Mito News

If you are interested in mitochondria, Nashville is the place to be June 1-5. Check out this FASEB meeting. Please RT. events.faseb.org/event/mitoch...

Mitochondria as sensors of intracellular pathogens Mitochondria must sense their environment to enable cells and organisms to adapt to diverse environments and survive during stress. However, during microbial infection, an evolutionary pressure since ...

Our opinion piece is out! My first published postdoc work with Lena Pernas. 🎉

Here, we speculate whether mitochondria can autonomously sense and elicit a response to microbes. 🤔🦠

#mitochondria #microbes

dlvr.it/TGLcRm

Hepatic mitochondrial respiration is crucial for euthermia in complex III-deficient mice with impaired brown adipose tissue thermogenesis Liver is the key hub of systemic energy metabolism and growth regulation, yet its roles in mitochondrial disease pathophysiology remain relatively understudied. Bcs1lp.S78G knock-in mice, carrying a p...

Our updated preprint out now! Started as rAAV gene therapy in mouse model of mitochondrial CIII deficiency, unexpectedly turned into a study of thermogenesis and BAT… and more. 😮 @awartiovaara.bsky.social @mito-news.bsky.social

Proud to announce the publication of our latest paper!

Huge thanks to all our collaborators for making this work possible. #Science #Mitochondria #Research #MitochondrialDisease #RareDiseases

www.embopress.org/doi/full/10....

PhD Opportunity Alert!🚨Please share!

Our lab is hiring a #PhD student! Join us in investigating #MitochondrialProteostasis and its role in #Ageing.

More Information here 👉 kohler-mitolab.com/join

#PhDPosition #Mitochondria #Science #JobOpportunity

Structural basis of 3′-tRNA maturation by the human mitochondrial RNase Z complex | The EMBO Journal imageimageThe human mitochondrial RNase Z complex is essential for the production of mitochondrial tRNAs. This study reveals its complete structural framework, detailing its role in tRNA maturation an...

Structural basis of 3′-tRNA maturation by the human mitochondrial RNase Z complex

www.embopress.org/doi/full/10....

#Mitochondria #Translation #tRNA

Dear fellow mitochondriacs! Here you can find this week's selection of papers on mitochondrial proteostasis, curated with the help of BiomedNews

👉 biomed.news/bims-mitpro/...

#Mitochondria #Proteostasis #Ageing #MitochondrialProteostasis #KohlerMitoLab

we are excited to join the community by sharing latest story from the lab where we show that mitochondrial pyruvate uptake is a critical step ATP production in hippocampal terminals and regulated by lysine acetylation of MPC. www.science.org/doi/full/10....

Stressed mitochondrial RNA granules from our recent work on the cover of PNAS!

A photo by E. Recazens illustrating our new story led by M. Foged on the cytosolic control of mitochondrial RNA processing and innate immunity by #N6AMT1.

#mitochondria #dsRNA

A cell photographed through a microscope. The powerhouses/overlords of the cell, #mitochondria (green), the world's busiest distribution center, Golgi apparatus (red), and a dynamic frame that gives the cell its shape, actin filaments (purple), are shown. #science #biology #cellbiology #microscopy

I’m excited to kick off a new series of #EM_Monday! Let’s start with mitochondria that act like magnets, aligning their cristae when they contact each other. This fascinating phenomenon has been reported before, such as in muscle tissue. doi.org/10.1038/ncom...

Metabolism starter pack now full with 150 contacts!
go.bsky.app/VavECSX

Mitochondrial pyruvate transport regulates presynaptic metabolism and neurotransmission The brain uses pyruvate as an energy source, and mitochondrial pyruvate metabolism in nerve terminals controls neurotransmission.

How do brain cells survive when glucose runs low? 🤔 Pyruvate to the rescue! New research in
@ScienceAdvances
shows how this fuel source steps up to protect neurons. #mitochondria #metabolism #neurons

www.science.org/doi/10.1126/...

Action Intent Links | Bluesky Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:

docs.bsky.app/docs/advance...

#AcademicSky #HigherEd #Altmetrics

The muscle of a heart photographed through an electron microscope. Pseudo-color shows the myosin II filaments that sit at the core of the #sarcomere (cyan), the borders of the sarcomere (purple), and #Mitochondria (pink)
#science #biology #cellbiology #microscopy #photography #cardiosky #medsky

Structural basis of respiratory complex adaptation to cold temperatures High-resolution structures of respiratory I:III2 complexes from brown fat adapted to cold temperatures reveal a distinct supercomplex assembly with rotated CIII2 that displays higher electron transfer...

In the latest issue of Cell- Structural basis of respiratory complex adaptation to cold temperatures

When will the journals migrate to Bluer skies?

🔬 Curious about #mitochondria #imaging but unsure where to begin? Our review might help! 🚀📜🧪

www.annualreviews.org/content/jour...

#Quantitative #Microscopy #SuperResolution #AcademicSky #ScienceSky #CellBiology #mtDNA

First #FluorescenceFriday in Bsky! 🔬 🧪 🐡
Starting with my reliable intro-slide partner, a vast #Mitochondria network 🟢 and nuclear DNA + #mtDNA 🟣

#AcademicSky #ScienceSky