CD4+ mucosal-associated invariant T cells express highly diverse T cell receptors Abstract. Mucosal-associated invariant T (MAIT) cells are highly conserved innate-like T cells in mammals recognized for their high baseline frequency in h

We are pleased to share our new publication linking TRAV1-2 negative MAIT cells, CD4 coexpression, and tuberculosis. A conserved innate-like T cell subset with more TCR diversity than previously appreciated. academic.oup.com/jimmunol/adv... #Immunology #maitcells #TCRdiversity

13.11.2025 19:46 — 👍 0    🔁 0    💬 0    📌 0

Thank you @bsheridanlab.bsky.social. We are excited about sharing this work, particularly in light of parallel findings in IV BCG vaccination models in macaques that demonstrate CD8aa+ lymphocytes are critical for controlling Mtb. Can NK cells recognize specific MHC I-epitope complexes? TBD

02.05.2025 18:29 — 👍 1    🔁 0    💬 0    📌 0