Fabrice Jean-Pierre

"Super-exponential growth cannot continue for much longer. By its very nature, it is ephemeral and unsustainable. Stationary phase will start soon."

Strengthening phage resistance of Streptococcus thermophilus by leveraging complementary defense systems - Nature Communications A study by Leprince et al. shows the effectiveness of Streptococcus thermophilus defense systems against dairy phages, their synergy with CRISPR-Cas, and the absence of fitness cost under lab or indus...

😮 Cool work from Sylvain Moineau

#phage #phagesky

www.nature.com/articles/s41...

Research position in Microbial Pharmacology and Population Biology (282139) | UiT The Arctic University of Norway Job title: Research position in Microbial Pharmacology and Population Biology (282139), Employer: UiT The Arctic University of Norway, Deadline: Wednesday, August 27, 2025

Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you
www.jobbnorge.no/en/available...

I am excited to announce that the position of a senior postdoc (3 +3 years) in the field of theoretical biology is available in my group.

The position provides the opportunity to closely interact with experimentalists and develop own research projects.

Please RT.

Details 👇:
shorturl.at/iiiOv

CRISPRi-seq in Haemophilus influenzae reveals genome-wide and medium-specific growth determinants Work in the human pathobiont Haemophilus influenzae has pioneered functional genomics in bacteria such as genome-wide transposon mutagenesis combined with deep sequencing. These approaches unveiled a ...

New tools for the important opportunistic human bacterial pathogen Haemophilus influenzae #MicroSky: www.biorxiv.org/content/10.1...

Hey #MicroSky! I’m at Phages and like any great conference, cool science ideas come up. Does anyone have a lead on how I can get the E. coli Keio collection pre-mixed for a screen?? Send me a DM 🙏🏾

"ecosystems are almost invariably extremely complex. But to understand them, they can be (and perhaps even should be) simplified." #microsky

journals.asm.org/doi/epdf/10....

What to expect at the ASM Biofilms Conference #ASMBiofilms
(Today 08/06/25 is the last day for abstract submission!)

Super excited to share our paper online 🚨today🚨 in Cell Host & Microbe‬! Xiaomei Ren @xiaomeiren.bsky.social and Mason Clark @rmasonclark.bsky.social‬ co-led discovery of ecological factors for Acinetobacter baumannii carriage in the gut, a reservoir for pathogen spread. 🎉

tinyurl.com/443kfefk

Mechanistic study of a low-power bacterial maintenance state using high-throughput electrochemistry Anaerobic phenazine cycling by an opportunistic bacterial pathogen supports a low-power, non-growth metabolism that lends itself to quantitative and mechanistic study of maintenance physiology.

Dianne Newman: beautiful demonstration of maintenance metabolism in #Psuedomonas, which uses PCN redox cycling to support PMF during anaerobic growth #Phages2025

www.cell.com/cell/abstrac...

New Microbial Primer published by the @microbiologysociety.org on agr-mediated quorum sensing in Gram-positive pathogens. Explore the full Primer collection here www.microbiologyresearch.org/content/micr...

"The entities enabling scientific fraud at scale are large, resilient, and growing rapidly" #microsky

www.pnas.org/doi/10.1073/...

New in JB: Fabri, Olson et al. electron transfer enzymes for ferredoxin in Thermoanaerobacterium saccharolyticum.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

12 tiny worlds Podcast Episode · Unexplainable · 07/30/2025 · 38m

So delighted that the #LTEE landed in my podcast feed today! Great job as always @relenski.bsky.social !

Don’t miss this one!
podcasts.apple.com/us/podcast/u...

Extremely proud of my postdoc Dr. Elizabeth Knorr for successfully mentoring 5 undergrad research students through several cloning projects this summer!!! Congrats to the mini Knorr Lab! @cmuscience.bsky.social

PNAS and PNAS Nexus Logos Early-Career Researcher Workshop Friday, September 12 Button: I'm Interested

@pnas.org is hosting a virtual Early-Career Researcher (ECR) Workshop on September 12 from 1–2:30 PM (EDT) to discuss how ECRs can engage with PNAS Special Features, what defines a strong article, and more. Seats are limited, and we’re gauging interest via this survey: www.surveymonkey.com/r/XZ9N6PG

Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms

led by @abultarafder.bsky.social

Great collaboration with @pearce-maths.bsky.social and @geiselbiofilm.bsky.social

www.biorxiv.org/cgi/content/...

