Bilinguals scored lower on naming, but both groups showed worse performance with left onset epilepsy.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #bilingualism #language #lateralization #neuropsychology
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Epilepsia® – A Journal of the ILAE Epilepsia® is the world's leading journal of original scientific research and commentary in epileptology. Impact Factor: 6.6. Epilepsia® publishes original articles on all aspects of epilepsy, clinical and experimental. T
Bilinguals scored lower on naming, but both groups showed worse performance with left onset epilepsy.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #bilingualism #language #lateralization #neuropsychology
A deep learning CNN-BiLSTM algorithm was used to identify seizures in two-channel subscalp EEG data from three centers.
onlinelibrary.wiley.com/doi/full/10....
#epilepsy #ILAE #epilepsia #deeplearning #neurology #seizure #subcutaneousEEG
The dropout rate of MAD in adults with DRE was high, and most patients discontinued diet in the first 6 months, mainly for noncompliance.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #compliance #dropout #ketogenicdiet #sideeffects
The Digital Response Test in Epilepsy (DigRTEpi) provides time-locked analysis of interictal epileptiform discharge (IED) effects.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #drivingsafety #EEG #interictalepileptiformdischarge #machinelearning #transitorycognitiveimpairment
New in Epilepsia – October 11, 2025
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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch
Lack of early status epilepticus delayed genetic testing for Dravet syndrome.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #Dravetsyndrome #epilepsygenetics #genetictesting #healthequity #SCN1A
Long-term memory trajectories after epilepsy surgery for TLE/HS show a tendency toward delayed decline, even in seizure-free patients.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #epilepsysurgery #hippocampalsclerosis #memory #temporallobeepilepsy
These results reflect that abnormalities gathered from T1w MRI is useful in delineation of response groups to VNS, and, specifically, that hippocampal damage could be considered when offering VNS to individuals with DRE.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #biomarker #MRI
PEH had a higher burden of psychiatric symptomatology than housed people with epilepsy. Once psychiatric symptomatology was controlled for, there was no difference in quality of life.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #homelessness #mentalhealth
Proteomic and phosphoproteomic analyses reveal dysregulated pathways linked to axonal development and synaptic function.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #BRSK1 #lossoffunction #neurodevelopmentaldisorders
To advance procedures to select optimal treatment regimens for patients with SCN8A-related epilepsy, we construct an ML algorithm to recommend ASMs based on caregiver assessments.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #machinelearning #pediatricepilepsy #rarediseases #SCN8A
Stereotactic radiofrequency thermocoagulation achieved 60% seizure freedom at 12 months using fewer trajectories than previously reported approaches.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #gelasticseizures #hypothalamichamartoma #refractoryepilepsy #surgicaloutcome
New in Epilepsia – October 4, 2025
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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch
γ-Aminobutyric acid B receptor (GABABR)-IgG (immunoglobulin G) autoimmune encephalitis often presents as encephalopathy with seizures in the context of underlying small cell lung carcinoma.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #antiGABABreceptor #autoimmuneencephalitis
New Special Issue in Epilepsia: AI, Wearables & Digital Health in Epilepsy
🔗 onlinelibrary.wiley.com/toc/15281167...
#Epilepsia #EpilepsyResearch #DigitalHealth #AI #Wearables #SeizureDetection #PatientCare #epilepsy #ILAE
In univariate analyses, decreased cortical and subcortical metabolism on FDG-PET was a stronger discriminator of dysplastic cortex than surface-based MRI features.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #artificialintelligence #epilepsysurgery #multimodalneuroimaging #AI
Atenolol reduced heart rate and QTc interval, without affecting seizure load in both mouse models of SUDEP.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #atenolol #cardiacarrhythmia #KCNH2 #longQTsyndrome #SUDEP
A holistic, biopsychosocial approach benefits all seizure patients and reflects modern models of epilepsy care.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #epilepticseizures #functionaldissociativeseizures
A significant discrepancy is noted in the availability of cannabinoids for the treatment of epilepsy across different geographic settings.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #cannabidiol #cannabinoids #CBD #plantbasedtherapy
Letter to the Editor
Open Access
The epileptic heart: Let's not forget to look at the atria!
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #heart #atria #atrialfibrillation #myocardialstrain
PWEs and CGs generally support AI-CLDs for SUDEP prevention but emphasize the need for accuracy, reliability, and user control over interventions.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #artificialintelligence #automatedintervention #closedloopsystem #medicaldevice #SUDEP
Volume electron microscopy revealed ultrastructural synaptic and organelle changes in the cortex of a patient with FCD.
doi.org/10.1111/epi....
#epilepsy #epilepsia #ILAE #cortex #electronmicroscopy #hyperexcitability #mitochondria #synapse
Interictal low-entropy activity marks epileptogenic zones even without visible spikes or seizures in intracranial electroencephalography (iEEG).
doi.org/10.1111/epi....
#epilepsy #epilepsia #ILAE #entropy #epilepsysurgery #interictaldata #intracranialEEG #outcomeprediction
New in Epilepsia – September 27, 2025
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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch
KCC2 mitigates ictal-like events and their propagation in supragranular layers of neocortical acute brain slices from the seizure propagation zone of TLE patients.
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #chloridehomeostasis #KCC2 #microelectrodeArray #seizurepropagation
Our findings identify augmented ventilatory chemosensitivity and impaired autoresuscitation as critical pathophysiological features of SUDEP.
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #anoxia #autoresuscitation #chemosensing #respiration #SUDEP
Witness recall was experimentally tested 2 and 7 weeks after seeing a seizure, mirroring typical “first seizure” clinic wait times.
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #accuratediagnosis #firstseizures #recall #waitingtimes #witnesses
New in Epilepsia – September 20, 2025
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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch
The resulting lesion network causing HKS was aligned with the hypometabolic patterns observed in HKS via positron emission tomography–computed tomography.
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #DBS #functionalconnectivity #MRI #hyperkineticseizures #lesionnetworkmapping
Task-induced high-frequency activity (HFA) is a marker of cortical processing and a promising functional mapping approach for SEEG.
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #directcorticalstimulation #epilepsysurgery #functionalmapping #highfrequencyactivity #presurgicalevaluation #SEEG