Brenda Bass

Any academic folks on H1B visas (even with stamps in passports) please get legal advice from your University attorneys before leaving the US.

New #miRNA paper from Lai lab!! 🧬🔥

some think this field, despite recent Nobel to Ambros and Ruvkun, doesn't have much surprises left. but, do we EVEN KNOW WHAT a miRNA precursor LOOKS LIKE? we found some conserved miRNA hairpins up to 10x longer than suspected. this is mir-12, just bonkers! 1/n

🚨IT'S HAPPENING!🚨

Register now and join us in beautiful southern Chile in September for a new edition of the Molecular Biosystems Conference! @molbiosystems.bsky.social

SO wonderful to have you here Niladri!! We are so lucky!

Join — The Sinha Lab We welcome curiosity-driven individuals excited to make foundational discoveries aimed at understanding and combating defects in translational control and proteostasis in a dynamic, collaborative, and...

We are hiring at all levels, so please help spread the word! #RNAsky #ribosomes #signaling #translation sinha.biochem.utah.edu/join

Win Cash, Save Science: Share Your SciJourney! — Galactic Polymath Join the 2025 #MySciJourney Challenge! We are looking for scientists at all stages to share their journeys in science! Teachers: You and your students can help decide the winners! #scicomm #SaveNSF

🎉 We're so excited to announce the 2025 #MySciJourney Challenge: A #scicomm competition for researchers to share their authentic journeys in science with students, teachers, & the broader public! 🧪

💸 $1k in cash prizes, thanks to @ncse.bsky.social!
👉 www.galacticpolymath.com/blog/my-scij...

Joining an increasing number of people publicly demanding RFK’s removal as HHS Sec: Dr. Bill Foege, a literal (6’6”) & figurative giant of public health. He served as a CDC director under Carter & Reagan, & is credited with designing the ring vaccination strategy that enabled smallpox eradication.

"What I would simply say is cancer can't wait." --Richard Schlueter, a 56-year-old metastatic cancer patient whose therapy was delayed due to terminations at NIH.

Join the 22,339 people who have joined to support our NIH colleagues. Let's get this to 50,000 RT

I have been updating my dashboard (jeremymberg.github.io/jeremyberg.g...) to add important material about the #BethesdaDeclaration

1/n

"We are speaking on behalf of hundreds of NIH staff who are standing up together to say: WE DISSENT.

I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up."

Thank you to Dr. Jenna Norton and NIH scientists for your courage!

I don't see R35 MIRAs listed on the cited page of expired NOFOs. What am I missing?

This might be helpful:

www.regulations.gov/assets/files...

Improving Performance, Accountability and Responsiveness in the Civil Service The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...

The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23.

Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top:

www.federalregister.gov/documents/20...

6/n

Anyone have advice on how to justify a budget increase on a renewal of a senior MIRA? I know, dreaming, but want to dream right. thanks, thanks for any advice.

Integrator loss leads to dsRNA formation that triggers the integrated stress response Integrator (INT) prevents the escape of immature RNAPII to ensure full-length mRNA production. INT deficiency causes defects in RNAPII maturation that lead to premature termination, accumulation of immunogenic dsRNA, and activation of the integrated stress response (ISR) observed in patient cells.

Now online! Integrator loss leads to dsRNA formation that triggers the integrated stress response

Spent lots of time in balsam—recognized it immediately

Voting by mail – Elections Canada Apply to vote by mail, Eligible electors can apply to vote by special ballot. With a special ballot, you can vote by mail from anywhere in the world, 2025.

Canadians 🇨🇦 abroad - you can register to vote in the election! You need to do it soon. www.elections.ca/content2.asp...

Comprehensive Mapping of Human dsRNAome Reveals Conservation, Neuronal Enrichment, and Intermolecular Interactions The human transcriptome contains millions of A-to-I editing sites arising from an unclear number of poorly characterized dsRNAs. Editing sites are often used to infer presence of dsRNA, but this metho...

too much dsRNA? www.biorxiv.org/content/10.1...

For your enjoyment: here is Secretary of Education Linda McMahon talking about implementing AI in schools, but pronouncing it "A1," as in "A1 Steak Sauce"

www.youtube.com/live/lxrg28z...

we need to remember that these small wins are because people SPOKE UP -- keep calling your representatives, keep writing op-eds in your local papers, your voice matters! #resist

Harvard’s moment of truth - The Boston Globe The stakes are high, but the choice should not be difficult.

“a 400-year-old institution should be making decisions with a time horizon of centuries, not news cycles. Making a principled stand now…is the single best thing Harvard could do to earn its continued place as a symbol of genuine excellence”

www.bostonglobe.com/2025/04/04/o...

Really bad news here:

Make this go viral!

Her husband’s life was put at risk by the Signal texts.

www.eventbrite.com/e/stand-up-f...
please reskeet and spread the word! 🧪

Working on a story for @sfchronicle.com about the administration's impacts to science, including #NIH and #NSF funding. Hoping to chat with early-career scientists, especially grad students and postdocs, about how you've been affected. Thanks!

Signal: jacklee.55

Mark Cuban offers to fund government tech unit that was cut in the middle of the night | TechCrunch Billionaire investor Mark Cuban waded into the latest government tech shake-up on Saturday, offering support on the social network Bluesky for newly

I think it's going to happen: techcrunch.com/2025/03/01/m...

You did the right thing—absolutely. No question about it.

Great speech from Rep Jake Auchincloss (MA) - worth 3 mins of your time.

Scoop: FDA vaccine meeting abruptly canceled. Meeting was to determine 2025-2026 influenza vaccine composition. Hi everyone,

I believe we have breaking news in Inside Medicine.

I spoke to a member of the FDA vaccine committee who confirmed that the meeting to decide the 2025-2026 flu shot composition was abruptly canceled today.

My on-the-record Q&A with the FDA advisor:
insidemedicine.substack.com/p/scoop-fda-...