Peter Seavill

Nanoemulsion modular assembly for the synthesis of functional mesoporous nanomaterials - Nature Synthesis Nanoemulsion modular assembly is emerging as a versatile strategy for synthesizing diverse functional mesoporous nanomaterials. This Review highlights the capabilities of nanoemulsion modular assembly...

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Review article by Dongyuan Zhao, Zuankai Wang & co-workers

Nanoemulsion modular assembly for the synthesis of functional mesoporous nanomaterials

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Photocatalytic coupling of unprotected sugars and N-heteroarenes - Nature Synthesis The synthesis of unprotected C-heteroaryl glycosides is challenging because of the lack of methods to utilize native saccharides as substrates. Now these compounds, capped as redox-active glycosyl sul...

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Article by Eric Chun Yong Chan, Ming Joo Koh & co-workers

Photocatalytic coupling of unprotected sugars and N-heteroarenes

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Enantio- and linear-selective allylic radical addition to imines using reductive cobalt catalysis - Nature Synthesis The linear-selective allylic addition to carbonyls remains challenging owing to the inversion of the six-membered transition state. Now an enantio- and linear-selective allylic addition to ketimines u...

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Article by Genping Huang, Yifeng Chen & co-workers

Enantio- and linear-selective allylic radical addition to imines using reductive cobalt catalysis

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Parallel paired electrolysis of industrial exhaust SO2 and diols for value-added sulfite esters synthesis - Nature Synthesis Paired electrolysis converts industrial SO2 directly into valuable cyclic sulfite esters, turning a common pollutant into useful chemicals. Mechanistic studies reveal key intermediates, offering a sus...

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Article by Zhenwei Wei, Wu Li, Hong Yi, Aiwen Lei & co-workers

Parallel paired electrolysis of industrial exhaust SO2 and diols for value-added sulfite esters synthesis

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Amino-acid-encoded assembly of programmable chiral Solomon links - Nature Synthesis An amino-acid-encoded assembly strategy is developed for the synthesis of programmable chiral Solomon links, featuring tunable cavity dimensions and shapes. This template-free synthetic approach favou...

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Article by Jinqiao Dong, Anthony P. Davis, Yong Cui & co-workers

Amino-acid-encoded assembly of programmable chiral Solomon links

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Article by Tao Xiong & co-workers

Catalytic asymmetric hydroalkylation of 1,1-dialkyl-substituted alkenes with unactivated alkyl electrophiles

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January issue is now online!

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Four covers from the issues of Nature Synthesis published in 2025.

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An Editorial highlighting some of the excellent covers featured in Nature Synthesis in 2025 as well as the research they represent. Thanks to our authors for submitting such great covers!

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Triphasic synthesis of MXenes with uniform and controlled halogen terminations - Nature Synthesis A gas–liquid–solid triphasic etching strategy is demonstrated to obtain MXenes with uniform and tunable halogen terminations. The resulting MXenes have highly ordered structures, enhanced charge trans...

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Article by Hai I. Wang, Minghao Yu, Xinliang Feng & co-workers

Triphasic synthesis of MXenes with uniform and controlled halogen terminations

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Customized cycloparaphenylene skeletons prepared via the intramolecular coupling of extended biphen[n]arenes - Nature Synthesis Intramolecular coupling of extended biphen[n]arenes is developed to yield cycloparaphenylenes (CPPs). The modular nature of biphen[n]arenes makes it possible to customize CPP structures, which permits...

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Article by Kang Cai, Dong-Sheng Guo, Jonathan L. Sessler, Chunju Li & co-workers

Customized cycloparaphenylene skeletons prepared via the intramolecular coupling of extended biphen[n]arenes

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Synthesis of wafer-scale uniaxially oriented tellurium films via molecular engineering - Nature Synthesis Using a molecular engineering approach, wafer-scale uniaxially oriented Te nanowire thin films are synthesized with excellent controllability and uniformity. The anchor-rope structural molecules form ...

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Article by Zhenxing Wang, Feng Wang, Qingdao Zeng, Zhenpeng Hu, Jun He & co-workers

Synthesis of wafer-scale uniaxially oriented tellurium films via molecular engineering

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Diastereodivergent construction of disubstituted cyclobutanes via electrochemical cobalt-catalysed reductive coupling - Nature Synthesis An electrochemical cobalt-catalysed reductive coupling reaction between alkynes and cyclobutenes enables diastereodivergent cyclobutane synthesis. By modulating the steric and electronic properties of...

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Article by Jie Yang, Hengxu Li, Qiong Wang & Qiang Liu

Diastereodivergent construction of disubstituted cyclobutanes via electrochemical cobalt-catalysed reductive coupling

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Catalytic asymmetric activation of bicyclobutanes - Nature Synthesis The precise manipulation of unfunctionalized hydrocarbons remains a fundamental challenge in chemical synthesis and catalysis. Here an organocatalytic asymmetric hydroxylation of bicyclobutanes with a...

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Article by Benjamin List & co-workers

Catalytic asymmetric activation of bicyclobutanes

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Direct oxygen-to-sulfur single-atom substitution of oxazoles and isoxazoles - Nature Synthesis A skeletal editing strategy for the direct conversion of oxazoles and isoxazoles into thiazoles and isothiazoles is described. These one-step transformations may be beneficial for drug development pro...

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Article by Li-Ping Xu, Hao Wei & co-workers

Direct oxygen-to-sulfur single-atom substitution of oxazoles and isoxazoles

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Sulfur enhances electrochemical CO2 reduction over porphyrin catalysts - Nature Synthesis The strategic placement of sulfur within a nickel porphyrin complex coupled with copper facilitates efficient electrochemical CO2 reduction to ethylene and ethanol.

