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Epilepsia Journal

@epilepsiajournal.bsky.social

Epilepsia® – A Journal of the ILAE Epilepsia® is the world's leading journal of original scientific research and commentary in epileptology. Impact Factor: 6.6. Epilepsia® publishes original articles on all aspects of epilepsy, clinical and experimental. T

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Bilinguals scored lower on naming, but both groups showed worse performance with left onset epilepsy.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #bilingualism #language #lateralization #neuropsychology

16.10.2025 18:03 — 👍 0    🔁 0    💬 0    📌 0
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A deep learning CNN-BiLSTM algorithm was used to identify seizures in two-channel subscalp EEG data from three centers.
onlinelibrary.wiley.com/doi/full/10....

#epilepsy #ILAE #epilepsia #deeplearning #neurology #seizure #subcutaneousEEG

16.10.2025 18:02 — 👍 0    🔁 0    💬 0    📌 0
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The dropout rate of MAD in adults with DRE was high, and most patients discontinued diet in the first 6 months, mainly for noncompliance.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #compliance #dropout #ketogenicdiet #sideeffects

15.10.2025 19:59 — 👍 0    🔁 0    💬 0    📌 0
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The Digital Response Test in Epilepsy (DigRTEpi) provides time-locked analysis of interictal epileptiform discharge (IED) effects.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #drivingsafety #EEG #interictalepileptiformdischarge #machinelearning #transitorycognitiveimpairment

15.10.2025 19:54 — 👍 0    🔁 0    💬 0    📌 0
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New in Epilepsia – October 11, 2025
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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch

13.10.2025 18:58 — 👍 0    🔁 0    💬 0    📌 0
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Lack of early status epilepticus delayed genetic testing for Dravet syndrome.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #Dravetsyndrome #epilepsygenetics #genetictesting #healthequity #SCN1A

13.10.2025 18:56 — 👍 0    🔁 0    💬 0    📌 0
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Long-term memory trajectories after epilepsy surgery for TLE/HS show a tendency toward delayed decline, even in seizure-free patients.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #epilepsysurgery #hippocampalsclerosis #memory #temporallobeepilepsy

10.10.2025 15:59 — 👍 1    🔁 0    💬 0    📌 0
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These results reflect that abnormalities gathered from T1w MRI is useful in delineation of response groups to VNS, and, specifically, that hippocampal damage could be considered when offering VNS to individuals with DRE.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #biomarker #MRI

10.10.2025 15:58 — 👍 1    🔁 1    💬 1    📌 0
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PEH had a higher burden of psychiatric symptomatology than housed people with epilepsy. Once psychiatric symptomatology was controlled for, there was no difference in quality of life.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #homelessness #mentalhealth

09.10.2025 16:32 — 👍 0    🔁 0    💬 0    📌 0
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Proteomic and phosphoproteomic analyses reveal dysregulated pathways linked to axonal development and synaptic function.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #BRSK1 #lossoffunction #neurodevelopmentaldisorders

09.10.2025 16:31 — 👍 0    🔁 0    💬 0    📌 0
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To advance procedures to select optimal treatment regimens for patients with SCN8A-related epilepsy, we construct an ML algorithm to recommend ASMs based on caregiver assessments.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #machinelearning #pediatricepilepsy #rarediseases #SCN8A

08.10.2025 14:47 — 👍 0    🔁 0    💬 0    📌 0
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Stereotactic radiofrequency thermocoagulation achieved 60% seizure freedom at 12 months using fewer trajectories than previously reported approaches.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #gelasticseizures #hypothalamichamartoma #refractoryepilepsy #surgicaloutcome

07.10.2025 15:50 — 👍 0    🔁 0    💬 0    📌 0
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New in Epilepsia – October 4, 2025
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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch

06.10.2025 20:02 — 👍 0    🔁 0    💬 0    📌 0
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γ-Aminobutyric acid B receptor (GABABR)-IgG (immunoglobulin G) autoimmune encephalitis often presents as encephalopathy with seizures in the context of underlying small cell lung carcinoma.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #antiGABABreceptor #autoimmuneencephalitis

06.10.2025 20:02 — 👍 0    🔁 0    💬 0    📌 0
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New Special Issue in Epilepsia: AI, Wearables & Digital Health in Epilepsy⁠
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🔗 onlinelibrary.wiley.com/toc/15281167...

