The role of perturbation of our circadian clock plays in promoting the fibrosis (scarring) of organs
www.jci.org/articles/vie...
@reddysunila.bsky.social
Clinical Pharmacologist; Aspiring Gardner; Cooking Enthusiast; #IDSky #HIV #COVID19 #PharmSky #EmergingViruses
The role of perturbation of our circadian clock plays in promoting the fibrosis (scarring) of organs
www.jci.org/articles/vie...
Children and teens who had a Covid reinfection had a doubling of #LongCovid risk (PASC) and a significant increase in many other adverse outcomes (Figure) www.thelancet.com/journals/lan...
30.09.2025 22:35 β π 490 π 290 π¬ 15 π 17Tracking #SARSCoV2 #Lineages - Globally |09/01/25
Top lineages -#30DayTrends #G30 
XFG  (31.5%)
XFG.3  (20%)
NB.1.8.1  (13.4%)
XFG.2  (6%)
PQ.2  (5%)
XFG.3.1  (3.5%)
PQ.1  (1.8%)
LP.8.1.1  (1.3%)
PQ.10  (1.3%)
MC.10.2.1  (1.2%)
Tracker:  public.tableau.com/app/profile/... 1/n
Sept 5th update:
Wastewater data is trending reasonably closely to the Aug 1st model, which predicts a peak this week.  High levels in the south/wetst, but it's the smallest wave since 2020.
πΈ480,000 new infections/day
πΈ1 in 70 currently infected
πΈ1 in 180 infectious out of household
The new FDA recommendations on the Covid booster are confusing at best.
We clarify what they mean and how it directly impacts access nationwide. 
@nbcnews.com
We just learned about a 3rd dimension of how Covid can affect our arteries.
erictopol.substack.com/p/covid-and-...
Tracking #SARSCoV2 #Lineages - Globally |08/09/25
Top lineages -#30DayTrends #G30
XFG  (24%)
XFG.3  (16.3%)
NB.1.8.1  (15.7%)
XFG.2  (6.2%)
PQ.2  (4.5%)
XFG.3.1  (4.3%)
LP.8.1.1  (3.6%)
PQ.1  (2.1%)
PY.1  (1.3%)
PQ.4  (1.2%)
PF.2  (1%)
Tracker:  public.tableau.com/app/profile/...
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Aug 1st Update + Forecast π
Wastewater jumped this week, and is now increasing in most locations. Current model forecast suggests a peak in early Sept at around 500-600k.  This would imply a step down from last summer.
πΈοΈ290k daily infections
πΈοΈ1:280 currently infectious
Enjoying the last of summer blooms #gardening π±
12.08.2025 23:58 β π 5 π 0 π¬ 0 π 0#hibiscus #gardening π±
09.08.2025 16:27 β π 3 π 0 π¬ 0 π 0Vibrant okra flowers #gardening π±
25.07.2025 18:52 β π 1 π 0 π¬ 0 π 0Dahlias are having their moment #gardening π±
15.07.2025 15:55 β π 2 π 0 π¬ 0 π 0Estrogen use,  in women at menopause, is linked to a youthful immune system clock 
erictopol.substack.com/p/new-anti-a...
Mini perks of gardeningβ¦watching a bumblebee drink nectar #gardening π±
06.07.2025 19:03 β π 0 π 0 π¬ 0 π 0Planting Happiness! #gardening π±
14.06.2025 15:44 β π 2 π 0 π¬ 0 π 0Blooming Phlox π± #gardening
11.06.2025 11:33 β π 3 π 0 π¬ 0 π 0President Trump has long amplified debunked or baseless theories. On Saturday, he shared a conspiracy theory on social media that falsely claimed former President Biden had been executed and replaced by a robot. It was the latest outlandish claim he has promoted online to millions of followers.
02.06.2025 00:45 β π 878 π 262 π¬ 270 π 80It was an honor to give commencement at the @harvard @harvardchansph School of Public Health this year.
The new graduates give me hope.
What is the meaning of VERITAS? TRUTH
Video courtesy of Harvard T.H. Chan School of Public Health.
www.youtube.com/live/RtyLHjo...
www.youtube.com/watch?v=RtyL...
Brilliant speech by Dr Gounder (starting at 1:12) regarding challenges facing Public Health. Have a listenβ¦.
Tracking #SARSCoV2 #Lineages - Globally |05/24/25
Top lineages -#30DayTrends #G30
LP.8.1.1  (17.1%)
NB.1.8.1   (12.6%)π
PC.2  (6.2%)
XFG  (3.9%)π
XEC.25.1  (3%)
LP.8.1  (2.8%)
XEC  (2.6%)
LP.8.1.6 (2.3%)
XFJ  (2.3%)
XEC.4  (2.1%)
Tracker:  public.tableau.com/app/profile/...
1/n
May 23rd update + πForecast:
Wastewater and ED were flat this week. XFG growth is expected to start the summer wave within ~a month. XFG will likely be dominant in New York within ~10 days
Estimates:
πΈ175,000 new infections/day
πΈ~1 in 190 currently infected
πΈ~1 in 475 are reasonably infectious
Late Friday, the FDA granted the company full approval for its vaccine for use only in adults 65 and older β or those 12 to 64 who have at least one health problem that puts them at increased risk from COVID-19. 
buff.ly/nn3gtZ4
Blooming peonies #gardening π±
15.05.2025 19:22 β π 4 π 0 π¬ 0 π 0May 9th update:
No sign yet of the summer wave.  All states decreasing or flat except for (maybe?) Hawaii with a slight increase. Watching XFG and NB.1.8.1 growth for the summer wave. 
 Estimates:
πΈ190,000 new infections/day
πΈ~1 in 173 currently infected
After the rain #gardening π±
14.05.2025 18:57 β π 3 π 0 π¬ 0 π 0Peonies are about to burstβ¦#gardening π±
14.05.2025 12:50 β π 1 π 0 π¬ 0 π 0Happy Motherβs Day! #gardening π±
09.05.2025 23:33 β π 0 π 0 π¬ 0 π 0Larger than life tulips #gardening π±
30.04.2025 23:58 β π 3 π 0 π¬ 0 π 0#COVID19 #VariantDashboard - #USA| 04/29/25
#SARSCoV2 #Lineages #30DAYTRENDS
LP.8.1.1  (39.3%)
LP.8.1  (18.4%)
LF.7  (13.3%)
XEC  (4.1%)
LF.7.2.1  (2.2%)
MC.10.1  (2.2%)
NB.1.8.1  (2%)
LP.8.1.2  (1.8%)
--
XFJ   (1%)
Tracker: tinyurl.com/mryj4uu7
1/n