MRC Centre for Global Infectious Disease Analysis

Always wanted to learn about mathematical models of infectious diseases?

💼 This short course might be for you!
✨We offer a limited number of scholarships for participants from low- & middle-income countries
Find out more and apply 👇 www.imperial.ac.uk/mrc-global-i...
@imperialcollegeldn.bsky.social

A systematic review and meta-analysis of Zika virus epidemiology - Nature Health A systematic review including 574 studies extracts information about transmissibility, epidemiological delays and outbreaks for Zika virus disease at global scale.

Read more about this work in the @natureportfolio.nature.com Health publication👇
doi.org/10.1038/s443...
@imperialcollegeldn.bsky.social

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NEW EPISODE #ScienceInContext! This week @eonore.bsky.social speaks with Anna Vicco & Kelly McCain about Zika outbreaks, congenital Zika syndrome & next steps investigating the cross-reactivity of Zika with dengue 👇

youtu.be/u_7LpuG1Vpk
@imperialcollegeldn.bsky.social @anne-cori.bsky.social

Historical and current spatiotemporal patterns of wild and vaccine-derived poliovirus spread - Nature Microbiology Vaccine-derived poliovirus type 2 currently spreads similarly to historical poliovirus—unidirectionally across neighbouring countries at a median velocity of 2.3 km per day. International borders are ...

Find out more about historical and current spatiotemporal patterns of wild and vaccine-derived poliovirus spread in this Nature Microbiology paper 👇
@imperialcollegeldn.bsky.social @imperialsph.bsky.social
doi.org/10.1038/s415...

NEW EPISODE #ScienceInContext! This week Dr @eonore.bsky.social speaks with Dr Darlan Candido about historical transmission of poliovirus, immunity, cross border transmission and data availability👇
@imperialcollegeldn.bsky.social @imperialsph.bsky.social
youtu.be/SvRPfyHdNTg

Find out more about robust phylodynamic inference and model specification for HIV transmission dynamics in this Elsevier Epidemics publication 👇
@imperialcollege @ImperialSPH @erikmvolz @UCSanDiego
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doi.org/10.1016/j.ep...

It is #WorldAIDSDay! For this special #ScienceInContext Dr Fabricia Nascimento & Prof Sanjay Mehta join @eonore.bsky.social to speak about phylodynamic inference, HIV transmission, migration, genome sequencing & ethics
@imperialcollegeldn.bsky.social @ucsandiego.bsky.social 🧵1/2
youtu.be/SzdAhdjJuAE

Find out more & visit the CABBAGE platform 👇
@imperialcollegeldn.bsky.social @ebi.embl.org
www.ebi.ac.uk/amr

NEW EPISODE #ScienceInContext! It is World Antimicrobial Resistance #AMR Week. @eonore.bsky.social speaks with Dr Emily Dickens about CABBAGE, a new portal for comprehensive, global, curated AMR data for @who.int priority pathogens👇
youtu.be/G7EdE8Yb9rA
@imperialcollegeldn.bsky.social @ebi.embl.org

Surveillance getting GNASTy! Improving our ability to detect variants that haven’t been seen before! Optimizing nanopore adaptive sampling for pneumo surveillance in @genomeresearch.bsky.social 👇 doi.org/10.1101/gr.2... @imperialcollegeldn.bsky.social @ox.ac.uk @rebecca-and.bsky.social @ebi.embl.org

NEW EPISODE #ScienceInContext! @eonore.bsky.social joined by Dr Samuel Horsfield on diagnostic & surveillance methods & GNASTy improving our ability to detect variants that haven’t been seen before👇
@imperialcollegeldn.bsky.social @ox.ac.uk @rebecca-and.bsky.social @ebi.embl.org
youtu.be/X7I-ZVyw9dw

Read the full publication by Nic Steyn & @krisparag.bsky.social on the robust uncertainty quantification in popular estimators of the instantaneous reproduction number in the @amjepi.bsky.social👇
doi.org/10.1093/aje/...
@imperialcollegeldn.bsky.social @ox.ac.uk @imperialsph.bsky.social

NEW EPISODE #ScienceInContext! This week, Dr @eonore.bsky.social speaks with Dr @krisparag.bsky.social about methods to estimate the instantaneous reproduction number and approaches to estimate uncertainty 👇
@imperialcollegeldn.bsky.social @ox.ac.uk @rebecca-and.bsky.social
youtu.be/4DGD8ZWz4vg

Find out more about the @PacciProgramme 👇
web.pac-ci.org

NEW EPISODE #ScienceInContext this week @eonore.bsky.social speaks with Dr Romain Silhol, Dr Serge Niangoran and Kelly McCain to speak about a modelling workshop on HIV, HPV & cervical cancer in Côte d'Ivoire👇
youtu.be/N6w6Q73sidI

International collaborative effort to understand dengue and Zika | Imperial News | Imperial College London An international team launched the DeZi network to understand how the viruses spread, interact, and cause disease across Africa and Asia.

Find out more about this global initiative & insights from the team aiming to better understand dengue & Zika transmission, characterise arbovirus genetic diversity to inform public health strategies 👇
www.imperial.ac.uk/news/269973/...
@imperialcollegeldn.bsky.social sky.social @nfaria.bsky.social

International collaborative effort to understand dengue and Zika | Imperial News | Imperial College London An international team launched the DeZi network to understand how the viruses spread, interact, and cause disease across Africa and Asia.