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News & Views on the Article by Aoni Xu, Sung-Fu Hung & co-workers

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Sulfur enhances electrochemical CO2 reduction over porphyrin catalysts by Karl Adrian Gandionco, Zhiyuan Zhang & Jongwoo Lim

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meta-Selective radical halogenation of pyridines - Nature Synthesis Radical processes can be leveraged to impart meta selectivity in pyridine functionalization, offering a valuable approach for the late-stage functionalization of bioactive molecules.

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News & Views on the Articles:

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meta-Selective radical halogenation of pyridines by Nirmala Mohanta & Jacquelyne A. Read

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Ammonia synthesis over AuRu alloys - Nature Synthesis Nature Synthesis - Ammonia synthesis over AuRu alloys

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Ammonia synthesis over AuRu alloys by @alexrgroves.bsky.social

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Highlighting the @natenergy.nature.com Article by Lin Yuan, Junwei Lucas Bao, Jennifer A. Dionne & co-workers
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A terminal germanium oxido dianion - Nature Synthesis Nature Synthesis - A terminal germanium oxido dianion

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A terminal germanium oxido dianion by Bei Zhang

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Highlighting the @jacs.acspublications.org article by Valentin D. Hannibal & Lutz Greb
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Synthesis of discrete oligoethylenes towards chemically recyclable polyolefins - Nature Synthesis The precision synthesis of uniform oligoethylenes with chain lengths of up to 576 carbon atoms is achieved via an iterative growth approach based on the Julia–Kocienski reaction. The oligoethylenes ar...

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Article by Rui Tan, Shiyong Liu, Zhengbiao Zhang & co-workers

Synthesis of discrete oligoethylenes towards chemically recyclable polyolefins

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Artificial synthesis of carbohydrates from electrochemically fixed carbon dioxide - Nature Synthesis The sustainable synthesis of carbohydrates from CO2 is challenging due to the complexity of controlled CO2 reduction. Here a two-step method for the sustainable synthesis of C5+ carbohydrates is repor...

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Article by Peidong Yang, Hailiang Wang & co-workers

Artificial synthesis of carbohydrates from electrochemically fixed carbon dioxide

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Alkyl sulfonyl fluorides as ambiphiles in the stereoselective palladium(II)-catalysed cyclopropanation of unactivated alkenes - Nature Synthesis The ambiphilic reactivity of alkyl sulfonyl fluorides in stereoselective cyclopropanation under Pd(II) catalysis is reported. The method provides convenient access to cis-disubstituted cyclopropanes t...

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Article by Pavel K. Mykhailiuk, Peng Liu, K. Barry Sharpless, Keary M. Engle & co-workers

Alkyl sulfonyl fluorides as ambiphiles in the stereoselective palladium(II)-catalysed cyclopropanation of unactivated alkenes

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Article by Roly J. Armstrong, Erli Lu, Koji Kubota, Hajime Ito & co-workers

Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides

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Scalable ultrathin sodium metal anodes - Nature Synthesis Sodium metal is of interest for high-energy-density batteries, but the lack of large-area ultrathin sodium metal foils hinders research. Here a metre-length, ultrathin (≤50 μm), mechanically strengthe...

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Article by Jianwei Nai, Lin Guo, Hua Wang & co-workers

Scalable ultrathin sodium metal anodes

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Heck-type reactions with bismuth photocatalysts - Nature Synthesis Nature Synthesis - Heck-type reactions with bismuth photocatalysts

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Heck-type reactions with bismuth photocatalysts by Eric Piechota

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Highlighting the Nature Catalysis Article by Josep Cornella & co-workers

December issue is now online!

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Biosynthesis of plant vitexin-derived flavonoid glycosides in yeast - Nature Synthesis Microbial biosynthesis is a promising alternative to plant extraction to obtain post-modified flavonoids, but current de novo biosynthesis is limited to milligrams per litre. Now the production of pla...

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Article by Min Ye, Xue Qiao, Menghao Cai & co-workers

Biosynthesis of plant vitexin-derived flavonoid glycosides in yeast

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Laser-assisted materials engineering at the atomic and nanoscales - Nature Synthesis Laser technology offers high energy, precise spatial resolution and seamless automation for materials synthesis and device fabrication. This Review highlights laser-assisted materials engineering at t...

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Review article by Weihua Guo, Zihao Li, Libei Huang, Ma Qian, James M. Tour & Ruquan Ye

Laser-assisted materials engineering at the atomic and nanoscales

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Molecular organohalides as general precursors for direct synthesis of two-dimensional transition metal carbide MXenes - Nature Synthesis Ti-, Zr- and Nb-based MXenes with Cl, Br or mixed terminations can be synthesized by a bottom-up, atom-economic route directly from metals and molecular organohalides. The reactivity of organohalide p...

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Article by Dmitri V. Talapin & co-workers

Molecular organohalides as general precursors for direct synthesis of two-dimensional transition metal carbide MXenes

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Heuristic data-driven approach for synergistic cobalt(IV)–enamine catalysis - Nature Synthesis Discovering new chemical reactions is often a slow process. Now a data-driven strategy that integrates expert intuition with artificial intelligence-guided exploration enables the rapid identification...

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Article by Qi Yang, Sanzhong Luo & co-workers

Heuristic data-driven approach for synergistic cobalt(IV)–enamine catalysis

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News & Views on the Article by Yan Liu, Yong Cui & co-workers

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Helically ordered polymers under metal–organic framework confinement by Natalia M. Padial & Carlos Martí-Gastaldo

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