Jie Yang

One week left to apply for the postdoc position in my lab at Oxford @ox.ac.uk

Join our exciting cancer immunology research at @oncology.ox.ac.uk, @oxfordcancer.bsky.social & @oxcio.bsky.social.

Deadline: 11 August 2025 (noon).

We're recruiting a postdoc to join my lab at @oncology.ox.ac.uk & @oxcio.bsky.social to understand immune regulation in cancer and develop new approaches for cancer prevention and metastasis.

Deadline: 11 August 2025
my.corehr.com/pls/uoxrecru...

Lab info: www.oncology.ox.ac.uk/team/jie-yang

Low-dose aspirin to reduce recurrence rate in colorectal cancer patients with PI3K pathway alterations: 3-year results from a randomized placebo-controlled trial. LBA125Background: Colorectal cancer (CRC) affects 1.9 million individuals globally each year. Among patients with stage II-III CRC, 20-40% develop metastatic disease. Aspirin lowers the incidence of a...

New results from the ALASCCA prospective randomised controlled trial showing daily #aspirin reduces colorectal cancer recurrence by ~50% in patients with PIK3CA or related mutations. Findings extend benefits of aspirin beyond Lynch syndrome cancers to nearly 40% of CRCs ascopubs.org/doi/10.1200/...

Aspirin helps T cells to stop cancer spread - Nature Reviews Immunology Drugs like aspirin can enhance the anti-metastatic activity of T cells by blocking a platelet-mediated pathway of suppression.

Research Highlight of our recent paper by @jieyang437.bsky.social on Aspirin and cancer metastasis in Nature Reviews Immunology. Thanks to Yvonne Bordon for a crystal clear account of the experimental findings www.nature.com/articles/s41...

Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity - Nature Inhibition of cyclooxygenase 1 releases T cells from immunosuppression by platelet-derived thromboxane A2, thereby enhancing the immune response against metastasis.

Congrats to @jieyang437.bsky.social & Rahul for this awesome work on metastasis

www.nature.com/articles/s41...

Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity - Nature Inhibition of cyclooxygenase 1 releases T cells from immunosuppression by platelet-derived thromboxane A2, thereby enhancing the immune response against metastasis.

Brilliant new paper from Jie Yang @jieyang437.bsky.social and Rahul Roychoudhuri @roychoudhurilab.bsky.social linking aspirin to immune-mediated prevention of cancer metastasis.
www.nature.com/articles/s41...

Thanks, Seth

Thanks, Tim. It's an incredible journey together with Rahul.