Today we're kickstarting the Dengue & Zika Immunology & Genomics Multi-Country (DeZi) Network funded by @wellcometrust.bsky.social with contributions from @temasek.bsky.social @neasg.bsky.social #UNITEDengue
@imperialcollegeldn.bsky.social @nfaria.bsky.social
www.imperial.ac.uk/news/269973/...

Ep 134 Science in Context Fungal disease with Dr Harry Chown YouTube video by MRC Centre for Global Infectious Disease Analysis

NEW EPISODE #ScienceInContext! This week @eonore.bsky.social speaks with @chownbioinf.bsky.social about fungal disease, Aspergillus fumigatus and interactions with the soil it lives in. Harry shares his passions and insights from his work - one to watch 👇
youtu.be/ariW8UKVv-M

Read the full paper published in @thelancet.com HIV on the probability of vertical HIV transmission: a systematic review and meta-regression, here 👇
doi.org/10.1016/S235...

NEW EPISODE #ScienceinContext! This week, @eonore.bsky.social is joined by @mkwalters3.bsky.social to speak about HIV, vertical transmission, the impact of starting ART before & during pregnancy, and the importance of testing & treatment throughout pregnancy and breastfeeding 👇
youtu.be/xEEWT2QYkf0

Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions - Nature Medicine A modeling approach to assess the global risk of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions identifies ten priority African countries for surveillance and could inform malaria control policies.

NEW PUBLICATION! Read this full paper published today in @natureportfolio.nature.com Medicine on global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions👇

www.nature.com/articles/s41...

NEW EPISODE #ScienceInContext! @eonore.bsky.social is joined by @ojwatson.bsky.social @imperialcollegeldn.bsky.social to speak about the spread of hrp2/3 deletions, collaboration with the @who.int & what this research means for malaria control within the current funding climate👇
youtu.be/HhbD6rPtZSI

Quantifying the impact of a broadly protective sarbecovirus vaccine in a future SARS-X pandemic - Nature Communications Broad-spectrum vaccines have been proposed as a tool for rapid response to emerging infectious disease threats and are in pre-clinical development. Here, the authors use mathematical modelling to assess the potential impacts of broadly protective sarbecovirus vaccines for a hypothetical “SARS-X” outbreak.

NEW PUBLICATION! Check out this work in Nature Portfolio Communications quantifying the impact of a broadly protective sarbecovirus vaccine in a future SARS-X pandemic 👇
doi.org/10.1038/s414...

Quantifying the impact of a broadly protective sarbecovirus vaccine in a future SARS-X pandemic - Nature Communications Broad-spectrum vaccines have been proposed as a tool for rapid response to emerging infectious disease threats and are in pre-clinical development. Here, the authors use mathematical modelling to assess the potential impacts of broadly protective sarbecovirus vaccines for a hypothetical “SARS-X” outbreak.

NEW PUBLICATION! Check out this work in Nature Portfolio Communications quantifying the impact of a broadly protective sarbecovirus vaccine in a future SARS-X pandemic 👇
doi.org/10.1038/s414...
@imperialcollegeldn.bsky.social @imperialsph.bsky.social

CONGRATULATIONS! We celebrate the successful viva of Janetta Skarp who focussed on the gaps in knowledge regarding the quality of countries' outbreak response & the costs of outbreak response measures, & how these gaps could be addressed
@imperialcollegeldn.bsky.social @imperialsph.bsky.social

Modelling transmission of Middle East respiratory syndrome coronavirus in camel populations and the potential impact of animal vaccination - Nature Communications Outbreaks of Middle East respiratory syndrome coronavirus in humans are driven by spillover from camels, and vaccines for camels are in development. Here, the authors use mathematical modelling to explore transmission dynamics in camels and investigate potential impacts of vaccines.

Check out this publication @natureportfolio.nature.com Communications on modelling the transmission of Middle East respiratory syndrome coronavirus in camel populations and the potential impact of animal vaccination👇 doi.org/10.1038/s414...

NEW EPISODE #ScienceInContext! This week @eonore.bsky.social speaks with @amydighe.bsky.social about MERS-CoV in camels, vaccination strategies & how this can help prevent MERS-CoV in humans 👇
youtu.be/Eg_iQ4GtFVM
@imperialcollegeldn.bsky.social @imperialsph.bsky.social

Interested in Climate Amplified Diseases and Epidemics (CLIMADE)? Find out how this consortium predicts, tracks and controls diseases and epidemics in the most affected countries in the world 👇
climade.health

Genomic Surveillance of Climate-Amplified Cholera Outbreak, Malawi, 2022–2023 Genomic Surveillance of Cholera, Malawi, 2022–2023

Read this full paper published in Emerging Infectious Diseases on genomic surveillance of climate-amplified cholera outbreak, Malawi, 2022–2023👇
doi.org/10.3201/eid3...

NEW EPISODE #ScienceInContext! This week, @eonore.bsky.social speaks with Dr Monika Moir, Lucious Chabuka @suhealthsci.bsky.social & Christian Morgenstern @imperialcollegeldn.bsky.social about cholera in Malawi, climate change & climate amplified diseases & epidemics consortium👇
youtu.be/nvIfP6ANokk