Gianmaria Liccardi's Avatar

Gianmaria Liccardi

@gianmaria-liccardi.bsky.social

Group leader, Liccardi lab, Institute of biochemistry, University of Cologne. We are interested in cell death inflammation and immunity.

597 Followers  |  697 Following  |  13 Posts  |  Joined: 18.11.2024  |  1.7935

Latest posts by gianmaria-liccardi.bsky.social on Bluesky

Fantastic work in collaboration with @vonkarstedtlab.bsky.social available on Cell Death & Discovery. Ibrutinib sensitises to ferroptosis induction to kill DLBCL. #cancer #lymphoma #dlbcl

doi.org/10.1038/s414...

01.11.2025 20:06 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you @fattoquotidiano.bsky.social for covering our @nature.com article.

www.ilfattoquotidiano.it/2025/08/21/m...

Reserach article: doi.org/10.1038/s415...

05.10.2025 06:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

The STING of death continues!
Thanks to @natrevrheum.nature.com (doi.org/10.1038/s415... & rdcu.be/eJjhl ) for highlighting our recent @nature.com paper (doi.org/10.1038/s415...) cell death inhibition as a therapy for autoinflammatory diseases (SAVI)
#immunity #celldeath #rheumatology #vasculitis

03.10.2025 13:01 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Just found this post from
Nature on the AAP of our paper. Soon the official print version…

29.09.2025 20:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you πŸ™

21.08.2025 06:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you πŸ™

21.08.2025 06:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you πŸ™

21.08.2025 06:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This work was funded by BCCologne, SFB1530, SFB1399 and the CANTAR network and supported by the SFB_1403

21.08.2025 06:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

A special thanks to Henning Walczak for all his support.
Thanks also to all other collaborators: Trifunovic lab, Federica Locci, Martin Peifer , Fabrizio De Bendetti, Giusi Prencipe and Antonella Insalaco.

21.08.2025 06:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Our work shows that STING triggers ZBP1-mediated necroptosis independently of TNFR1 and FADD. Inhibiting necroptosis prevents STING-associated vasculopathy with onset in infancy (SAVI), paving the way for cell death inhibition as a therapeutic strategy for STING-driven inflammatory diseases

21.08.2025 06:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD - Nature Nature - STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD

I am beyond excited and incredibly proud to share that our work is now out in @nature.com This discovery was made possible thanks to the first author Kostas kelepouras, my fantastic lab , and the unique research environment here in Cologne in collaboration with the Hospital bambino Gesu in Rome.

21.08.2025 06:12 β€” πŸ‘ 212    πŸ” 105    πŸ’¬ 2    πŸ“Œ 0
Post image

In my lab we are interested in understanding how aberrant activation of cell death & inflammation drive loss of tissue homeostasis and how genetic instability contributes to the loss of this balance. If you are interested in discussing this topic, joining our lab or collaborate please let me know.

23.11.2024 11:45 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Just back from the TNF CONFERENCE in China, Full of ideas and inspiration. Thank you to the organisers for such an amazing conference and line up of fantastic speakers #tnf #celldeath #innateimmunity

18.11.2024 11:17 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

@gianmaria-liccardi is following 20 prominent accounts