UW Infectious Disease Fellowship Program

Today we celebrated Dr. Steve Henikoff receiving the Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research. Dr. Henikoff will formally receive the award and present a lecture on his work next April @brandeisuniversity.bsky.social.

www.brandeis.edu/stories/2025...

Could the legionella be in the dispensing system (tubing/piping) which presumably would not be so cold?

#IDSky

Measles case associated with a domestic flight in a King County WA resident #IDSky #measles

A confirmed measles case in a vaccinated King County adult that was exposed to a previously reported measles case on an October 13, 2025 flight.

Exposure risk at link.

kingcounty.gov/en/dept/dph/...

Emergence, evolution and temporal spread of ceftriaxone-resistant Neisseria gonorrhoeae in China from 2002 to 2022: a retrospective genomic surveillance study Resistance to the last treatment option for gonorrhoea, ceftriaxone is a major public health concern globally, which poses a serious threat to the currently recommended ceftriaxone monotherapy. We ...

On our scary resistance radar - 357 not previously reported CTX resistant gonorrhea isolates… #IDSky

“Results suggest potential evolutionary pathways and directions of ceftriaxone-resistant strains…”

www.tandfonline.com/doi/full/10....

Tiger deaths in Vietnam due to infection with H5N1 highly pathogenic avian influenza virus bearing mutations associated with mammalian host adaptation Recently, infections with the H5N1 subtype of highly pathogenic avian influenza virus (H5N1-HPAIV) in mammals have been reported worldwide, including in cows in the United States and successive hum...

How diseases jump species - tiger deaths in Vietnam due to mammalian-host adapted H5N1… #IDSky #onehealth

www.tandfonline.com/doi/full/10....

Good news on the diagnostic stewardship front!

Review of practices in US acute care hospitals 2017-2020… #IDSky

Urine cx utilization decreased & the proportion of UCs with a positive UA increased. This may suggest a positive impact of diagnostic stewardship.

www.cambridge.org/core/journal...

Legionella from cold drinking water tap in hematology unit 😳

#IDSky

www.cambridge.org/core/journal...

Key recs:
- develop & support IPC program
- vax healthcare providers & residents
- establish priorities & standards for HAI surveillance
- regular hand hygiene, PPE when appropriate
- medical device ed
- infxn surveillance and POC testing
- dx & AMS

#IDSky

www.cambridge.org/core/journal...

Learn and have fun at the same time! (isn’t that what we always do?) :)

Yeah, sharing the info, but agree that it is underwhelming. Maybe an indication that we should try other approaches…

Great opportunity to learn outbreak investigation and setting up surveillance systems! #IDSky

New 2025 data shows COVID-19 vaccines provide effective, durable protection - UNC Gillings School of Global Public Health October 27, 2025 Updated COVID-19 vaccines are still providing effective protection against infection, emergency department visits, hospitalization and death, according to new research in JAMA led by ...

Data on level of protection from the 24-25 COVID vax:

At 4 weeks, ~45% protective against ED visit, 58% for hospitalization

Drops to 43/50% at 10 weeks and 40/34% at 20 weeks.

#IDSky #COVID #vaccine

sph.unc.edu/sph-news/new...

Original article 👉 jamanetwork.com/journals/jam...

71: Hotel Ice Machines: Don’t Get Slimed! - Germ & Worm Travel Medicine Podcast: Germ & Worm Ep. 71– From rafting hydraulics to typhoons, HPV, norovirus & travel vaccines

The Germ & Worm podcast, hosted by UW’s own Drs Paul Pottinger and Chris Sanford #IDSky #MedSky @paulpottingermd.bsky.social

germandworm.com/71-hotel-ice...

Consequences of Delaying Surgical Intervention in Patients with Native Joint Septic Arthritis AbstractBackground. Although recent guidance recommends early surgical debridement for native joint septic arthritis (NJSA), supporting data, particularly

10 yr retrospective cohort study of adults with native joint septic arthritis at Mayo, confirms what guidelines recommend - earlier surgical intervention is better, results in improved outcomes as compared to delayed intervention… #IDSky

academic.oup.com/ofid/advance...

Test of concept study - iodophor to reduce nasal carriage of c auris in long term care residents. Reduced burden in 52%, culture free in 19%. #IDSky #infectionprevention

academic.oup.com/ofid/advance...

More real-world evidence for RSV vaccines in the global community Respiratory syncytial virus (RSV) contributes to substantial disease burden among older adults, particularly those with chronic heart and lung conditions.1 In the UK, the Joint Committee on Vaccinatio...

