Sébastien Poulin

Initial Vancomycin Taper for the Prevention of Recurrent C difficile Infection This randomized clinical trial tested whether a 4-week pulse and taper vancomycin regimen was superior to a 2-week pulse regimen for preventing recurrence among patients with a first episode or first ...

The just published TAPER-V trial has lots of fun journal club things to discuss: jamanetwork.com/journals/jam...

Initial Vancomycin Taper for the Prevention of Recurrent C difficile Infection This randomized clinical trial tested whether a 4-week pulse and taper vancomycin regimen was superior to a 2-week pulse regimen for preventing recurrence among patients with a first episode or first ...

🔥Just published 🔥
TAPER-V RCT
In this RCT of 256, a 4-week vancomycin pulse and taper regimen *had a probability of 74% to be superior to a standard 2-week pulse regimen in patients a first episode or first recurrence of CDI
Vanco for 10d is obsolete! #IDSky #EMIMCC
jamanetwork.com/journals/jam...

🫠

bsky.app/profile/sebp...

Lenacapavir for PrEP was the big "star" of #CROI2026 after showing almost 100% effectiveness in preventing HIV in 2 large RCTs.
Unfortunately at a pricing point of 28000$ a year it remains inaccessible to most. A drug is only as great as the number of people who can access and benefit from it.

That’s a wrap from #CROI2026. Until next year in hopefully warm & sunny San Diego! But my writing has only just begun — look for reports on @pozmagazine.bsky.social & @aidsmap.bsky.social in coming days.

Meningococcal B (4CMenB) Vaccination for the Prevention of Gonorrhea in Men Who Have Sex With Men #CROI2026

credits @ hivvirology

🤨Comparative Effectiveness of 3 Benzathine Penicillin G-Based Regimens in PWH With Early Syphilis #CROI2026

credits @ hivvirology

Maybe…

But to be honest, I don’t like Sheifele

#suckermoveonEvansIn2021 😉

On second thoughts: Im glad Hutson and Caufield were not selected 🤪

Best place to follow #CROI2026 on social media👇
www.instagram.com/hivvirology/

100%

I hope USA team will be humble

(they won’t)

🔥Just published 🔥
ESCMID Clinical Guidelines on the Evaluation and Management of a Reported Antibiotic Allergy #IDSjy
www.clinicalmicrobiologyandinfection.org/article/S119...

#IDSky I always email residents rotating with me survival tips for their time of the ID consult service. I like to keep this short and high yield but I am constantly editing and improving the tip sheet. What would you add or remove. It cannot be longer that one page 😊.

snoop dogg is wearing glasses and a red turtleneck sweater and says i said what i said ALT: snoop dogg is wearing glasses and a red turtleneck sweater and says i said what i said

When I am declared God King Emperor, I am banning Cdiff PCR's

My top 10 ID papers for 2025. Full citations and descriptions available at clarityinitiative.org/hot-takes

Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com...

What were your top 10? Any thoughts about what I missed welcome!

#IDSky #Top10papers

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If the challenge (HBV vaccines in immunocompetent) didn't induce a humoral immunity (arbitrary >10), I wouldn't be super enthusiastic about its potential for good cellular immunity

We can argue about the arbitrary cutoff (10), but let's say we give 3 (or more) HBV shots and antiHBs are always 0 ? 🤷‍♂️

No CROI for me :/
Taking a break from meetings, we are understaffed +++ at 🏥
Mayyyybe IDSA Oct 2026 but not sure I wanna go back to Washington DC 😵‍💫

Beautiful, thank you 🙏

Grateful to have the opportunity to share this little piece of my heart. Love is always the answer.

academic.oup.com/cid/advance-...

a close up of a man 's face with a beard ALT: a close up of a man 's face with a beard

Me
(when my Georgia 🇺🇸 friend talks about winter)

~>5% of healthy adults do not develop anti-HBs >10) after completing a standard vaccine serie. I think it's fair for healthcare workers to know they were at least >10 once*

*then we can start arguing about the cutoff (10) and/or humoral vs cellular immunity, but I would prefer not to, if possible ?

very well done 👍

I highly recommend @patrickching.bsky.social latest commentary in @ashejournal.bsky.social describing:

-the history of contact precautions
-the need for balance ⚖️ between the benefits of gowns/gloves with their cost/environmental impact

www.cambridge.org/core/journal...

#IDSky

@antibioticdoc.bsky.social ✅

Why do so many celebrities say they have Lyme disease? | CBC News Chronic Lyme disease isn't recognized by conventional medicine. It's a controversial term used by some alternative practitioners to describe pain, fatigue and neurological symptoms they attribute to a...

Finally, a mainstream media article on a subject many of we infectious disease docs have to deal with on an almost daily basis.
It correctly identifies a “wellness” industry profit motive that drives the misinformation on this subject. www.cbc.ca/news/investi...

Browse the best of 2025! The Editors-in-Chief of cidjournal.bsky.social, jidjournal.bsky.social & ofidjournal.bsky.social have selected a collection of outstanding articles from 2025. Explore research on long COVID, AMR, HIV, influenza, vaccines & more: https://bit.ly/49Xgge6

paulsaxmd.bsky.social

When and How to Use Subcutaneous Antibiotics Subcutaneous administration of selected antibiotics provides a practical, safe alternative to intravenous therapy in patients with poor venous access, in o

Subcutaneous antibiotic administration is increasingly recognized as a valuable alternative to intravenous therapy in selected clinical contexts. In CID, authors summarize current clinical experience, PK/PD data, and technical aspects of subcutaneous infusion. https://bit.ly/3NB1jH5