David SΓΌnderhauf's Avatar

David SΓΌnderhauf

@davvi36.bsky.social

Microbiologist at the University of Exeter: AMR🧫 | Loves plasmids & MGEs | Green Councillor on Truro City Council 🌿 | Would love to do more sci-comm in Cornwall 〓〓 | he/him Promoted by David SΓΌnderhauf (Green Party), at 17 Great George St, Bristol BS1 5

1,096 Followers  |  690 Following  |  109 Posts  |  Joined: 04.09.2023  |  1.9052

Latest posts by davvi36.bsky.social on Bluesky

Phage resistance research position with a fantastic supervisor πŸ‘‡

08.08.2025 08:13 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Research position in Microbial Pharmacology and Population Biology (282139) | UiT The Arctic University of Norway Job title: Research position in Microbial Pharmacology and Population Biology (282139), Employer: UiT The Arctic University of Norway, Deadline: Wednesday, August 27, 2025

Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you
www.jobbnorge.no/en/available...

08.08.2025 07:52 β€” πŸ‘ 60    πŸ” 58    πŸ’¬ 1    πŸ“Œ 4

Congratulations, very happy for you 😁😁

06.08.2025 09:07 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Great, I'll gamble on the exchange rate and pay in EC dollar now πŸπŸ’΅ come onnnn November 🀞🏻

05.08.2025 19:57 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Brilliant idea!

05.08.2025 16:07 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Want to name a real virus? I have recently discovered 9 new phages which now need names! To enter, you simply need to donate to the Cystic Fibrosis Trust on my JustGiving page (Β£2 = 1 entry) and share your email with me on donation (see link info). Please share πŸ’š www.justgiving.com/page/meaghan-c-1

05.08.2025 12:45 β€” πŸ‘ 30    πŸ” 25    πŸ’¬ 2    πŸ“Œ 2
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Strategies for zygotic gene expression during plasmid establishment Conjugative plasmids are key drivers of horizontal gene transfer and the spread of antimicrobial resistance. Their successful establishment in new hos…

Plasmid leading regions & their contribution to plasmid establishment are all the rage in the plasmid world right now. This review summarizes why πŸ‘‰ www.sciencedirect.com/science/arti...

24.07.2025 10:47 β€” πŸ‘ 14    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
2025 Phage Therapy Workshop - Free Event November 25th, 2025 at the Spine Building in Liverpool Rising levels of antimicrobial resistance threaten healthcare systems and economies worldwide. Phage therapy has proven to be an effective last-r...

Hopefully this link actually works:
sites.exeter.ac.uk/vanhoutelab/...

22.07.2025 20:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Conference flyer, all info is on link too

Conference flyer, all info is on link too

Please share! 🦠
Workshop on Phage Therapy in Liverpool on 25th November organised by Stineke van Houte, @jojofoth.bsky.social, @brockhurstlab.bsky.social, & Edze Westra.

Limited FREE tickets & more info here: sites.exeter.ac.uk/vanhoutelab/...

#MicroSky

22.07.2025 19:03 β€” πŸ‘ 14    πŸ” 13    πŸ’¬ 2    πŸ“Œ 0

Looks great, congrats all!

17.07.2025 10:40 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium pRUM-like plasmids are commonly found in multidrug-resistant Enterococcus faecium , but the evolution of these plasmids has not been characterised in detail. When we analysed the genome sequences of t...

New manuscript from the group

'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium'

www.biorxiv.org/content/10.1...

/1

17.07.2025 08:39 β€” πŸ‘ 28    πŸ” 13    πŸ’¬ 3    πŸ“Œ 2

Congratulations, this looks great! I'll send you an email re antibiotic resistance genes moving onto the chromosome.

16.07.2025 10:35 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Chromosomal capture of beneficial genes drives plasmids toward ecological redundancy Abstract. Plasmids are a ubiquitous feature of bacterial genomes, but the forces driving genes and phenotypes to become associated with plasmids are poorly

New paper with @rwheatley8.bsky.social and Cedric Lood

Actual title: Chromosomal capture of beneficial genes drives plasmids towards ecological redundancy.

Sensationalist title: Plasmids carry useless genes

academic.oup.com/ismej/articl...

16.07.2025 09:17 β€” πŸ‘ 74    πŸ” 30    πŸ’¬ 4    πŸ“Œ 1
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Scaling laws of bacterial and archaeal plasmids - Nature Communications The capacity of a plasmid to express genes is constrained by parameters such as its length and copy number. Here, Maddamsetti et al. present a computational method that enables rapid and accurate dete...

Scaling laws of bacterial and archaeal plasmids www.nature.com/articles/s41... #jcampubs

02.07.2025 15:34 β€” πŸ‘ 37    πŸ” 13    πŸ’¬ 1    πŸ“Œ 0

Congrats on getting this out! I loved hearing about this at ISPB & enjoyed the preprint 😊

02.07.2025 13:55 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Universal rules govern plasmid copy number - Nature Communications Plasmids exhibit a broad range of sizes and copies per cell, and these two parameters appear to be negatively correlated. Here, Ramiro-MartΓ­nez et al. analyse the copy number of thousands of diverse b...

Curious about plasmid biology? Our latest paper is out now in Nature Communications! 🚨

doi.org/10.1038/s414...