#Epilepsia #EpilepsyResearch #DigitalHealth #AI #Wearables #SeizureDetection #PatientCare #epilepsy #ILAE

03.10.2025 14:18 — 👍 0    🔁 0    💬 0    📌 0
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In univariate analyses, decreased cortical and subcortical metabolism on FDG-PET was a stronger discriminator of dysplastic cortex than surface-based MRI features.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #artificialintelligence #epilepsysurgery #multimodalneuroimaging #AI

03.10.2025 14:16 — 👍 1    🔁 0    💬 0    📌 0
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Atenolol reduced heart rate and QTc interval, without affecting seizure load in both mouse models of SUDEP.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #atenolol #cardiacarrhythmia #KCNH2 #longQTsyndrome #SUDEP

02.10.2025 13:43 — 👍 2    🔁 0    💬 0    📌 0
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A holistic, biopsychosocial approach benefits all seizure patients and reflects modern models of epilepsy care.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #epilepticseizures #functionaldissociativeseizures

02.10.2025 13:42 — 👍 0    🔁 0    💬 0    📌 0
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A significant discrepancy is noted in the availability of cannabinoids for the treatment of epilepsy across different geographic settings.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #cannabidiol #cannabinoids #CBD #plantbasedtherapy

01.10.2025 20:13 — 👍 0    🔁 0    💬 0    📌 0
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The epileptic heart: Let's not forget to look at the atria! Click on the article title to read more.

Letter to the Editor
Open Access

The epileptic heart: Let's not forget to look at the atria!
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #heart #atria #atrialfibrillation #myocardialstrain

01.10.2025 20:12 — 👍 1    🔁 0    💬 0    📌 0
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PWEs and CGs generally support AI-CLDs for SUDEP prevention but emphasize the need for accuracy, reliability, and user control over interventions.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #artificialintelligence #automatedintervention #closedloopsystem #medicaldevice #SUDEP

30.09.2025 15:48 — 👍 3    🔁 0    💬 0    📌 0
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Volume electron microscopy revealed ultrastructural synaptic and organelle changes in the cortex of a patient with FCD.
doi.org/10.1111/epi....

#epilepsy #epilepsia #ILAE #cortex #electronmicroscopy #hyperexcitability #mitochondria #synapse

30.09.2025 15:47 — 👍 0    🔁 0    💬 0    📌 0
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Interictal low-entropy activity marks epileptogenic zones even without visible spikes or seizures in intracranial electroencephalography (iEEG).
doi.org/10.1111/epi....

#epilepsy #epilepsia #ILAE #entropy #epilepsysurgery #interictaldata #intracranialEEG #outcomeprediction

29.09.2025 21:06 — 👍 1    🔁 0    💬 0    📌 0
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New in Epilepsia – September 27, 2025
mailchi.mp/ilae/new-art...

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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch

29.09.2025 21:04 — 👍 0    🔁 0    💬 0    📌 0
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Potassium–chloride cotransporter 2 activity dampens induced ictal‐like activity in neocortical slices containing the seizure propagation zone of temporal lobe epilepsy patients The K⁺/Cl− cotransporter (KCC2) limits induced ictal-like events and their spread in the supragranular layer of human neocortical slices from the seizure-propagation zone of temporal lobe epilepsy pa...

KCC2 mitigates ictal-like events and their propagation in supragranular layers of neocortical acute brain slices from the seizure propagation zone of TLE patients.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #chloridehomeostasis #KCC2 #microelectrodeArray #seizurepropagation

23.09.2025 21:31 — 👍 0    🔁 0    💬 0    📌 0
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Our findings identify augmented ventilatory chemosensitivity and impaired autoresuscitation as critical pathophysiological features of SUDEP.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #anoxia #autoresuscitation #chemosensing #respiration #SUDEP

23.09.2025 21:30 — 👍 0    🔁 0    💬 0    📌 0
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Witness recall was experimentally tested 2 and 7 weeks after seeing a seizure, mirroring typical “first seizure” clinic wait times.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #accuratediagnosis #firstseizures #recall #waitingtimes #witnesses

22.09.2025 17:10 — 👍 1    🔁 0    💬 0    📌 0
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New in Epilepsia – September 20, 2025
mailchi.mp/ilae/new-art...

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#epilepsy #epilepsia #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch

22.09.2025 17:09 — 👍 1    🔁 0    💬 0    📌 0
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The resulting lesion network causing HKS was aligned with the hypometabolic patterns observed in HKS via positron emission tomography–computed tomography.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #DBS #functionalconnectivity #MRI #hyperkineticseizures #lesionnetworkmapping

19.09.2025 15:40 — 👍 1    🔁 0    💬 0    📌 0
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Task-induced high-frequency activity (HFA) is a marker of cortical processing and a promising functional mapping approach for SEEG.
doi.org/10.1111/epi....

#epilepsy #ILAE #Epilepsia #directcorticalstimulation #epilepsysurgery #functionalmapping #highfrequencyactivity #presurgicalevaluation #SEEG

19.09.2025 15:38 — 👍 2    🔁 1    💬 0    📌 0

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