Commentary:

www.thelancet.com/journals/lan... #IDSky #vaccines #RSV

Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England: a multicentre, test-negative, ca... This study provides evidence that the RSV pre-F vaccine is highly effective against RSV-associated hospital admissions, including exacerbations of chronic disease, and in adults with immunosuppression...

This multi center, case-control (all with acute respiratory infxn, cases RSV+) study of RSV vaccine effectiveness demonstrated 82.3% protection against hospitalization with RSV and 86.7% protection against severe disease. #IDSky #vaccines #RSV

www.thelancet.com/journals/lan...

Lancet ID in conversation with UW/FHCC’s Catherine Liu and Joshua Hill regarding prevention and management of infections in immunocompromise!! #IDSky

www.thelancet.com/doi/story/10...

The promise of lifelong vaccination A News piece in this issue reports on the sixth Conference on Vaccines hosted by the European Society of Clinical Microbiology and Infectious Diseases in Lisbon between Sept 10 and Sept 13. Adult immu...

“The success of initiatives aimed at improving adult vaccine uptake and delivery will probably determine the sustainability of global health systems more generally.”

www.thelancet.com/journals/lan...

Science for vaccine policy: Independent review of the September 2025 ACIP processes, deliberations and votes Since 1964, the Advisory Committee on Immunization Practices (ACIP) has shaped US vaccine policy but recently underwent significant structural and pro…

“Since 1964, ACIP has shaped US vaccine policy but recently underwent significant structural & procedural changes affecting recommendation quality. This paper presents analyses of the September 2025 ACIP meeting by former ACIP voting members.”
#IDSky #vaccines

www.sciencedirect.com/science/arti...

New data show hefty primary care RSV burden in young kids, older adults

This stood out 😳:
“Prescription drug use was reported in 61% of RSV episodes, with antibiotics (40%)”… #IDSky

Burden of RSV shouldered by little kiddos and older adults in these Dutch studies, with substantial primary care utilization.

www.cidrap.umn.edu/respiratory-...

Cool stats! also might be helpful @kenkoonwong.bsky.social to include #IDWeek in the post total - takes too long to type #IDWeek2025 and uses up characters…

Our most viewed and reposted skeet was shared via #IDWeek

Take it off the formulary :)

JID for Clinicians: The vaginal microbiome and HPV-related cancer, outpatient flu antiviral treatment and more Learn about the gut microbiome and clinical infections, flu-associated hospitalization rates and other research ready to inform clinical practice.

On IDSA’s & HIVMA’s Science Speaks blog: Learn about JID's latest monthly roundup of papers relevant to clinicians, including insights into the vaginal microbiome and HPV-related cancer, impacts of outpatient antiviral treatment on flu hospitalizations and more. https://bit.ly/3WqJ34w

Key points from the Medical Education article "Educational Strategies to Prepare Trainees for Clinical Uncertainty"

A new review focuses on the ways in which clinicians recognize and manage in-the-moment experiences of uncertainty in practice and provides practical strategies that teachers can use to help trainees build confidence in managing uncertainty. Read the full review: nej.md/43xKSQX

#MedSky #MedEd

The FHCC pumpkin carving contest!!! Finding Nemo anglerfish fish ❤️ @basicsci.fredhutch.org

Apparent antagonistic effect between voriconazole and olorofim with decreased zone of clearance around olorofim in presence of voriconazole in vitro -

needs more study of azole+olorofim and awareness as we start to use olorofim in practice … #IDSky

Rhipicephalus sanguineus sensu lato infestation in an urban area in South Sacramento, California, USA - Parasites & Vectors Background The brown dog tick, Rhipicephalus sanguineus sensu lato (Rh. sanguineus s.l.), is an important vector of Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever (RMSF), i...

Range expansion of rhipicephalus sanguineus, carrier of RMSF…

Penetration around Sacramento CA underscores need for continued surveillance, rapid response & community engagement to mitigate vector-borne disease risks #IDSky #climatechange

parasitesandvectors.biomedcentral.com/articles/10....

Co-occurrence of memory impairment and fatigue distinguishes post COVID from pandemic-related health effects in the 4-year CON-VINCE cohort study - Scientific Reports Scientific Reports - Co-occurrence of memory impairment and fatigue distinguishes post COVID from pandemic-related health effects in the 4-year CON-VINCE cohort study

The CON-VINCE cohort study of COVID 2020-2024, distinguishing post-COVID effects from general post pandemic effects…

Memory impairment and fatigue may help differentiate post-COVID from other pandemic effects. #IDSky #COVID #longCOVID

www.nature.com/articles/s41...