We analyzed thousands of diverse bacterial plasmids to shed light for the first time on a key aspect of plasmid biology: plasmid copy number. 1/7 πŸ‘‡

02.07.2025 10:07 β€” πŸ‘ 80    πŸ” 39    πŸ’¬ 4    πŸ“Œ 4
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UK to expand nuclear deterrent with US fighter jets capable of carrying warheads Starmer to unveil purchase of 12 F-35A jets that can deliver tactical nuclear weapons, which may be kept at RAF bases

An absolutely horrible idea to store nuclear bombs in the UK which belong to a country that looks far too close to a proto-fascist regime for comfort

UK to expand nuclear deterrent with US fighter jets capable of carrying warheads www.theguardian.com/politics/202...

25.06.2025 09:47 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

You're on fire Meaghan πŸ”₯ Congrats!

24.06.2025 15:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Predicting clinical phage therapy outcomes in vitro: results using mixed versus single isolates from an MRSA case study AbstractAims. In phage therapy case studies, 1–3 bacteria isolates are typically tested against phages (phagogram). However, as bacteria populations differ

New phage therapy publication!🦠 #phagesky

We analysed an MRSA phage therapy case study, assessing how predictions made in vitro differed when using one (standard practice) or multiple bacteria isolates from the patient.

Collaborative work: Exeter and Queen Astrid hospital

doi.org/10.1093/jamb...

23.06.2025 14:19 β€” πŸ‘ 14    πŸ” 9    πŸ’¬ 2    πŸ“Œ 0
Emily presenting her talk

Emily presenting her talk

. @emgoodall.bsky.social presenting her cool new transposon-based method on discovery of novel small proteins #EESMicrobiology

24.06.2025 13:30 β€” πŸ‘ 12    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Happily representing @multidefence.bsky.social at the #EESMicrobiology in Heidelberg!
Come to my poster if interested in prophage-mediated phage defence!
Also don't miss @emgoodall.bsky.social's talk today, and @alekseiagapov.bsky.social and @davvi36.bsky.social posters!

24.06.2025 11:58 β€” πŸ‘ 30    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
Me showing off my poster

Me showing off my poster

Made it to Heidelberg for #EESMicrobiology @events.embl.org!
Find me at poster 240 and make to check out @annaolina.bsky.social & @alekseiagapov.bsky.social 's posters and @emgoodall.bsky.social 's talk to see everyone from the lab 😁

24.06.2025 11:24 β€” πŸ‘ 22    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0

🚨 Reminder! You have just over two weeks to submit an abstract, if you want to present at the @microbiologysociety.org meeting "Understanding and predicting microbial evolutionary dynamics" in Liverpool in November! #microsky πŸ¦ πŸ§«πŸ”¬

20.06.2025 14:35 β€” πŸ‘ 14    πŸ” 14    πŸ’¬ 0    πŸ“Œ 0

I'm sad to have missed this one, glad it went well! Hoping to make it again next year 🀞🏻

23.06.2025 10:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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How do multiple coexisting bacteria and phages (co)evolve? Well... they don't (or do so much less!

In this paper we tracked bacteria-phage (co)evolution in monoculture (individual bacteria-phage pairs) or in polyculture (all three pairs) over 6 weeks. Read more hereπŸ‘‡
doi.org/10.1099/mic....

20.06.2025 08:21 β€” πŸ‘ 18    πŸ” 10    πŸ’¬ 0    πŸ“Œ 3

I highly recommend this conference, i thoroughly enjoyed the 2022 meeting πŸ‘‡πŸ»

18.06.2025 17:56 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Poster of Understanding and predicting microbial evolutionary dynamics 2025 saying that abstracts are closing. With the date of the event and location.

Poster of Understanding and predicting microbial evolutionary dynamics 2025 saying that abstracts are closing. With the date of the event and location.

The abstract submission deadline for Understanding and predicting microbial evolutionary dynamics 2025 is soon approaching! Make sure to submit by 23:59 BST on 7 July 2025. microb.io/Abstracts #MicroEvo25

16.06.2025 15:00 β€” πŸ‘ 9    πŸ” 9    πŸ’¬ 1    πŸ“Œ 2

Well thats incredible!

30.05.2025 16:26 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Phage DisCo: targeted discovery of bacteriophages by co-culture | mSystems In this work, we describe a targeted phage discovery method that allows immediate isolation of phages with specific traits. Currently, to find a phage with specific properties, huge libraries of phage...

The latest work from my lab, Phage Disco, a method
@ellie-rand.bsky.social
developed for targeted discovery of bacteriophages based on the bacterial receptor, defense system, or other component they interact with, is now live in mSystems
journals.asm.org/doi/10.1128/...

29.05.2025 02:17 β€” πŸ‘ 103    πŸ” 39    πŸ’¬ 3    πŸ“Œ 1
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Plasmid–bacteria associations in the clinical context Antimicrobial resistance (AMR) is one of the most pressing global health problems, with plasmids playing a central role in its evolution and dissemination. Over the past decades, many studies have inv...

New opinion paper from the lab!

www.cell.com/trends/micro...

15.05.2025 09:09 β€” πŸ‘ 70    πŸ” 48    πŸ’¬ 3    πŸ“Œ 1

@davvi36 is following 18 prominent accounts