help to advance health and science worldwide.

🔗 hubs.li/Q03vpxN70

Congratulations to our authors and peer reviewers, whose expertise and hard work enable us to publish high-quality, evidence-based research focused on the Western Pacific. This is as much your achievement!

We are a world-leading clinical and health services journal dedicated to the Western Pacific. While a partial measurement of our impact, we are pleased to share our Impact Factor of 8·1 and CiteScore of 11·4.

🔗 hubs.li/Q03vfn5J0

Recording during the podcast preparation process.

#Biologics is commonly used in #rheumatology but inequitable access exists in the #AsiaPacifc & #LMICs.

Our joint podcast with @thelancetrheum.bsky.social with Prof Xue Li discusses the factors that delay access in Asia, any #policy changes & role of #biosimilars.

🔊Listen now: tinyurl.com/ys5x7uxn

Read our July Issue, featuring thyroid eye disease, type 2 diabetes remission, IcoSema, adrenal incidentalomas, CGM, gestational diabetes, congenital hypogonadotropic hypogonadism, junk food and soda taxes, childhood obesity, Prader-Willi syndrome, and more bit.ly/2LArJXX

#MedSky #EndoSky #OncSky

🚨Our July issue is now live: thelancet.com/issue/S1470-...

Explore articles on #gastrointestinalcancer, #prostatecancer, #WHO essential medicines, #NSCLC, #breastcancer, and cancer genomics

First Nations Cancer Series cover picture. Copyright: Mayall/ullstein bild via Getty Images

🆕 Check out new series: #Cancer in First Nations Australians.

4 papers in the series highlight the needs of #children with cancer, education insights, #genetic factors on cancer risk & cancer #research in #FirstNations Australians.

🔗 tinyurl.com/uw8j5zc4
#OncSky #Aboriginal #TorresStraitIslander

June issue is live!🙌

Read #AI model to detect #CognitiveImpairment in Japan, #ChildhoodAdversity and #perinatal mental health, #tick-borne diseases in China & more!

🖋️Editorial: Delayed #endometriosis diagnosis in #AsiaPacific

🎨Cover: Xiaolin Xu, a painting with real leaf
🔗 tinyurl.com/4m7445jb

A scoping review of health research in four Pacific Island countries and areas (Cook Islands, Fiji, Guam and Tonga) from 2014 to 2024 Health research capacity remains constrained in Pacific Island Countries. This scoping review examined health research output in the Cook Islands, Fiji, Guam, and Tonga from 2014 to 2024 following the...

Health research capacity is constrained in #PacificIslandCountries.

A scoping review in the #CookIslands, #Fiji, #Guam & #Tonga shows insufficient solution-focused studies and few studies had local authors - Calls for a greater local ownership, domestic #funding & ethical oversight.

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Effect of aspirin on small for gestational age neonates in pregnancies at high-risk for preeclampsia: a secondary analysis of a cluster randomised clinical trial Aspirin prophylaxis appears to be associated with a reduction in the rate of early-SGA and a simultaneous increase in the rate of late-SGA neonates born at or after 32 weeks. These findings underscore...

Small for gestational age #SGA neonates are at higher risk for adverse #perinatal outcomes.

An analysis of #FORECAST trial shows #aspirin prophylaxis was associated with reduced rate of early-SGA and increased rate of late-SGA neonates born >= 32 weeks 🧑‍🍼

🔗Full text #MedSky #ObGynSky #ReproSky