JB Table of Contents Volume 207, Issue 7 Journal of Bacteriology: Table of Contents Volume 207, Issue 7

In the July issue of JB: Cell walls, cell division, gluconate metabolism, electron transfer, membranes, spres, Abx-r, efflux pumps, chromosome replication, toxin delivery, surface sensing and more.
journals.asm.org/toc/jb/207/7
@asm.org #JBacteriology

ExcludonFinder: mapping transcriptional overlaps between neighboring genes Abstract. Bacteria regulate neighboring genes via overlapping transcription in untranslated regions (UTRs), forming excludons. This overlap leads to transc

🚨🚨 New paper in @narjournal.bsky.social! 🍾

Excludons are pairs of overlapping genes that block each other’s expression (basically, reverse operons).

We built a tool to identify them in bacterial genomes using transcriptomic data, in an awesome collab led by Iñigo Lasa and Álvaro San Martín.

👇

Call for 20 Assistant Professor positions Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

Wow

Karolinska Institutet is recruiting 20 outstanding early-career researchers for assistant professor positions

ki.se/en/about-ki/...

Strategies and mechanisms of contact-dependent predation in bacteria Predatory bacteria kill other bacteria to acquire nutrients. Among diverse strategies to kill and feed on prey, contact-dependent predation stands out…

#MicroSky Summer read!

Predatory bacteria kill and eat other bacteria. Their deadly actions come in many flavors, often via direct physical contact between predator &
prey 🧛

How do they do it?
Our review 📖 @coralietesseur.bsky.social @ysantin.bsky.social

www.sciencedirect.com/science/arti...

Fifteen years later, Science retracts ‘arsenic life’ paper despite study authors’ protests Belated decision on widely disputed 2010 study pleases some critics but puzzles and dismays others

Science finally retracts the Arsenic life paper www.science.org/content/arti...

Microbiology professor, want to join a slack for microbiology professors, any career stage, diverse career types (pure teaching, med school, R1, community college, pure research fed PIs, ...)

Message me for an invite link if you are interested.

No imposter syndrome, if you are 1% micro, join!

Things are getting busy at Microbial DIversity. Lab on the first day (left) and lab yesterday! @mblscience.bsky.social

Humanity’s urgent challenges need solutions from systems microbiology | mSystems It is with great excitement and sincere dedication that I assume the role of editor in chief of mSystems. Building on the momentum and reputation that mSystems has achieved in its first decade, we wil...

Meet the new Editor in Chief of mSystems journals.asm.org/doi/10.1128/...

Editor's Pick: Shen, Ye et al. review recent literature on the role of bacterial ribosome heterogeneity on facilitating rapid response to stress.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

Exploring the Gut-Lung Axis in Health and Disease In this webinar, George O’Toole and Jorge Cervantes will discuss how researchers study the communication between the gut and lung in normal and disease states.

A few days ago I had the chance to talk about our work on the gut-lung axis in cystic fibrosis as part of a webinar with The Scientist magazine. You can check it out here (I am the first speaker): www.the-scientist.com/exploring-th...

Respiratory viral infection is associated with increased Pseudomonas abundance in cystic fibrosis airways Acute respiratory viral infections are an important driver of morbidity and mortality in people with chronic lung disease and are frequently associated with pulmonary exacerbations and a transition fr...

"Respiratory viral infection is associated with increased Pseudomonas abundance in cystic fibrosis airways"

www.biorxiv.org/content/10.1...

A single point mutation is sufficient to drive syp-dependent biofilm formation and promote colonization by Vibrio fischeri | Journal of Bacteriology Biofilms promote the attachment of bacteria to each other and to surfaces. For Vibrio fischeri, biofilm formation dependent on the symbiosis polysaccharide (syp) locus promotes colonization of its sym...

Great work from Karen Visick @microklv.bsky.social lab on fan-favorite Vibrio fischeri and its adorable 🐙 host.

A single point mutation is sufficient to drive syp-dependent
biofilm formation and promote colonization by Vibrio fischeri

h/t @seqcoast.bsky.social

journals.asm.org/doi/10.1128/...

CIHR rant here: our panel funded 6 (!!) out of 42 applications. That is only 14% success rate. That is as bad as the worst of times. So much good science left unfunded, labs closing, skilled workers let go. Without a $$ infusion, the Canadian research ecosystem is never going to survive and thrive.